The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial

Table 5 Comparison between cancer survivors exercise group and cancer survivors control group in the psychological parameters - EORTC QLQ - BR23 from baseline to nine months of combined training

Variables	Exercise Group (N = 18)				Control Group (N = 18)				Time p	Group p	Time x group interaction p	Size effect Cohen’d
Variables	Baseline Mean ± SD	3 months Mean ± SD	6 months Mean ± SD	9 months Mean ± SD	Baseline Mean ± SD	3 months Mean ± SD	6 months Mean ± SD	9 months Mean ± SD	Time p	Group p	Time x group interaction p	Size effect Cohen’d
Body image	77.4 ± 14.7	87.7 ± 18.9	98.1 ± 3.6*^a	97.1 ± 7.2*^a	73.9 ± 17.8	78.9 ± 15.4	85.6 ± 19.5	73.3 ± 24.8	0.001	0.006	0.01	1.30
Sexual functioning	89.2 ± 16.6	91.2 ± 22.1	87.2 ± 18.2	94.1 ± 14.4	85.6 ± 26.6	90.0 ± 18.7	86.7 ± 22.0	94.4 ± 14.9	0.31	0.96	0.77	0.02
Sexual enjoyment	88.2 ± 28.7	88.3 ± 29.0	78.4 ± 26.2	86.3 ± 26.5	93.3 ± 13.8	95.6 ± 17.2	95.6 ± 17.2	93.3 ± 18.7	0.66	0.41	0.16	0.31
Future Perspective	54.9 ± 38.9	47.1 ± 37.4	74.5 ± 27.7	78.4 ± 37.1	55.5 ± 44.8	57.8 ± 36.6	55.6 ± 34.9	46.6 ± 43.3	0.34	0.05	0.28	0.79
Systemic therapy side effects	28.3 ± 15.7	12.0 ± 14.9	7.8 ± 12.7	16.5 ± 14.4	34.7 ± 24.8	20.1 ± 22.5	18.7 ± 15.8	22.1 ± 13.1	< 0.001	0.86	0.08	0.41
Breast symptoms	11.3 ± 12.1	4.4 ± 7.8	10.8 ± 14.9	10.3 ± 12.7	14.9 ± 21.5	16.2 ± 19.2	10.1 ± 18.2	11.3 ± 13.3	0.72	0.25	031	0.08
Arm symptoms	20.3 ± 19.7	12.4 ± 18.4	16.9 ± 28.8	18.9 ± 15.1	27.8 ± 32.8	27.8 ± 32.8	18.2 ± 21.6	24.6 ± 21.7	0.58	0.53	0.23	0.30
Upset by hair loss	27.4 ± 39.5	9.8 ± 25.7^a	5.9 ± 13.1*^a	17.6 ± 33.6	38.1 ± 43.1	23.8 ± 42.2	30.9 ± 33.2	33.3 ± 34.4	0.18	0.80	0.03	0.46

Note: Post hoc analysis time x group interaction: * = statistically significant difference between groups and ^a = Bonferroni’s post hoc with p < 0.05 compared to baseline. Values expressed as mean and standard deviation

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