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  1. Content type: Research

    Patient reported outcome measures (PROMs) and minimal clinically important differences (MCIDs) are included in Canada’s Common Drug Review (CDR) process to approve new drugs. Often, the measures report on the ...

    Authors: Allison Soprovich, Meghan Ingstrup and Dean T. Eurich

    Citation: Health and Quality of Life Outcomes 2019 17:4

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  2. Content type: Research

    Health-related quality of life (HRQoL) is a multidimensional concept with significant effects and children and adolescence; while physical activity (PA) and screen time (ST) have been suggested as its probable...

    Authors: Nazgol Motamed-Gorji, Mostafa Qorbani, Fatemeh Nikkho, Mojgan Asadi, Mohammad Esmaeil Motlagh, Omid Safari, Tahereh Arefirad, Hamid Asayesh, Rasool Mohammadi, Morteza Mansourian and Roya Kelishadi

    Citation: Health and Quality of Life Outcomes 2019 17:2

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  3. Content type: Research

    Research on quality of life QOL is limited in Brazil and few studies have examined the association between smoking status and quality of life. This study addresses this gap and also examines the association be...

    Authors: Dayane Aparecida Viana, Flavia Cristina Drumond Andrade, Luiz Claudio Martins, Leiner Resende Rodrigues and Darlene Mara dos Santos Tavares

    Citation: Health and Quality of Life Outcomes 2019 17:1

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  4. Content type: Review

    This study aims to provide a systematic compilation of existing measures of self-efficacy developed specifically for use in cancer patients and provide descriptions and comparative evaluations of the character...

    Authors: Fei-Fei Huang, Qing Yang, An-ni Wang and Jing-Ping Zhang

    Citation: Health and Quality of Life Outcomes 2018 16:241

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  5. Content type: Short report

    The isotemporal substitution (IS) approach can be used to assess the effect of replacing one activity with the equal duration of another activity on relevant outcomes. This study examined the associations of o...

    Authors: Akitomo Yasunaga, Ai Shibata, Kaori Ishii, Shigeru Inoue, Takemi Sugiyama, Neville Owen and Koichiro Oka

    Citation: Health and Quality of Life Outcomes 2018 16:240

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  6. Content type: Research

    Psychosocial models including illness perception might explain individual differences in health-related quality of life (HRQoL) and daily functioning in chronically ill patients. The aim of this study was to a...

    Authors: Carolin Berner, Ludwig Erlacher, Karl Heinrich Fenzl and Thomas E. Dorner

    Citation: Health and Quality of Life Outcomes 2018 16:238

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  7. Content type: Review

    Duchenne Muscular Dystrophy (DMD) is a severe, life-limiting and incurable condition. However, studies estimating quality of life and those measuring actual quality of life in people living with DMD vary consi...

    Authors: Lesley Uttley, Jill Carlton, Helen Buckley Woods and John Brazier

    Citation: Health and Quality of Life Outcomes 2018 16:237

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  8. Content type: Research

    Quality Adjusted Life Years (QALYs) are a key outcome measure widely used within health technology assessment and health service research studies. QALYs combine quantity and quality of life, with quality of li...

    Authors: Mónica Duarte Oliveira, Andreia Agostinho, Lara Ferreira, Paulo Nicola and Carlos Bana e Costa

    Citation: Health and Quality of Life Outcomes 2018 16:235

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  9. Content type: Research

    FertiQoL is a questionnaire internationally developed to measure fertility-specific quality of life. It has been validated with infertile populations in many countries and used in several studies focusing on t...

    Authors: R. E. Sexty, G. Griesinger, J. Kayser, M. Lallinger, S. Rösner, T. Strowitzki, B. Toth and T. Wischmann

    Citation: Health and Quality of Life Outcomes 2018 16:233

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  10. Content type: Research

    The Early Childhood Oral Health Impact Scale (ECOHIS) measures the impact of dental diseases on Oral Health-Related Quality of Life both in children and their families. The aim of this study was to develop a C...

    Authors: Carlos Zaror, Claudia Atala-Acevedo, Gerardo Espinoza-Espinoza, Patricia Muñoz-Millán, Sergio Muñoz, María José Martínez-Zapata and Montse Ferrer

    Citation: Health and Quality of Life Outcomes 2018 16:232

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  11. Content type: Research

    Leakage is a major concern for people who use a stoma, but people’s experience and its impact is not well understood. This study aimed to establish a definition of leakage through clinical and user input. This...

    Authors: Beenish Nafees, Zenia M. Størling, Charlotte Hindsberger and Andrew Lloyd

    Citation: Health and Quality of Life Outcomes 2018 16:231

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  12. Content type: Research

    Cancer and its treatment can result in psychological distress in both adults with cancer and in their family caregivers. This psychological distress acts as a significant adverse factor in patient-caregiver dy...

    Authors: Qiuping LI, Yi LIN, Yinghua XU and Huiya ZHOU

    Citation: Health and Quality of Life Outcomes 2018 16:230

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  13. Content type: Research

    This study examined the psychometric properties of version 2 of the SF-12 Health Survey (SF-12v2) among adults with hemophilia in the United States.

    Authors: Ruchitbhai M. Shah, Benjamin F. Banahan III, Erin R. Holmes, Amit S. Patel, Marie Barnard, Rahul Khanna and John P. Bentley

    Citation: Health and Quality of Life Outcomes 2018 16:229

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  14. Content type: Review

    Interpretation of differences or changes in patient-reported outcome scores should not only consider statistical significance, but also clinical relevance. Accordingly, accurate determination of the minimally ...

    Authors: Ahmad Ousmen, Célia Touraine, Nina Deliu, Francesco Cottone, Franck Bonnetain, Fabio Efficace, Anne Brédart, Caroline Mollevi and Amélie Anota

    Citation: Health and Quality of Life Outcomes 2018 16:228

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  15. Content type: Research

    Pressure ulcer-specific patient-reported outcome (PRO) instruments should be used to inform patient care and provide a strong evidence base for interventions aimed at preventing pressure ulcers. The aim was to...

    Authors: Claudia Rutherford, Julia M. Brown, Isabelle Smith, Elizabeth McGinnis, Lyn Wilson, Rachael Gilberts, Sarah Brown, Susanne Coleman, Howard Collier and Jane Nixon

    Citation: Health and Quality of Life Outcomes 2018 16:227

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  16. Content type: Short report

    Responsiveness and minimal important change (MIC) are central measurement properties when interpreting scores from health questionnaires. The aim of the study was to evaluate the responsiveness and MIC of the ...

    Authors: Cecilie Rud Budtz, Johan Hviid Andersen, Nils-Bo de Vos Andersen and David Høyrup Christiansen

    Citation: Health and Quality of Life Outcomes 2018 16:226

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  17. Content type: Research

    This study evaluates the descriptive and psychometric properties of the Persian version of the Weiss Functional Impairment Rating Scale-Parent Report Form (WFIRS-P) in a normal sample of Iranian children.

    Authors: Behnaz Kiani, Habib Hadianfard and Margaret D. Weiss

    Citation: Health and Quality of Life Outcomes 2018 16:225

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  18. Content type: Commentary

    With the growth of patient-reported outcome (PRO) measurement, questions arise regarding how copyright protection applies to PRO instruments in general and to their translations in particular. The main objecti...

    Authors: Caroline Anfray, Benjamin Arnold, Mona Martin, Sonya Eremenco, Donald L. Patrick, Katrin Conway and Catherine Acquadro

    Citation: Health and Quality of Life Outcomes 2018 16:224

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  19. Content type: Research

    To ascertain whether person centred coordinated care (P3C) is being delivered in healthcare services, components relating to the construct need to be measured. Patient reported measures (PRMs) can be used to p...

    Authors: Hannah Wheat, Jane Horrell, Jose M. Valderas, James Close, Ben Fosh and Helen Lloyd

    Citation: Health and Quality of Life Outcomes 2018 16:223

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  20. Content type: Research

    Development of innovative drugs for melanoma is occurring rapidly. Incremental gains in overall survival amongst innovative products may be difficult to measure in clinical trials, and their use may be associa...

    Authors: Amr Makady, Rachel R. J. Kalf, Bettina Ryll, Gilliosa Spurrier, Anthonius de Boer, Hans Hillege, Olaf H. Klungel and Wim Goettsch

    Citation: Health and Quality of Life Outcomes 2018 16:222

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  21. Content type: Research

    Health-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients’ perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate the ...

    Authors: Yen Shing Yeoh, Gerald Choon-Huat Koh, Chuen Seng Tan, Kim En Lee, Tian Ming Tu, Rajinder Singh, Hui Meng Chang, Deidre A. De Silva, Yee Sien Ng, Yan Hoon Ang, Philip Yap, Effie Chew, Reshma Aziz Merchant, Tseng Tsai Yeo, Ning Chou, N. Venketasubramanian…

    Citation: Health and Quality of Life Outcomes 2018 16:221

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  22. Content type: Research

    Absence of context-specific clinically validated cut-off values for assessing burnout as a dichotomous phenomenon has hindered the progress of student burnout research with regard to quantifying the magnitude ...

    Authors: Nuwan Darshana Wickramasinghe, Devani Sakunthala Dissanayake and Gihan Sajiwa Abeywardena

    Citation: Health and Quality of Life Outcomes 2018 16:220

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  23. Content type: Review

    To examine the existing body of knowledge on quality of life (QoL) in partners of people with substance use problems (PP-SUPs) to provide a synthesized summary of the evidence and identify gaps in our knowledg...

    Authors: Bente Birkeland, Kim Foster, Anne S. Selbekk, Magnhild M. Høie, Torleif Ruud and Bente Weimand

    Citation: Health and Quality of Life Outcomes 2018 16:219

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  24. Content type: Research

    The aim of this study was to translate and validate an Arabic version of the 5-item Oral Health Impact Profile (OHIP).

    Authors: Mohammed Nasser Alhajj, Esam Halboub, Nadia Khalifa, Abdullah G. Amran, Daniel R. Reissmann, Abbas G. Abdullah, Mounzer Assad, Abdulghani A. Al-Basmi and Fawaz A. Al-Ghabri

    Citation: Health and Quality of Life Outcomes 2018 16:218

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  25. Content type: Correction

    The original article [1] contains a number of statements that the authors would like to be disregarded, noted ahead

    Authors: Huang-Tz Ou, Pei-Chi Chen, Meng-Hsing Wu and Chung-Ying Lin

    Citation: Health and Quality of Life Outcomes 2018 16:217

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    The original article was published in Health and Quality of Life Outcomes 2016 14:119

  26. Content type: Research

    Adherence to long-term chelation therapy in transfusion-dependent patients is critical to prevent iron overload-related complications. Once-daily deferasirox dispersible tablets (DT) have proven long-term effi...

    Authors: Ali T. Taher, Raffaella Origa, Silverio Perrotta, Alexandra Kouraklis, Giovan Battista Ruffo, Antonis Kattamis, Ai-Sim Goh, Vicky Huang, Aiesha Zia, Raquel Merino Herranz and John B. Porter

    Citation: Health and Quality of Life Outcomes 2018 16:216

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  27. Content type: Research

    Little is known about how patient reported barriers to health care impact the quality of life (HRQoL) of patients with comorbid disease. We investigated patient reported barriers to health care and low physica...

    Authors: Edward Zimbudzi, Clement Lo, Sanjeeva Ranasinha, Gregory Fulcher, Martin Gallagher, Stephen Jan, Peter G. Kerr, Helena J. Teede, Kevan R. Polkinghorne, Grant Russell, Rowan G. Walker and Sophia Zoungas

    Citation: Health and Quality of Life Outcomes 2018 16:215

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  28. Content type: Research

    Health-related quality of life (QoL) is a comprehensive, multidimensional construct encompassing physical and psychosocial wellbeing. Physicians frequently assess QoL as part of their decision making process w...

    Authors: Orly Tamir, Nitzan Shabo De-Paz, David Dvir and Anthony D. Heymann

    Citation: Health and Quality of Life Outcomes 2018 16:214

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  29. Content type: Research

    Facial palsy is known to have correlations with low level of quality of life. However, little is known about the association between preference based health-related quality of life (HRQoL) and paralytic side o...

    Authors: Sina Kim, Hye-Yoon Lee, Nam-Kwen Kim, Tae Han Yook, Eun-Sung Seo and Jong Uk Kim

    Citation: Health and Quality of Life Outcomes 2018 16:213

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  30. Content type: Research

    Obstetric brachial plexus injuries (OBPIs) are rare but can have significant implications for those affected, their caregivers and the health system. Symptoms can range from restricted movement to complete par...

    Authors: Christopher W. H. Yau, Elena Pizzo, Chetankumar Prajapati, Tim Draycott and Erik Lenguerrand

    Citation: Health and Quality of Life Outcomes 2018 16:212

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  31. Content type: Research

    In order to better understand the perspectives of patients and physicians regarding the treatment and management of rheumatoid arthritis (RA), we present and compare results from a patient-based and a physicia...

    Authors: Allan Gibofsky, James Galloway, Joern Kekow, Cristiano Zerbini, Maria de la Vega, Gavin Lee, Eun Young Lee, Catalin Codreanu, Cheryl Koehn, Kathy Steinberg, Eustratios Bananis, Dario Ponce de Leon, Anna Maniccia and Ara Dikranian

    Citation: Health and Quality of Life Outcomes 2018 16:211

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  32. Content type: Research

    To generate Chinese population norms for the EQ-5D-5L dimensions, EQ-VAS (Visual Analogue Scale) scores and EQ-5D-5L index scores, stratified by gender and age. The EQ-5D is a widely used generic health-relate...

    Authors: Zhihao Yang, Jan Busschbach, Gordon Liu and Nan Luo

    Citation: Health and Quality of Life Outcomes 2018 16:210

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  33. Content type: Research

    The rare disease, Hunter Syndrome (mucopolysaccharidosis type II; MPS II), characterized by iduronate-2-sulfatase deficiency, has heterogeneous symptoms often including cognitive impairment (CI). To evaluate p...

    Authors: Maria Mattera, Margaret K. Vernon, Mireia Raluy-Callado and Jaromir Mikl

    Citation: Health and Quality of Life Outcomes 2018 16:209

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  34. Content type: Research

    When measuring the treatment effect in tinnitus with multi-item outcome instruments, it is crucial for both clinical and research purposes to take into consideration clinical importance of the outcome scores. ...

    Authors: Henryk Skarżyński, Elżbieta Gos, Beata Dziendziel, Danuta Raj-Koziak, Elżbieta A. Włodarczyk and Piotr H. Skarżyński

    Citation: Health and Quality of Life Outcomes 2018 16:208

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  35. Content type: Research

    Chronic non-specific neck pain is related to limited cervical mobility, impaired function, neck muscles myofascial pain syndrome, and stress at work. The aforementioned factors are strongly related and may lea...

    Authors: Ester Cerezo-Téllez, María Torres-Lacomba, Orlando Mayoral-del-Moral, Soraya Pacheco-da-Costa, David Prieto-Merino and Beatriz Sánchez-Sánchez

    Citation: Health and Quality of Life Outcomes 2018 16:207

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  36. Content type: Research

    Currently there is no diabetes-specific quality of life (QOL) instrument available in Lithuanian language. We aimed to develop a Lithuanian version of a widely-used individualised instrument - the Audit of Dia...

    Authors: Žydrūnė Visockienė, Laura Narkauskaitė-Nedzinskienė, Roma Puronaitė and Aldona Mikaliūkštienė

    Citation: Health and Quality of Life Outcomes 2018 16:206

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  37. Content type: Research

    The COPD Assessment Test (CAT) contains eight items (cough, phlegm, chest tightness, breathlessness, limited activities, confidence leaving home, sleeplessness and energy). The current study aimed 1) to better...

    Authors: Sarah Houben-Wilke, Daisy J. A. Janssen, Frits M. E. Franssen, Lowie E. G. W. Vanfleteren, Emiel F. M. Wouters and Martijn A. Spruit

    Citation: Health and Quality of Life Outcomes 2018 16:205

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  38. Content type: Research

    The EQ-5D-3 L instrument is a standardized questionnaire which was developed as a simple, generic measure of health for clinical and economic appraisal. To aid in the interpretation, scores are often compared ...

    Authors: Knut Stavem, Liv A Augestad, Ivar S Kristiansen and Kim Rand

    Citation: Health and Quality of Life Outcomes 2018 16:204

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  39. Content type: Research

    Families play a critical role in supporting the health and well-being of children with chronic illnesses, who face a lifetime of responsibility for self-management of their condition. Our goal was to investiga...

    Authors: Kathryn E. Flynn, Harald Kliems, Nikita Saoji, Jacob Svenson and Elizabeth D. Cox

    Citation: Health and Quality of Life Outcomes 2018 16:203

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  40. Content type: Research

    Defining the minimally clinically important difference (MCID) is important for the design and analysis of clinical trials and ensures that findings are clinically meaningful. Studies in adult populations have ...

    Authors: Amberly Brigden, Roxanne M Parslow, Daisy Gaunt, Simon M Collin, Andy Jones and Esther Crawley

    Citation: Health and Quality of Life Outcomes 2018 16:202

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  41. Content type: Review

    Low health literacy often has an association with poor health outcomes such as low levels of self-efficacy, increased mortality, poor health status and reduced quality of life (QOL). The aim of the study was t...

    Authors: Mengyun Zheng, Hui Jin, Naiyang Shi, Chunxiao Duan, Donglei Wang, Xiaoge Yu and Xiaoning Li

    Citation: Health and Quality of Life Outcomes 2018 16:201

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  42. Content type: Research

    The Hip disability and Osteoarthritis Outcome Score (HOOS) is a self-administered hip-specific questionnaire intended to evaluate symptoms and functional limitations, and it is commonly used to evaluate interv...

    Authors: A Sundén, K Lidengren, E M Roos, L S Lohmander and E Ekvall Hansson

    Citation: Health and Quality of Life Outcomes 2018 16:200

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  43. Content type: Research

    Measurement of quality of life demands thoroughly developed and validated instruments. The development steps from theory to concepts and from empirical data to items are sparsely described in the literature of...

    Authors: Louise Norman Jespersen, Susan Ishøy Michelsen, Bjørn Evald Holstein, Tine Tjørnhøj-Thomsen and Pernille Due

    Citation: Health and Quality of Life Outcomes 2018 16:199

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  44. Content type: Research

    Central venous catheters (CVC) have been widely used for patients with severe conditions. However, they increase the risk of catheter-related bloodstream infection (CRBSI), which is associated with high econom...

    Authors: Yuanyi Cai, Min Zhu, Wei Sun, Xiaohong Cao and Huazhang Wu

    Citation: Health and Quality of Life Outcomes 2018 16:198

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  45. Content type: Research

    Health-related quality of life (QoL) deteriorates immediately after esophagectomy. Patients may benefit from periodic assessments to detect increased morbidity on the basis of subjective self-reports. Using in...

    Authors: Minji K. Lee, Kathleen J. Yost, Karlyn E. Pierson and Shanda H. Blackmon

    Citation: Health and Quality of Life Outcomes 2018 16:197

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  46. Content type: Research

    The concept of hope has been measured using the Herth Hope Index (HHI) in different samples, but varying factor structures comprising different items from the HHI have been reported. Therefore, further testing...

    Authors: Tone Rustøen, Anners Lerdal, Caryl Gay and Anders Kottorp

    Citation: Health and Quality of Life Outcomes 2018 16:196

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