- Study protocol
- Open Access
A pilot study of yoga as self-care for arthritis in minority communities
Health and Quality of Life Outcomes volume 11, Article number: 55 (2013)
While arthritis is the most common cause of disability, non-Hispanic blacks and Hispanics experience worse arthritis impact despite having the same or lower prevalence of arthritis compared to non-Hispanic whites. People with arthritis who exercise regularly have less pain, more energy, and improved sleep, yet arthritis is one of the most common reasons for limiting physical activity. Mind-body interventions, such as yoga, that teach stress management along with physical activity may be well suited for investigation in both osteoarthritis and rheumatoid arthritis. Yoga users are predominantly white, female, and college educated. There are few studies that examine yoga in minority populations; none address arthritis. This paper presents a study protocol examining the feasibility and acceptability of providing yoga to an urban, minority population with arthritis.
In this ongoing pilot study, a convenience sample of 20 minority adults diagnosed with either osteoarthritis or rheumatoid arthritis undergo an 8-week program of yoga classes. It is believed that by attending yoga classes designed for patients with arthritis, with racially concordant instructors; acceptability of yoga as an adjunct to standard arthritis treatment and self-care will be enhanced. Self-care is defined as adopting behaviors that improve physical and mental well-being. This concept is quantified through collecting patient-reported outcome measures related to spiritual growth, health responsibility, interpersonal relations, and stress management. Additional measures collected during this study include: physical function, anxiety/depression, fatigue, sleep disturbance, social roles, and pain; as well as baseline demographic and clinical data. Field notes, quantitative and qualitative data regarding feasibility and acceptability are also collected. Acceptability is determined by response/retention rates, positive qualitative data, and continuing yoga practice after three months.
There are a number of challenges in recruiting and retaining participants from a community clinic serving minority populations. Adopting behaviors that improve well-being and quality of life include those that integrate mental health (mind) and physical health (body). Few studies have examined offering integrative modalities to this population. This pilot was undertaken to quantify measures of feasibility and acceptability that will be useful when evaluating future plans for expanding the study of yoga in urban, minority populations with arthritis.
In order for an intervention to be used, it must be acceptable to participants, and it must be feasible to administer. Acceptability can be defined as, “that quality which makes an object, person, event, or idea attractive or satisfactory” . Factors highly likely to be influential in shaping values and perceptions include ethnicity, nationality, culture, education, personality, and experience . The purpose of this pilot study is to investigate the feasibility and acceptability of offering a yoga intervention to the urban, minority population served by the National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS) Community Health Clinic (CHC) serving the Washington, DC area.
Previous studies using data from the 2002 National Health Interview Survey (NHIS)-Alternative Medicine Supplement found that yoga users were predominately white, female, and college educated with a mean age of 39.5 years . Among those reporting using yoga, 12% were black or Hispanic, 88% stated place of birth as the United States, and 27% used yoga for joint pain . There are a few studies in the literature that examine yoga in minority or diverse populations but none specifically address patients with rheumatic disease [5–7].
This study is a follow-up intervention to a descriptive, exploratory study, completed in 2004 by Wallen et al. (Clinical Trial# NCT00069342) which examined the diverse health beliefs and behaviors among a convenience sample of primarily African-American and Hispanic patients enrolled in the NIAMS Natural History of Rheumatic Disease in Minority Communities protocol [8–10]. Overall complementary and alternative medicine (CAM) usage was high, with pain relief listed as the primary reason. A little more than one-third (39%) of respondents stated that they were currently doing movement activity, and only 4.6% stated they were doing yoga .
Arthritis is highly prevalent in US adults, with approximately 50 million persons reporting doctor-diagnosed arthritis . Furthermore, arthritis is the nation’s most common cause of disability and is associated with considerable activity limitation, work disability and significant health care costs . The most common form of arthritis is osteoarthritis (OA), a slowly progressive joint disease that occurs when the joint cartilage breaks down. OA symptoms include joint pain, stiffness, knobby swelling, cracking noises with joint movements and decreased function. It typically affects the joints of the hands and spine and weight-bearing joints such as the hips and knees [14, 15]. Another form of arthritis is rheumatoid arthritis (RA), an autoimmune, chronic disease that causes pain, stiffness, swelling and limitations in the motion and function of multiple joints. While RA can affect any joint, the small joints in the hands and feet tend be involved more frequently than others [15, 16].
Arthritis disproportionally affects certain racial/ethnic minorities. The prevalence of arthritis is lower among blacks and Hispanics than among whites, but the impact is worse. Published analysis of racial/ethnic differences from the NHIS shows the prevalence of activity limitation, work limitation and severe joint pain are significantly higher among blacks, Hispanics, and multi-racial or “other” respondents than among whites [17, 18]. People with arthritis should be moving according to the American College of Rheumatology, the Arthritis Foundation and the Centers for Disease Control and Prevention (CDC) [19–21]. People with arthritis who exercise regularly have less pain, more energy, improved sleep and better day-to-day function. Yet, arthritis is one of the most common reasons people give for limiting physical activity and recreational pursuits . People with arthritis may have a difficult time being physically active because of symptoms and lack of confidence in knowing how much and what to do . Long-term studies have shown that people with inflammatory arthritis such as rheumatoid arthritis can benefit from moderate intensity, weight-bearing activity . According the CDC, physical activity can reduce pain and improve function, mobility, mood, and quality of life for most adults with many types of arthritis and recommends including activities that improve balance for people with arthritis who may be at risk for falling . According to the American College of Rheumatology, both range-of-motion (ROM) and stretching exercises help to maintain or improve the flexibility in affected joints and surrounding muscles. This contributes to better posture, reduced risk of injuries and improved function. They recommend activities such as yoga because it incorporates both ROM and stretching movements 
According to a report using the data from the 2002 NHIS, adults with arthritis are significantly less likely to engage in recommended levels of physical activity. In both men and women with arthritis, inactivity has been associated with older age, lower education, and having functional limitations. Access to a fitness facility was inversely associated with inactivity. Among women, inactivity was also associated with being Hispanic, non-Hispanic black, having frequent anxiety/depression or social limitations, needing special equipment to increase functional capacity, and not receiving physical activity counseling .
Yoga is an ancient system of relaxation, exercise, and healing with origins in Indian philosophy an estimated 5,000 years ago [24, 25]. It is regarded as a holistic approach to health reported to increase flexibility, strength, and stamina while also fostering self-awareness and feelings of well-being [26–33]. Yoga can be done anywhere, requires no special equipment, is gentle on the joints and can be modified for each person. It uses only gravity and the body itself as resistance, so it is a low-impact activity. However it is not just an exercise; it is a mind-body intervention. The combination of stress management and gentle physical activity is well suited for investigation in both osteoarthritis (OA) and inflammatory immune-mediated diseases such as rheumatoid arthritis (RA) .
Yoga is generally low-impact and safe for healthy people when practiced appropriately under the guidance of a well-trained instructor. Overall, those who practice yoga have a low rate of side effects, and the risk of serious injury from yoga is quite low . As with any physical activity based on the person undertaking the exercise, there may be contraindications or side effects which make a technique (such as postures or breath work) inadvisable [24, 25]. For example poses that put the head lower than the heart may lead to increases in cerebral and intraocular pressure; therefore, patients with high myopia or with hypertension, glaucoma, detachment of the retina, central retinal vein occlusion, discharging ears, or cervical spondylitis should avoid some inverted poses [24, 25]. Adverse events and case reports found in the literature were reviewed when preparing the protocol [3, 35–37]. However, related poses and techniques reported are not taught or encouraged as part of this protocol. All patients for this study are medically cleared to participate in light to moderate exercise before being recruited to participate.
According to the yogic literature, yoga can help correct the interconnected factors of dysfunctional movement patterns, lack of body awareness, and poor posture [15, 26, 38]. Yoga takes the whole body through a wide range of motion . Static stretching is the most common technique used in Hatha yoga; which includes both contracting muscles to stretch a target muscle, and when relaxing into a stretch using only body weight to stretch muscles . People with arthritis tend to avoid using sore joints because of the pain involved; inactivity weakens muscles and further decreases range of motion in the joints. Gentle movement taught by a skilled yoga therapist may help by keeping the body moving. Yoga may be suited to help prevent or minimize the erosion of cartilage that causes the joint pain of OA, to create greater ease of movement and decrease pain within joints that have already sustained damage . Most descriptions of the effect of yoga on musculoskeletal disorders point to the benefits of joint realignment and active stretch producing traction of muscles during the asanas (or yoga poses) .
A growing number of research studies have shown that the practice of yoga can improve posture, strength, endurance and flexibility [31, 41, 42]; improve balance, gait, and fear of falling [43–45], and hand grip strength . Other studies have shown that practicing yoga asanas (postures), meditation or a combination of the two, reduces pain for people with arthritis [47, 48]. Yoga postures and breath work (pranayama) have been shown to also help with physiological variables such as blood pressure, respiration, and heart rate [47–57]. For patients with arthritis, emphasis on stretching, strength, posture, balance, and the ability to adjust pace and intensity are important components of a safe activity, all of which yoga encompasses. Yoga interventions have been shown to produce improvements in quality-of-life measures related to sense of well-being, energy, and fatigue ; and to beneficially impact mood, depression and anxiety disorders [28–33]. Yoga has also been demonstrated to reduce the physical effects of stress [59, 60], by reducing the levels of cortisol [61–64]; and affecting the neuroendocrine system . Stress may play a role in worsening symptoms of OA, and contribute to flare-ups of inflammation in RA . There is promising evidence that yoga therapy may help both osteoarthritis and rheumatoid arthritis [25, 44, 66–75]. The most important limitations of the existing research regarding the impact of yoga are: lack of minority representation, inadequate sample size, overly broad age range, lack of specification regarding the tradition of yoga utilized, and lack of a theoretical model to inform treatment implementation and assessment of outcomes .
There are studies that report an interest of diverse minorities in complementary and alternative medicine (CAM)  and that CAM is most often used to treat a variety of musculoskeletal problems and conditions . The question to ask is, why not yoga? It is possible that culture plays an important role in the initiation of yoga use and other forms of physical activity. For example, one study found that Latina women’s physical activity depended on their degree of acculturation, expounding that for many the concept of “leisure time,” does not exist. And that middle-class Latinos work five extra hours per week compared with Anglo-Americans . Disparities in the use of yoga in minority groups (specifically low-income populations) could be related to the costs of attending classes. One of the most practiced CAM modalities is prayer, a practice that is financially accessible to all income levels [7, 47]. Given that yoga practice can be a fee-based service, it might be challenging for low-income populations to use this health modality. Geographical access to yoga classes may also be problematic for disadvantaged populations. However, a study by Wilson (2008) suggests that given access to yoga practices, diverse populations benefit from these practices, and anticipate using them in everyday life. Almost all participants in this study (98%) would recommend yoga practices to others .
The primary objective of this study is to determine the feasibility and acceptability of providing yoga to an urban, minority population with arthritis, using a proven yoga based intervention. The secondary objective is to determine the appropriateness of specific physical and psychosocial measures for this population, and intervention with a focus on physical function and patient reported measures. The tertiary objective is to determine the feasibility of using computerized self-interview (with assistance) to capture baseline and final status.
Assessments will be made from a convenience sample of 20 participants undergoing an 8-week program of yoga classes consisting of 60-minute sessions, twice a week. The yoga classes are designed especially for people with arthritis.
Research participants will be recruited from English-speaking or Spanish-speaking patients receiving care from the NIAMS rheumatology practice located in Silver Spring, Maryland, a racially diverse area in the Washington DC metro region. Rheumatology care is provided without regard to medical insurance status and patients are referred from other neighborhood health centers, clinics, or practices in the area Potter et al. . Data from the NIAMS Community Health Center (CHC) shows RA (28%) makes up the largest percentage of patients seen followed by OA (11%), and various other rheumatologic diagnoses .
Patients must meet all of the following criteria to be eligible for study admission. The Medical Advisory Investigator and nurse practitioner on the study will determine whether subjects meet the medical exclusion criteria:
Adult patients enrolled in the NIAMS Natural History of Rheumatic Disease in Minority Communities
Diagnosis of osteoarthritis (OA) or rheumatoid arthritis (RA)
Willingness and ability to provide informed consent
Age ≥ 18 years
Recent (less than 6 months) or planned joint surgery
Use of assistive ambulatory devices
Other significant medical or psychiatric conditions, including other inflammatory conditions
Hyper-mobility or unstable disease that could compromise participation in the study
In attempts to ascertain the initial interest in yoga classes as part of a research protocol, patients from the NIAMS CHC were interviewed in September 2010. Respondents requested to have classes available in both English and Spanish. A common fear expressed about yoga classes was of being required to do “pretzel poses”. Both respondents and NIAMS clinic staff expressed time commitment may be a barrier for this population, due to the need to work several jobs. Most respondents preferred to attend yoga classes from 6–12 weeks.
The study follows 20 participants over an 8-week series of yoga classes. Classes that include deep breathing, relaxation, meditation, poses for strength, flexibility, and balance are offered twice a week. Classes are taught by bilingual (English/Spanish), racially concordant yoga teachers and held at a yoga studio near the NIAMS CHC.
At baseline, demographic and clinical data are collected via a computerized in-person interview, conducted by trained interviewers (Figure 1). Patient reported outcomes, captured via a web-based questionnaire, are collected at both baseline and the end of the study. Physical measurements, also collected at baseline and the end of the study, are obtained by rehabilitation medicine. Field notes, quantitative and qualitative data regarding feasibility and acceptability are also collected during the course of the study.
For this pilot intervention, class size is kept small (5–10 participants) to allow for modifications and explanation of yoga poses that will encourage greater self and body awareness. The yoga therapy approach tailors each pose to the needs and limitations of every individual. Props (chairs, bolsters, blankets, blocks and straps) are used and the postures are modified to accommodate the limitations of the arthritis patients taking the yoga classes.
Participants are encouraged to develop a home practice, which appears to be critical to the effectiveness of the intervention . The last section of each class is dedicated to providing guidance on how to do home practice based on poses taught and information given during each yoga class. All participants receive a yoga mat, blocks, belt, and blanket for their home practice. Participants keep a journal to qualitatively document the frequency of home practice and their experience of participating in the study. Journals are open format, allowing respondents to record their observations/feelings about practicing yoga in their own words [81–84].
This study focuses on the branch of Hatha yoga that uses postures (asanas), breathing techniques (pranayama) and meditation. Within Hatha yoga, there are numerous styles each with a slightly different approach to the physical practice of yoga. This protocol is primarily influenced by the styles of Integral, Iyengar and Kripalu yoga, each of which is considered to focus on proper physical alignment in a gentle and attentive fashion, while also including a strong component of mindfulness during and between physical postures [15, 85].
The yoga classes are formatted so that every class builds on the previous class. The contents of class 1 are repeated with additional poses added during each successive class (Table 1).
This format follows that of the previous randomized research study Yoga for Arthritis, conducted through Johns Hopkins University, which explored mediators of yoga practice and health related quality of life measures and disease symptoms in RA and OA patients. Results from the study found benefits of this sixteen-class yoga series created specifically for those with arthritis included:
A statistically significant improvement in overall physical health, flexibility, and balance.
A significant reduction in symptoms of depression and improvement in positive affect.
A significant improvement in pain symptoms and, for those with RA, a significant difference in the number of tender and swollen joints when compared with control subjects receiving the usual medical care [86, 87].
Dr. Steffany Haaz, a researcher on the Hopkins study and an advanced yoga teacher trained in yoga therapy provided yoga for arthritis training to bilingual yoga instructors recruited to teach for this study. In order to optimize treatment fidelity, all instructors use the same training manual of 16-class sequence used in the Haaz study and all classes are videotaped. Class attendance, the name of yoga instructor, home practice, and reported side effects are recorded during each class session.
The primary aim of this pilot study is to attempt to quantify measures of feasibility and acceptability that will be useful when evaluating future plans for expanding the study of yoga in this population. There are a number of challenges in recruiting and retaining study participants in a community setting. We hypothesize that by providing bilingual materials, racially concordant images for recruitment materials, culturally similar investigators and yoga instructors, as well as an intervention created specifically for persons with arthritis; participants will be more willing to enroll, attend classes, and report a positive experience after completing the 8-week series.
The second aim of this study is to determine if the measures of well-being selected for this minority population are appropriate to discern facilitators and impediments for participants to view yoga as a viable option for self-care. Self-care has become increasingly important in being able to self-manage chronic disease states; however, many patients with chronic disease do not integrate self-management behaviors into their lives . The concept of well-being integrates mental health (mind) and physical health (body) resulting in more holistic approaches to disease prevention and health promotion . Well-being includes the presence of positive emotions and moods (e.g., contentment, happiness), and the absence of negative emotions (e.g., depression, anxiety), as well as aspects of physical, social, emotional, psychological well-being . It is associated with: self-perceived health, healthy behaviors, mental and physical illness, and social connectedness . For this study, self-care is defined as adopting behaviors (such as continuing to practice yoga) that improve physical and mental well-being and may decrease arthritis symptoms and side effects.
A revised model based on Bandura’s social cognitive theory (Figure 2) shows the paths of influence believed to be relevant for this study. Bandura’s (2004) theory suggests that self-efficacy plays an important role in motivating behavior change . Self-efficacy is the confidence in one’s personal ability to perform a task or behavior or to change a specific cognitive state, regardless of circumstances or contexts [91, 92]. Social cognitive theory specifies a core set of determinants, among which perceived self-efficacy and knowledge of perceived facilitators and impediments may lead to behavior changes [90, 93]. Ways to influence self-efficacy include learning a new behavior, seeing people similar to oneself succeed; social persuasion; reducing negative emotional states; and correcting misinterpretations of physical ability [90, 93]. The potential facilitators and impediments are measured at baseline and again at the end of the study to see if there are any changes after completing the intervention.
The third aim is to determine the feasibility of using computerized self-interview (with assistance) to capture baseline and final health status outcomes. The previous study in this population by Wallen was completed using an in-person paper-and-pencil interview questionnaire [9, 10]. In attempts to determine the feasibility for using a computerized system, this study uses a computer-assisted interview method with both the interviewer collecting baseline background information; and the respondent entering patient reported outcome measures directly into a web-based system, with assistance as needed.
Acceptability of this study will be evaluated based on the response rate, percent of classes completed, exit interview comments and the percent of patients continuing yoga after three months. Feasibility will be determined based on exit interview (see Appendix) comments and qualitative data. Qualitative field notes are kept to monitor/document related issues such as location, personnel, equipment, and the amount of modifications needed during yoga classes. Records are kept of eligible patients who decline and reasons for declining. Field notes are maintained by study investigators during recruitment, onsite yoga classes, and when interacting with study participants outside of completing questionnaires. An exit interview is completed after the last class. Those who may have dropped out of the study prior to the last class will be contacted by phone in attempts to complete the exit interview.
The feasibility of using a computerized self-interview method is based on the estimated amount of assistance needed to complete questionnaires (measured in increments from 0-100%), comments collected from the interviewer offering assistance, any technical problems encountered, and comments solicited from the participants during the exit interview.
Self-reported demographic variables include: gender, age, marital status, race/ethnicity, educational level and occupational status. Clinical variables related to arthritis and current practices include: rheumatic diagnosis, other diagnoses, weight, height, duration (years) of rheumatic disease and location current joint stiffness and pain location , current medications, heart rate and oxygen saturation level, exercise, diet and an Inventory of Complementary and Alternative Medicine Practices (ICAMP) created during the Wallen study . Acculturation is measured by obtaining the proxy measures of spoken English language proficiency, country of origin, and length of time in United States.
Health literacy is the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions. This study uses the Rapid Estimate of Adult Literacy in Medicine Short Form (REALM-SF) and Short Assessment of Health Literacy for Spanish Adults (SAHLSA-50) tools [95–98]. The REALM is an assessment tool using word recognition tests, which has high criterion validity when correlated with other literacy tests and has high test-retest and reliability 0.97 (p < .001) [96–98]. The REALM-SF is a 7-item word recognition test with scores that were highly correlated with the REALM in development (r = 0.95, p < 0.001) and validation (r = 0.94, p < 0.001) samples . The SAHLSA-50 is a validated health literacy assessment tool containing 50 items designed to assess a Spanish-speaking adult’s ability to read and understand common medical terms, based on REALM . The SAHLSA-50 correlated with the Test of Functional Health Literacy in Adults(r = 0.65); and displayed good internal reliability (Cronbach’s alpha = 0.92) and test-retest reliability (Pearson’s r = 0.86) .
Patient reported outcomes and psychosocial concepts
Patient reported outcomes are assessed at baseline and at the end of the 8-week yoga intervention, with bilingual staff available to help complete documentation and computer usage. In attempts to reduce participant burden, instead of using legacy measures, this study is using the Patient-Reported Outcomes Measurement System (PROMIS). The item databanks for PROMIS have been tested for reliability and comparability using Item-Response Theory; short forms were developed and compared with other well-validated and widely accepted (“legacy”) measures [102–104]. The PROMIS 29-profile was selected as a domain framework for self-reported health to look at eight domains: physical function, anxiety, depression, fatigue, sleep disturbance, satisfaction with social roles, pain interference, and pain intensity.
Self-care and well-being are evaluated using the Health-Promoting Lifestyle Profile II (HPLP-II), self-efficacy, self-rated health, class attendance, reports of continued practice yoga after completing the study intervention, as well as qualitative data (participant comments). The HPLP-II is a self-administered 52-item instrument that measures the frequency of self-reported healthy behaviors. It consists of 6 subscales: physical activity, spiritual growth, health responsibility, interpersonal relations, nutrition, and stress management. This is a 4-point Likert type scale with responses ranging from 1 (never) to 4 (routinely). The higher scores indicate the more frequent engagement in health behaviors . Callaghan (2003) reported the following Cronbach’s alpha coefficients of internal consistency reliability: total scale 0.93, health responsibility 0.83, physical activity 0.87, nutrition 0.76, spiritual growth 0.84, interpersonal relations 0.82, and stress management 0.75 . A randomized study of bilingual Hispanic individuals found the English- and Spanish-language versions of the HPLP II to have statistically acceptable levels of reliability and equivalency .
Self-efficacy is measured using Lorig’s self-efficacy in exercise, a 3-item scale used to measure confidence in exercising regularly based on a scale from 1 (not at all confident) to 10 (totally confident) . Higher scores indicate more confidence. Lorig et al.  and Wallen , have validated the 8-item Arthritis Self-Efficacy Scale (ASES) with similar populations, however the Haaz Yoga for Arthritis study  found no change when using the same ASES measure. For this pilot, the decision was made to focus specifically on using a measure related to exercise self-efficacy.
Self-rated health consists of a single response item, “Would you say your health in general is excellent, very good, good, fair, or poor?” . Lorig et al. (1996) found the mean rating for this item to be 3.29 (SD ± 0.91). In a subset of their sample (n = 51), this item displayed a test-retest reliability of .92 [108, 111]. This measure has been translated into Spanish . Self-rated/self-reported health (SRH) has been differentially reported by Hispanics compared to whites, especially based on their acculturation status [111–114]. Hispanics are 3.6 times more likely to report fair or poor health compared to whites .
Physical assessment -Clinical measures were selected to evaluate domains of balance (single leg stance, functional reach test) and functional mobility (timed up and go test) that may be responsive to change with an exercise intervention. These measures are evaluated both at baseline and after completing the series of yoga classes, by the National Institutes of Health (NIH) rehabilitation medicine staff associated with the study. The single leg stance (SLS) determines if the patient can stand on one leg for 10 seconds . When evaluated mean criterion-related validity was high (Pearson’s r =0.84, 0.83, respectively). Inter-observer reliability was high (ICC (2,1) = 0.81 at Test 1 and 0.82 at Test 2). Intra-observer reliability was high (on average ICC (2,1) = 0.88; Pearson’s r = 0.90) .
The functional reach test is a dynamic measure of stability during a self-initiated movement . Functional reach is the difference (in inches) between a person’s arm length and maximal forward reach with the shoulder flexed to 90 degrees while maintaining a fixed base of support in standing. In a study by Duncan (1990), it was found that functional reach measures were strongly associated with measurements of the center of pressure excursion. The Pearson correlation coefficient was 0.71 and the R2 using linear regression was 0.51. Analysis of the test-retest reliability of the three primary measures of postural control suggests that functional reach is highly reproducible. The intraclass correlation coefficient (ICC 1, 3) for center of pressure excursion was 0.52, electronic functional reach 0.81, and “yardstick” reach 0.92. .
The timed “Up and Go” test (TUG) measures, in seconds, the time taken by an individual to stand up from a standard arm chair, walk a distance of 3 meters, turn, walk back to the chair, and sit down . A history of arthritis increases the risk of falling, sensitivity of the TUG for predicting falls was 0.80 and specificity was 0.934 [121, 122]. Inter-rater reliability for the TUG is high with a same day, three-rater intra-class correlation coefficient (ICC) of various studies has ranged from 0.99 - 0.992. For validity, moderate to high correlations have been observed with scores on Berg Balance Scale, gait speed, stair climbing, and the Barthel Index of Activities of Daily Living Scale .
A timed floor transfer is a clinical test of strength, flexibility, function, and problem solving; it measures the time necessary to transfer from standing to the floor and return to standing in any way that participants are able . The time needed is recorded in seconds, then standardized by using body height to determine the speed of this task. Higher values indicate better scores . The interrater reliability for three timed tests (50-ft walk, five-step, and floor transfer) between various pairs of two testers was determined to be excellent (r = .99) . The calculated ICCs were moderately high (ICC2,1 = .79, p = .0001) on the timed data to determine test–retest reliability in a community-based, predominantly Hispanic population some of whom were diagnosed with arthritis .
Upper body ability is measured using the Disabilities of the Arm, Shoulder and Hand (DASH) Outcome Measure. The DASH is a 30 item self-report questionnaire designed to measure physical function and symptoms in patients with any or several musculoskeletal disorders of the upper limb. The DASH has been shown to have acceptable reliability and validity when assessing upper limb functional ability in RA populations . A study undertaken to evaluate the reliability, validity, and responsiveness of the DASH found it to correlate with other measures (r > 0.69) with a test-retest reliability of (ICC = 0.96) .
The study is a pilot convenience sample of 20 participants. Yoga classes will be held for as few as 5, or as many as 10 participants per class depending on how long it takes to accrue participants onto the study. Research participants are recruited from English-speaking or Spanish-speaking patients receiving care from the NIAMS CHC rheumatology practice.
Racially concordant images were used to develop pamphlets to be displayed in clinic and used for recruitment. All recruitment materials are available in both English and Spanish due to the large percentage (57%) of Latino/Hispanic patients seen by the NIAMS CHC (personal communication: Alice Fike MSN). Because of clinician’s concern regarding literacy, all documents are read to patients in either English or Spanish, when needed. Patients are referred to the Principal Investigator by the NIAMS rheumatology clinicians who are already familiar with their care. After full study explanation, either the Principal Investigator or Lead Associate Investigator obtain written informed consent in person at the rheumatology clinic.
Participant information will be collected using a computerized questionnaire during one-on-one sessions with either the Principal Investigator or Associate Investigators. Data will be collected electronically using the Clinical Trials Database (CTDB). CTDB is a web based application that is hosted at the NIH therefore data are housed on a dedicated in-house server protected according to federal standards. The security framework of CTDB and the clinical trials survey system (CTSS) permit only the Principal Investigator and designated Associate Investigators to have access to identified data in the database.
This pilot study evaluates the acceptability of offering yoga as an integrative intervention for self-care using the response rate, percent of classes completed, exit interview comments and the percent of patients continuing yoga after three months. Barriers and reasons for continuing/discontinuing yoga are assessed in a brief questionnaire either in person or by telephone, three (3) months after completing yoga classes. Results from the Haaz study were used to determine reasonable measure and time frames for this study. The study found of 102 patients screened, 52% of randomized persons completed the 8-week yoga session . Those who actually started the intervention were very likely to complete it, as attrition was highest prior to the first class . Based on these results, the decision was made to decrease the time from enrollment to start of yoga classes; and to decrease the class size to 5–10 participants per class.
Acceptability of this study will be evaluated based on the response rate, percent of classes completed, exit interview comments and the percent of patients continuing yoga after 3 months. Feasibility will be determined based on exit interview comments and qualitative data. Qualitative field notes will be kept to monitor/document related to issues such as site capability (location/space), personnel (bilingual yoga teachers/investigators), equipment (computers/yoga props), and the amount of modifications needed. A record will be kept of eligible patients who decline and reasons for declining.
Statistical Package for the Social Sciences (SPSS) Version 20.0 will be used to analyze outcome measure data. Descriptive statistics (mean and median) will be used to describe the profiles of the subjects from demographic data gathered. Wilcoxon tests will be used to test differences between baseline and final assessments, for those who complete the study. Pre- and post- changes will be identified; however, no attempt will be made to evaluate statistical significance given the small sample size of the pilot study. An attempt will be made to complete an exit interview for all participants, even those who discontinue participation in the study prior to full completion. Missing data will be managed according to the recommendations of selected measures used in the protocol, or omitted from analyses.
The feasibility of using a computerized self-interview method (with assistance) will be based on the percent of assistance needed to complete questionnaires, comments collected from the interviewer offering assistance and comments solicited from the participants during the exit interview.
The Medical Advisory Investigator (MAI) will be responsible for the patient safety monitoring. The Principal Investigator will provide a regular report of all protocol activities to the MAI and discuss any concerns. No invasive treatments are provided as part of this protocol. This population will not be exposed to yoga poses (i.e. headstands and shoulder stands) that are most commonly associated with injury. Adverse events and serious adverse events will be monitored at all times during yoga classes and if reported by subjects by telephone. Specific safety instructions will be given as part of every class and pose modifications will be taught to individuals as needed. Participants will be instructed to report side effects immediately should they occur.
Investigators will attend all yoga classes and will ask subjects about side effects during each class session. Subjects will also be instructed to report side effects immediately, to the study PI; by telephone should they occur while practicing at home. Any reported side effects will be documented by the investigators using the weekly flow sheet and reviewed daily by the PI. The PI will report adverse events to the MAI for recommendations and follow-up, and record in the patient record. For research related injury, the subject will be evaluated by NIAMS rheumatology at either the NIAMS CHC or the NIH Clinical Center.
A serious adverse event is defined as any untoward medical occurrences that 1) result in death, 2) are life-threatening, 3) require hospitalization, 4) cause persistent or significant disability/incapacity, 5) result in congenital anomalies or birth defects, 6) are other conditions which in the judgment of the Investigators represent significant hazards. All serious adverse events will be reported to the IRB and to the Clinical Director, within 7 days for death or life threatening adverse event and within 15 days for all others. All adverse events reported under this protocol will be limited to those events which are possibly, probably or definitely related to the research described in this protocol.
Under the Natural History protocol (Clinical Trial# NCT00024479), the reporting of adverse events will focus on adverse events that are related to the diagnostic and therapeutic interventions where the NIH is involved either directly or indirectly by recommending certain interventions. Adverse events associated with the natural history of rheumatic disease will not be reported. Adverse events associated with the yoga intervention will be monitored by the PI, serving as safety officer, and will be reported to the IRB as appropriate and as part of the annual report/renewal.
Approval to conduct the study was obtained through the National Institute of Diabetes and Digestive and Kidney Disease/National Institute of Arthritis and Musculoskeletal and Skin Disease’s intramural Institutional Review Board. Since the protocol approval, an amendment was submitted to include a Spanish consent, to obtain approval for a change in the location for offering the yoga classes and to add a yoga student manual for participants on the study. This amendment was approved on 6/4/2012. A second amendment was submitted during the continuing review process to remove one associate investigator and add three new investigators. This amendment was approved on approved 2/20/2013.
Consent is obtained by the Principal Investigator or Lead Associate Investigator. Once the study has been explained to subjects, including the objectives, time commitment and process, subjects are given the informed consent/assent document to review. Subjects are encouraged to ask questions prior to enrolling in this study. Subjects are reassured that participation in this study is entirely voluntary and that they may withdraw from the study at any time. Subjects are informed that their decision to participate in or withdraw from this study will impact neither their participation in other protocols for which they may be eligible, nor their ability to receive services at the Clinical Center that they may require.
Patient data including the results of physical function tests and responses to questionnaires are entered into an NIH-authorized and controlled research database. Any future research use will occur only after appropriate human subject protection institutional approval as prospective NIH IRB review and approval an exemption from the NIH Office of Human Subjects Research Protections. The Principal Investigator is responsible for overseeing entry of data into an in-house password protected electronic system and ensuring data accuracy, consistency and timeliness. The Principal Investigator, Associate Investigators and/or a contracted data manager will assist with the data management efforts.
All human subjects’ personally identifiable information as defined in accordance to the Health Insurance Portability and Accountability Act (HIPAA) will be separated from individual subject data. Protocol eligibility and consent verification will be tracked and separated from individual subject data. Primary data obtained during the conduct of the protocol will be kept in secure network drives that comply with NIH security standards. Primary and final analyzed data will have identifiers so that research data can be attributed to an individual human subject participant required for subject identification, e.g., study-specific identifying number generated by Principal Investigator and/or Associate Investigators for subject identification. The protocol and all primary and analyzed data will be stored in the NIH Clinical Center’s secure network. Clinical data will be collected using subjects’ names in the source document. However, clinical report forms will be coded. Research survey responses, will be maintained in a secure network password-protected database (Clinical Trials Database (CTDB)). Any printed records with identifier information will be kept in a locked file cabinet within a secure file cabinet of the PI.
Investigators will be responsible for collecting the questionnaires from subjects and ensuring the delivery of the data to the secure office of the Principal Investigator. Data from consenting subjects will be stored until they are no longer of scientific value or if a subject withdraws consent for their continued use, at which time they will be destroyed. Should we become aware that a major breach in our plan for tracking and storage of data has occurred, the IRB will be notified. Each NIH protocol undergoes a yearly departmental independent audit in addition to yearly continuing reviews by the IRB.
Since this protocol is federally funded, any manuscript to be published in a peer-reviewed journal will be submitted to PubMedCentral or public access upon acceptance for publication.
There are a number of challenges in recruiting and retaining participants from a community clinic serving minority populations. Few studies have examined offering integrative modalities to this population. This pilot was undertaken in order to quantify measures of feasibility and acceptability that will be useful when evaluating future plans for expanding the study of yoga in an urban, minority population with arthritis.
Previous studies of patients with arthritis suggest that taking yoga classes helps to improve measures of physical health, flexibility, balance, affect, and pain symptoms as well as reduces measures of depression. It is unclear what aspects of yoga as an intervention may or may not be acceptable to populations such as those served by the NIAMS CHC.
Knowledge gained from this pilot study will contribute to the understanding of the feasibility of this study design and the acceptability of yoga as self-care modality for minorities with arthritis. The design of the study will also add to the body of work related to the use of patient reported outcome measures and the use of computerized data collection methods within this population.
Appendix: yoga study exit interview
Thank you for participating in our study. We would like to ask you some questions as you are finishing the study. Please give your honest answers to help us improve our study. Your comments are very important to us.
1. We would like to ask about your experience using the laptop computer to complete the surveys throughout the study.
a. How comfortable were you using the laptop computer? Please circle the appropriate number below:
Very Comfortable 1 2 3 4 5 Very Uncomfortable Comfortable
b. Do you think we should continue use computers in this way?
c. Is there anything else you would like us to know about your experience using the computer to complete the surveys in this study?
2. Please give us your opinion on the yoga classes and location:
a. Overall, how satisfied were you with the yoga classes? Check one:
○ Completely satisfied
○ Mostly satisfied
○ Equally satisfied and dissatisfied
○ Mostly dissatisfied
○ Completely dissatisfied
b.How satisfied were you with the classroom where the classes were offered? Check one:
○ Completely satisfied
○ Mostly satisfied
○ Equally satisfied and dissatisfied
○ Mostly dissatisfied
○ Completely dissatisfied
3. How much do you agree or disagree with each of the following statements? Please circle one of the choices below.
(N).......Neither agree nor disagree
a. Yoga classes should be offered in English only
b. Yoga classes should be offered in both English and Spanish
c. I feel more comfortable taking yoga classes from teachers with diverse racial/ethnic backgrounds
d. prefer taking yoga classes with others who have arthritis
e. The yoga poses offered in class work well for people with arthritis
4. What did you like most about the yoga classes?
5. What did you like least about the yoga classes?
6. What changes would you make in the classes to make them more helpful to your arthritis?
7. Would you recommend yoga classes to a friend with arthritis?
8. Now that you have completed the study, do you see yoga as a way to care for your arthritis? Please check one of the circles below and answer the following questions.
○ Yes –please tell us why you see yoga as a way to care for your arthritis.
○ No – please tell us why you do not see yoga as a way to care for your arthritis.
9. How likely do you think it is that you would take another yoga class? Check one:
○ Extremely likely
○ Fairly likely
○ Somewhat likely
○ Slightly likely
○ Not at all*
*If you answered “not at all” above, please tell us why (for example: cost too much, too far away, don’t have time, no longer interested in yoga).
10. How likely do you think it is that you would practice yoga on your own now? Check one:
○ Extremely likely
○ Fairly likely
○ Somewhat likely
○ Slightly likely
○ Not at all*
*If you answered “not at all” above, please tell us why (for example: do not have time, no longer interested in yoga).
Arthritis self-efficacy scale
Complementary and alternative medicine
Centers For Disease Control And Prevention
Community health center
Disabilities of the arm, shoulder and hand
Health-Promoting Lifestyle Profile II
Inventory of complementary and alternative medicine practices
Intraclass correlation coefficients
National Institutes Of Health
National Health Interview Survey
National institute of arthritis and musculoskeletal and skin diseases
Patient-Reported Outcomes Measurement System
Rapid estimate of adult literacy in medicine - short form
Short assessment of health literacy for Spanish adults −50
Single leg stance
Self rated health
Timed “Up and Go” test.
Marshall JF: Acceptability of fertility regulating methods: designing technology to fit people. Prev Med 1977,6(1):65–73. 10.1016/0091-7435(77)90005-6
Winikoff B: Acceptability of first-trimester medical abortion. In Meeting of Scientific Group on Medical Methods for Termination of Pregnancy. Geneva: World Health Organization; 1994:1–32.
Birdee GS, Legedza AT, Saper RB, Bertisch SM, Eisenberg DM, Phillips RS: Characteristics of yoga users: results of a national survey. J Gen Intern Med 2008,23(10):1653–1658. 10.1007/s11606-008-0735-5
Bertisch SM, Wee CC, Phillips RS, McCarthy EP: Alternative mind-body therapies used by adults with medical conditions. J Psychosom Res 2009,66(6):511–519. 10.1016/j.jpsychores.2008.12.003
Haber D: Yoga as a preventive health care program for white and black elders: an exploratory study. Int J Aging Hum Dev 1983,17(3):169–176. 10.2190/HU5C-32FH-APVU-N6FY
Saper RB, Sherman KJ, Cullum-Dugan D, Davis RB, Phillips RS, Culpepper L: Yoga for chronic low back pain in a predominantly minority population: a pilot randomized controlled trial. Altern Ther Health Med 2009,15(6):18–27.
Wilson A, Marchesiello K, Khalsa SB: Perceived benefits of Kripalu yoga classes in diverse and underserved populations. International Journal of Yoga Therapy 2008,18(1):65–71.
Middleton KR, Wallen GR, Rivera-Goba M, Mittleman B: A description of self-efficacy, depression, pain, disability and CAM usage among minorities with rheumatic diseases. San Diego, CA: Society of Behavioral Medicine’s 29th Annual Meeting and Scientific Sessions; 2008.
Wallen GR, Middleton KR, Rivera-Goba MV, Mittleman BB: Validating English- and Spanish-language patient-reported outcome measures in underserved patients with rheumatic disease. Arthritis Res Ther 2011,13(1):R1. 10.1186/ar3219
Wallen GR, Middleton KR, Miller-Davis C, Tataw-Ayuketah G, Todaro A, Rivera-Goba M, Mittleman BB: Patients’ and community leaders’ perceptions regarding conducting health behavior research in a diverse, urban clinic specializing in rheumatic diseases. Prog Community Health Partnersh 2012,6(4):405–415. 10.1353/cpr.2012.0052
Middleton KR, Wallen GR: Assessing complementary and alternative medicine usage in disease specific minority patients. Denver, CO: American Public Health Association 138th Annual Meeting and Exposition; 2010.
Cheng YJ, Hootman JM, Murphy LB, Langmaid GA, Helmick CG: Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation –- United States, 2007–2009. Morb Mortal Wkly Rep 2010,59(39):1261–1265.
Furner SE, Hootman JM, Helmick CG, Bolen J, Zack MM: Health-related quality of life of U.S. Adults with arthritis: analysis of data from the behavioral risk factor surveillance system, 2005, and 2007. Arthritis Care Res 2003, 2011: 788–799.
McCall T: Yoga as medicine: The yogic prescription for health and healing. 1st edition. New York: Bantam Dell; 2007.
Rheumatoid arthritis. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/ra.asp
Bolen J, Schieb L, Hootman JM, Helmick CG, Theis K, Murphy LB, Langmaid G: Differences in the prevalence and severity of arthritis among racial/ethnic groups in the United States, National Health Interview Survey, 2002, 2003, and 2006. Prev Chronic Dis 2010,7(3):A64.
NHIS arthritis surveillance. http://www.cdc.gov/arthritis/data_statistics/national_nhis.htm#physical
Introduction to exercise. http://www.arthritis.org/exercise-intro.php
Move your body and fight arthritis. http://www.rheumatology.org/about/newsroom/2010/2010_01_23.asp
Physical activity and arthritis. http://www.cdc.gov/arthritis/pa_overview.htm
Practice management: Exercise and arthritis. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/exercise.asp
Shih M, Hootman JM, Kruger J, Helmick CG: Physical activity in men and women with arthritis national health interview survey, 2002. Am J Prev Med 2006,30(5):385–393. 10.1016/j.amepre.2005.12.005
Yoga for health: An introduction. http://nccam.nih.gov/health/yoga/introduction.htm
Mehta S, Mehta M, Mehta S: Yoga: The Iyengar way. 1st edition. London: Alfred A. Knopf, Inc.; 1990.
Garfinkel M, Schumacher RH Jr: Yoga. Rheumatic Disease Clinics of North America 2000,26(1):125–132. 10.1016/S0889-857X(05)70126-5
Arias AJ, Steinberg K, Banga A, Trestman RL: Systematic review of the efficacy of meditation techniques as treatments for medical illness. J Altern Complement Med 2006,12(8):817–832. 10.1089/acm.2006.12.817
Streeter CC, Jensen JE, Perlmutter RM, Cabral HJ, Tian H, Terhune DB, Ciraulo DA, Renshaw PF: Yoga asana sessions increase brain GABA levels: a pilot study. J Altern Complement Med 2007,13(4):419–426. 10.1089/acm.2007.6338
Wood C: Mood change and perceptions of vitality: a comparison of the effects of relaxation, visualization and yoga. J R Soc Med 1993,86(5):254–258.
Goyeche J, Ago Y, Ikemi Y: Asthma: The yoga perspective. Part I. The somatopsychic imbalance in asthma: Towards a holistic therapy. J Asthma Res 1980,17(3):111–121. 10.3109/02770908009105671
Krishnamurthy MN, Telles S: Assessing depression following two ancient indian interventions: effects of yoga and ayurveda on older adults in a residential home. J Gerontol Nurs 2007,33(2):17–23.
Pilkington K, Kirkwood G, Rampes H, Richardson J: Yoga for depression: the research evidence. J Affect Disord 2005,89(1–3):13–24.
Haaz S, Bartlett SJ: Yoga for arthritis: a scoping review. Rheumatic Disease Clinics of North America 2011, 37: 33–46. 10.1016/j.rdc.2010.11.001
Patel SC, Parker DA: Isolated rupture of the lateral collateral ligament during yoga practice: a case report. The Journal of Bone & Joint Surgery 2008,16(3):378–380.
Hanus SH, Homer TD, Harter DH: Vertebral artery-occlusion complicating yoga exercises. Arch Neurol 1977,34(9):574–575. 10.1001/archneur.1977.00500210076015
Walker M, Meekins G, Hu SC: Yoga neuropathy. A snoozer. Neurologist 2005,11(3):176–178. 10.1097/01.nrl.0000159986.75426.d5
Fishman L, Saltonstall E: Yoga for arthritis. New York: W.W. Norton & Company, Inc; 2008.
Long R: Scientific keys volume I: the key muscles of hatha yoga. 3rd edition. Bandha: Yoga; 2006.
Nayak NN, Shankar K: Yoga: a therapeutic approach. Phys Med Rehabil Clin N Am 2004,15(4):783–798. 10.1016/j.pmr.2004.04.004
Madanmohan , Mahadevan SK, Balakrishnan S, Gopalakrishnan M, Prakash ES: Effect of six weeks yoga training on weight loss following step test, respiratory pressures, handgrip strength and handgrip endurance in young healthy subjects. Indian J Physiol Pharmacol 2008,52(2):164–170.
Cowen VS, Adams TB: Physical and perceptual benefits of yoga asana practice: results of a pilot study. J Bodyw Mov Ther 2005,9(3):211–219. 10.1016/j.jbmt.2004.08.001
Schmid AA, Van Puymbroeck M, Koceja DM: Effect of a 12-week yoga intervention on fear of falling and balance in older adults: a pilot study. Arch Phys Med Rehabil 2010,91(4):576–583. 10.1016/j.apmr.2009.12.018
Bosch PR, Traustadottir T, Howard P, Matt KS: Functional and physiological effects of yoga in women with rheumatoid arthritis: a pilot study. Altern Ther Health Med 2009,15(4):24–31.
Ulger O, Yagli NV: Effects of yoga on balance and gait properties in women with musculoskeletal problems: a pilot study. Complement Ther Clin Pract 2011,17(1):13–15. 10.1016/j.ctcp.2010.06.006
Madanmohan , Thombre D, Balakumar B, Nambinarayanan T, Thakur S, Krishnamurthy N, Chandrabose A: Effect of yoga training on reaction time, respiratory endurance and muscle strength. Indian J Physiol Pharmacol 1992,36(4):229–233.
Barnes P, Powell-Griner E, McFann K, Nahin R: Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004, 343: 1–19.
Blumenthal JA, Emery CF, Madden DJ, George LK, Coleman RE, Riddle MW, McKee DC, Reasoner J, Williams RS: Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women. J Gerontol 1989,44(5):M147-M157. 10.1093/geronj/44.5.M147
Raub JA: Psychophysiologic effects of hatha yoga on musculoskeletal and cardiopulmonary function: a literature review. J Altern Complement Med 2002,8(6):797–812. 10.1089/10755530260511810
Sunkaria R, Kumar V, Saxena S: A comparative study on spectral parameters of HRV in yogic and non-yogic practitioners. International Journal of Medical Engineering and Informatics 2010,2(1):1–14. 10.1504/IJMEI.2010.029800
Jain S, Jain M, Sharma CS: Effect of yoga and relaxation techniques on cardiovascular system. Indian J Physiol Pharmacol 2010,54(2):183–185.
Telles S, Nagarathna R, Nagendra HR, Desiraju T: Physiological changes in sports teachers following 3 months of training in yoga. Indian J Med Sci 1993,47(10):235–238.
Konar D, Latha R, Bhuvaneswaran JS: Cardiovascular responses to head-down-body-up postural exercise (Sarvangasana). Indian J Physiol Pharmacol 2000,44(4):392–400.
Sivasankaran S, Pollard-Quintner S, Sachdeva R, Pugeda J, Hoq SM, Zarich SW: The effect of a six-week program of yoga and meditation on brachial artery reactivity: Do psychosocial interventions affect vascular tone. Clin Cardiol 2006,29(9):393–398. 10.1002/clc.4960290905
Selvamurthy W, Sridharan K, Ray US, Tiwary RS, Hegde KS, Radhakrishan U, Sinha KC: A new physiological approach to control essential hypertension. Indian J Physiol Pharmacol 1998,42(2):205–213.
Raju PS, Prasad KV, Venkata RY, Murthy KJ, Reddy MV: Influence of intensive yoga training on physiological changes in 6 adult women: A case report. J Altern Complement Med 1997,3(3):291–295. 10.1089/acm.1997.3.291
Ashok C: Impact of asanas and pranayama on blood oxygen saturation level. Br J Sports Med 2010,44(Suppl 1):i69.
Oken BS, Zajdel D, Kishiyama S, Flegal K, Dehen C, Haas M, Kraemer DF, Lawrence J, Leyva J: Randomized, controlled, six-month trial of yoga in healthy seniors: Effects on cognition and quality of life. Altern Ther Health Med 2006,12(1):40–47.
Pandya DP, Vyas VH, Vyas SH: Mind-body therapy in the management and prevention of coronary disease. Compr Ther 1999,25(5):283–293. 10.1007/BF02944271
Bera TK, Gore MM, Oak JP: Recovery from stress in two different postures and in Shavasana–A yogic relaxation posture. Indian J Physiol Pharmacol 1998,42(4):473–478.
Banasik J, Williams H, Haberman M, Blank SE, Bendel R: Effect of Iyengar yoga practice on fatigue and diurnal salivary cortisol concentration in breast cancer survivors. J Am Acad Nurse Pract 2011,23(3):135–142. 10.1111/j.1745-7599.2010.00573.x
Curtis K, Osadchuk A, Katz J: An eight-week yoga intervention is associated with improvements in pain, psychological functioning and mindfulness, and changes in cortisol levels in women with fibromyalgia. Journal of Pain Research 2011, 4: 189–201.
Kamei T, Toriumi Y, Kimura H, Ohno S, Kumano H, Kimura K: Decrease in serum cortisol during yoga exercise is correlated with alpha wave activation. Percept Mot Skills 2000,90(3 Pt 1):1027–1032.
West J, Otte C, Geher K, Johnson J, Mohr DC: Effects of Hatha yoga and African dance on perceived stress, affect, and salivary cortisol. Ann Behav Med 2004,28(2):114–118. 10.1207/s15324796abm2802_6
Devi SK, Chansouria JPN, Malhotra OP, Udupa KN: Certain neuroendocrine responses following the practice of Kundalini yoga. Alternative Medicine 1986,1(3):247–255.
Bukowski EL, Conway A, Glentz LA, Kurland K, Galantino ML: The effect of iyengar yoga and strengthening exercises for people living with osteoarthritis of the knee: a case series. Int Q Community Health Educ 2006,26(3):287–305. 10.2190/IQ.26.3.f
Garfinkel MS, Schumacher HR Jr, Husain A, Levy M, Reshetar RA: Evaluation of a yoga based regimen for treatment of osteoarthritis of the hands. J Rheumatol 1994,21(12):2341–2343.
Kolasinski SL, Garfinkel M, Tsai AG, Matz W, Van Dyke A, Schumacher HR: Iyengar yoga for treating symptoms of osteoarthritis of the knees: a pilot study. J Altern Complement Med 2005,11(4):689–693. 10.1089/acm.2005.11.689
Taibi DM, Vitiello MV: A pilot study of gentle yoga for sleep disturbance in women with osteoarthritis. Sleep Med 2011,12(5):512–517. 10.1016/j.sleep.2010.09.016
Badsha H, Chhabra V, Leibman C, Mofti A, Kong KO: The benefits of yoga for rheumatoid arthritis: Results of a preliminary, structured 8-week program. Rheumatol Int 2009,29(12):1417–1421. 10.1007/s00296-009-0871-1
Evans S, Moieni M, Taub R, Subramanian SK, Tsao JC, Sternlieb B, Zeltzer LK: Iyengar yoga for young adults with rheumatoid arthritis: results from a mixed-methods pilot study. J Pain Symptom Manage 2010,39(5):904–913. 10.1016/j.jpainsymman.2009.09.018
Haslock I, Monro R, Nagarathna R, Nagendra HR, Raghuram NV: Measuring the effects of yoga in rheumatoid arthritis. Br J Rheumatol 1994,33(8):787–788.
Telles S, Naveen KV, Gaur V, Balkrishna A: Effect of one week of yoga on function and severity in rheumatoid arthritis. Biomed Central Research Notes 2011, 4: 118.
Haaz S, Bartlett S, Bathon J: Initial findings of an RCT of yoga on physical and psychological functioning in RA and OA. Boston, Massachusetts: American College of Rheumatology; 2007.
Ebnezar J, Nagarathna R, Bali Y, Nagendra HR: Effect of an integrated approach of yoga therapy on quality of life in osteoarthritis of the knee joint: a randomized control study. International Journal of Yoga 2011,4(2):55–63. 10.4103/0973-6131.85486
Evans S, Subramanian S, Sternlieb B: Yoga as treatment for chronic pain conditions: a literature review. International Journal on Disability and Human Development 2008,7(1):25–32.
Barnes PM, Bloom B, Nahin RL: Complementary and alternative medicine use among adults and children: United States, 2007 (National health statistics reports no.12). Hyattsville, MD: National Center for Health Statistics; 2008.
Marquez D, McAuley E: Gender and acculturation influences on physical activity in Latino adults. nn . Behav Med 2006,31(2):138–144. 10.1207/s15324796abm3102_5
Potter J, Odutola J, Gonzales CA, Ward MM: Validation of English and Spanish-language versions of a screening questionnaire for rheumatoid arthritis in an underserved community. The Journal of Rheumatology 2008,35(8):1545–1549.
Fike A: NIAMS Community Health Clinic Demographics (6/2008–6/2011). 2011.
Verbrugge L: Health Diaries. Med Care 1980,18(1):73–95. 10.1097/00005650-198001000-00006
Richardson A: The health diary: An examination of its use as a data collection method. J Adv Nurs 1994, 19: 782–791. 10.1111/j.1365-2648.1994.tb01151.x
Stone AA, Shiffman S, Schwartz JE, Broderick JE, Hufford MR: Patient non-compliance with paper diaries. Br Med J 2002,324(7347):1193–1194. 10.1136/bmj.324.7347.1193
Burman M: Health diaries in nursing research and practice. Image Journal of Nursing Scholarship 1995,27(2):147–152. 10.1111/j.1547-5069.1995.tb00839.x
Garfinkel M: Yoga as a complementary therapy. Geriatrics and Aging 2006,9(3):190–194.
Yoga helpful for rheumatoid arthritis. http://www.arthritis.org/yoga-ra-08.php
Haaz S, Bingham C, Bathon J, Bartlett S: Joint Tenderness and Swelling in RA Patients with Participation Modified Yoga Program. San Diego, CA: American Public Health Association; 2008.
Marks R, Allegrante JP: A review and synthesis of research evidence for self-efficacy-enhancing interventions for reducing chronic disability: Implications for health education practice (Part II). In: Health Promotion Practice. vol. 2005, 6: 148–156. 10.1177/1524839904266792
Health-Related Quality of Life(HRQOL). http://www.cdc.gov/hrqol/wellbeing.htm
Bandura A: Health promotion by social cognitive means. Health Educ Behav 2004,31(2):143–164. 10.1177/1090198104263660
Bandura A: Self-efficacy: Toward a unifying theory of behavioral change. Psychol Rev 1977,84(2):191–215.
Bandura A: Self-efficacy: The exercise of control. 1st edition. W.H. Freeman & Company; 1997.
Bandura A: Health promotion from the perspective of Social Cognitive Theory. Psychology & Health 1998,13(4):623–649. 10.1080/08870449808407422
Multidimensional Health Assessment Questionnaire (MDHAQ). http://mdhaq.org/Public/Questionnaires.aspx
Health literacy interventions and outcomes: An updated systematic review. http://www.ahrq.gov/clinic/tp/lituptp.htm
Committee on Health Literacy: Health literacy: A prescription to end confusion. 1st edition. Washington, DC: The National Academies Press; 2004.
Davis TC, Michielutte R, Askov EN, Williams MV, Weiss BD: Practical assessment of adult literacy in health care. Health Educ Behav 1998,25(5):613–624. 10.1177/109019819802500508
Davis TC, Long SW, Jackson RH, Mayeaux EJ, George RB, Murphy PW, Crouch MA: Rapid estimate of adult literacy in medicine: A shortened screening instrument. Fam Med 1993,25(6):391–395.
Arozullah AM, Yarnold PR, Bennett CL, Soltysik RC, Wolf MS, Ferreira RM, Lee SY, Costello S, Shakir A, Denwood C: Development and validation of a short-form, rapid estimate of adult literacy in medicine. Med Care 2007,45(11):1026–1033. 10.1097/MLR.0b013e3180616c1b
Health literacy measurement tools. http://www.ahrq.gov/professionals/quality-patient-safety/quality-resources/literacy/sahlsatool.html
Lee SY, Bender DE, Ruiz RE, Cho YI: Development of an easy-to-use Spanish Health Literacy test. Health Serv Res 2006,41(4 Pt 1):1392–1412.
Cella D, Riley W, Stone A, Rothrock N, Reeve B, Yount S, Amtmann D, Bode R, Buysse D, Choi S: The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008. Journal of Clinical Epidemiology 2010,63(11):1179–1194. 10.1016/j.jclinepi.2010.04.011
Dynamic tools to measure health outcomes from the patient perspective. http://www.nihpromis.org/default.aspx
Walker SN, Hill-Polerecky DM: Psychometric evaluation of the Health-Promoting Lifestyle Profile II. Nebraska: University of Nebraska Medical Center; 1996.
Callaghan DM: Health-promoting self-care behaviors, self-care self-efficacy, and self-care agency. Nurs Sci Q 2003,16(3):247–254. 10.1177/0894318403016003016
Carlson ED: A case study in translation methodology using the Health-Promotion Lifestyle Profile II. Public Health Nurs 2000,17(1):61–70. 10.1046/j.1525-1446.2000.00061.x
Lorig K, Stewart A, Ritter P, Gonzalez V, Laurent D, Lynch J: Outcome measures for health education and other health care interventions. Thousand Oaks, Ca: SAGE Publications, Inc.; 1996.
Gonzalez VM, Stewart A, Ritter PL, Lorig K: Translation and Validation of Arthritis Outcome Measures Into Spanish. Arthritis and Rheumatism 1995,38(10):1429–1446. 10.1002/art.1780381010
Haaz S: Examining the safety, feasibility and efficacy of yoga for persons with arthritis. In Doctoral disseration. Baltimore: Proquest LLC; 2010.
Self-rated health. http://patienteducation.stanford.edu/research/generalhealth.html
Idler EL, Benyamini Y: Self-rated health and mortality: A review of twenty-seven community studies. J Health Soc Behav 1997,38(1):21–37. 10.2307/2955359
McGee DL, Liao Y, Cao G, Cooper RS: Self-reported health status and mortality in a multiethnic US cohort. Am J Epidemiol 1999,149(1):41–46. 10.1093/oxfordjournals.aje.a009725
Johnson KL, Carroll JF, Fulda KG, Cardarelli K, Cardarelli R: Acculturation and self-reported health among Hispanics using a socio-behavioral model: The North Texas Healthy Heart Study. Biomed Central Public Health 2010, 10: 53. 10.1186/1472-6963-10-53
Shetterly SM, Baxter J, Mason LD, Hamman RF: Self-rated health among Hispanic vs non-Hispanic white adults: The San Luis Valley Health and Aging Study. Am J Public Health 1996,86(12):1798–1801. 10.2105/AJPH.86.12.1798
Billek B: Objective measures of postural stability. In Unpublished Master’s thesis. Pittsburgh, PA: University of Pittsburgh; 1990.
Haupstein T, Goldie P: Visual judgements of steadiness in one-legged stance: Reliability and validity. Physiother Res Int 2000,5(3):141–156. 10.1002/pri.195
Whitney SL, Poole JL, Cass SP: A review of balance instruments for older adults. The American Journal of Occupational Therapy 1998,52(8):666–671. 10.5014/ajot.52.8.666
Duncan PW, Weiner DK, Chandler J, Studenski S: Functional reach: A new clinical measure of balance. J Gerontol 1990,45(6):M192–197. 10.1093/geronj/45.6.M192
Podsiadlo D, Richardson S: The Timed "Up and Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 1991, 39: 142–148.
Schwartz A, Villa M, Prill M, Kelsey J, Galinus J, Delay R, Nevitt M, Bloch D, Marcus R, Kelsey J: Falls in older Mexican-American women. J Am Geriatr Soc 1999,41(11):1371–1378.
Tinetti ME, Lui WL, Claus EB: Predictors and prognosis of inability to get up after falls among elderly persons. Journal of the American Medical Association 1993,269(1):65–70. 10.1001/jama.1993.03500010075035
Wang CY, Olson SL, Protas EJ: Physical-performance tests to evaluate mobility disability in community-dwelling elders. Journal of Aging and Physical Activity 2005,13(2):184–197.
Murphy MA, Olson SL, Protas EJ, Overby AR: Screening for falls in community-dwelling elderly. Journal of Aging and Physical Activity 2003,11(1):66–80.
Adams J, Burridge J, Mullee M, Hammond A, Cooper C: Correlation between upper limb functional ability and structural hand impairment in an early rheumatoid population. Clin Rehabil 2004,18(4):405–413. 10.1191/0269215504cr732oa
Beaton DE, Katz JN, Fossel AH, Wright JG, Tarasuk V, Bombardier C: Measuring the whole or the parts? Validity, reliability, and responsiveness of the Disabilities of the Arm, Shoulder and Hand outcome measure in different regions of the upper extremity. J Hand Ther 2001,14(2):128–146. 10.1016/S0894-1130(01)80043-0
Bingham HS III, Bartlett CO, Susan J: Adherence to an 8-week yoga program for RA and OA: Who drops out and why. In Arthritis Rheum. vol. 60. Baltimore, Maryland: ; 2009:1978.
Moonaz S: Perspectives from a yoga researcher and therapist. Presentation given at NIH 2010.
The study was supported in part by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Many thanks to Regina Andrade, BA; Li Yang, MS; NIAMS Community Health Center staff; and research participants.
The authors declare that they have no competing interests.
KM and GW and are accountable for data acquisition and preparation of the manuscript. KM, GW and MW designed the study. All authors contributed to the writing and preparation of the study protocol, excerpts of which were used in creating this manuscript. All authors have read and approved the final manuscript.
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Middleton, K.R., Ward, M.M., Haaz, S. et al. A pilot study of yoga as self-care for arthritis in minority communities. Health Qual Life Outcomes 11, 55 (2013) doi:10.1186/1477-7525-11-55
- Complementary and alternative medicine
- Rheumatoid arthritis