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Featured article: overcoming knowledge gaps on the burden of disease caused by meningococcal disease

New Content Item​​​​​​​Invasive meningococcal disease (IMB) occurs most commonly in children. There can be challenges in estimating the long term quality of life of IMD survivors.

In this study, researchers conducted a DELPHI questionnaire to identify knowledge gaps and to seek consensus on appropriate methods and study designs when investigating the burden caused by IMD.

To read the full research article, click here.

Articles

  1. Content type: Research

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    Authors: Matthew F. Jacques, Rachel C. Stockley, Gladys L. Onambele-Pearson, Neil D. Reeves, Georgina K. Stebbings, Ellen A. Dawson, Lynne Groves and Christopher I. Morse

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Aims and scope

Health and Quality of Life Outcomes considers original manuscripts on the Health-Related Quality of Life (HRQOL) assessment for evaluation of medical and psychosocial interventions. It also considers approaches and studies on psychometric properties of HRQOL and patient reported outcome measures, including cultural validation of instruments if they provide information about the impact of interventions. The journal publishes study protocols and reviews summarising the present state of knowledge concerning a particular aspect of HRQOL and patient reported outcome measures. Reviews should generally follow systematic review methodology. Comments on articles and letters to the editor are welcome.

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Editor profile

Prof Holger J. Schünemann, Editor-in-Chief

As internist and clinical epidemiologist, Prof Schünemann, M.D., Ph.D., M.Sc., FRCP(C), holds the position of chair of the department of Clinical Epidemiology and Biostatistics at McMaster University, Hamilton, Canada, considered the birthplace of evidence-based medicine and problem based learning. He graduated from the Medical School of Hannover, Germany, in 1993, and trained in epidemiology (Ph.D. in 2000), preventive medicine/public health and internal medicine at the Medical School of Hannover, Germany, and at the State University of New York (SUNY) at Buffalo, USA.

He authored over 300 peer reviewed publications, books and book chapters, many of them focusing on patient reported outcomes, clinical practice guideline methodology and systematic reviews. Among other instruments, he co-developed the self-administered standardized Chronic Respiratory Questionnaire (CRQ-SAS), a disease specific patient reported outcome measure for patients with respiratory disease.

With Dr. Gordon Guyatt and other colleagues he has performed a number of methodological studies that focus on the minimal important difference (MID) and the use of clinical marker states in the assessment of quality of life. He convenes the Applicability and Recommendations Method Group of the Cochrane Collaboration, is co-chair of the GRADE working group and has chaired various guideline expert panels at the World Health Organization.

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