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  1. The PGWBI is a 22-item health-related Quality of Life (HRQoL) questionnaire developed in US which produces a self-perceived evaluation of psychological well-being expressed by a summary score. The PGWBI has be...

    Authors: Enzo Grossi, Nicola Groth, Paola Mosconi, Renata Cerutti, Fabio Pace, Angelo Compare and Giovanni Apolone
    Citation: Health and Quality of Life Outcomes 2006 4:88
    Content type: Research Published on:

  2. To determine the clinimetric properties of two questionnaires assessing symptoms (Symptom Severity Scale) and physical functioning (hand and finger function subscale of the AIMS2) in a Dutch primary care popul...

    Authors: Marinda N Spies-Dorgelo, Caroline B Terwee, Wim AB Stalman and Daniëlle AWM van der Windt
    Citation: Health and Quality of Life Outcomes 2006 4:87
    Content type: Research Published on:

  3. Recent research has suggested that chronic dry mouth affects the day-to-day lives of older people living in institutions. The condition has usually been considered to be a feature of old age, but recent work b...

    Authors: W Murray Thomson, Herenia P Lawrence, Jonathan M Broadbent and Richie Poulton
    Citation: Health and Quality of Life Outcomes 2006 4:86
    Content type: Research Published on:

  5. Research on quality and satisfaction with care during palliative chemotherapy in oncology patients has been limited. The objective was to assess the association between patient's satisfaction with care and sym...

    Authors: Vivian E von Gruenigen, Jessica R Hutchins, Anne Marie Reidy, Heidi E Gibbons, Barbara J Daly, Elisa M Eldermire and Nancy L Fusco
    Citation: Health and Quality of Life Outcomes 2006 4:84
    Content type: Research Published on:

  6. The aims of the study were to assess the impact of both positive (PA) and negative affect (NA) on self-reported oral health-related quality of life and to determine the effect of including affectivity on the r...

    Authors: David S Brennan, Kiran A Singh, A John Spencer and Kaye F Roberts-Thomson
    Citation: Health and Quality of Life Outcomes 2006 4:83
    Content type: Research Published on:

  7. Screening asymptomatic individuals for neoplasia can have adverse consequences on quality of life. Colon cancer screening is widespread but the quality of life (QOL) consequences are unknown. This study determ...

    Authors: Doug Taupin, Sharon L Chambers, Mike Corbett and Bruce Shadbolt
    Citation: Health and Quality of Life Outcomes 2006 4:82
    Content type: Research Published on:

  8. In Canada, the incidence of Fetal Alcohol Spectrum Disorder (FASD) has been estimated to be 1 in 100 live births. Caused by prenatal exposure to alcohol, FASD is the leading cause of neuro-developmental disabi...

    Authors: Brenda C Stade, Bonnie Stevens, Wendy J Ungar, Joseph Beyene and Gideon Koren
    Citation: Health and Quality of Life Outcomes 2006 4:81
    Content type: Research Published on:

  9. Patient-reported measures can be used to examine whether drug differences other than clinical efficacy have an impact on outcomes that may be important to patients. Although exenatide and insulin glargine appe...

    Authors: Kristina Secnik Boye, Louis S Matza, Alan Oglesby, Karen Malley, Sunny Kim, Risa P Hayes and Robert Brodows
    Citation: Health and Quality of Life Outcomes 2006 4:80
    Content type: Research Published on:

  12. The SF-36 has been used in a number of previous studies that have investigated the health status of childhood cancer survivors, but it never has been evaluated regarding data quality, scaling assumptions, and ...

    Authors: Raoul C Reulen, Maurice P Zeegers, Crispin Jenkinson, Emma R Lancashire, David L Winter, Meriel E Jenney and Mike M Hawkins
    Citation: Health and Quality of Life Outcomes 2006 4:77
    Content type: Research Published on:

  13. Investigations of the structure of psychological well-being items are useful for advancing knowledge of what dimensions define psychological well-being in practice. Ryff has proposed a multidimensional model o...

    Authors: Rosemary A Abbott, George B Ploubidis, Felicia A Huppert, Diana Kuh, Michael EJ Wadsworth and Tim J Croudace
    Citation: Health and Quality of Life Outcomes 2006 4:76
    Content type: Research Published on:

  14. The PedsQL™ Present Functioning Visual Analogue Scales (PedsQL™ VAS) were designed as an ecological momentary assessment (EMA) instrument to rapidly measure present or at-the-moment functioning in children and...

    Authors: Sandra A Sherman, Sarajane Eisen, Tasha M Burwinkle and James W Varni
    Citation: Health and Quality of Life Outcomes 2006 4:75
    Content type: Research Published on:

  15. If decisions on health care spending are to be as rational and objective as possible, knowledge on cost-effectiveness of routine care is essential. Our aim, therefore, was to evaluate the cost-utility of routi...

    Authors: Pirjo Räsänen, Kari Krootila, Harri Sintonen, Tiina Leivo, Anna-Maija Koivisto, Olli-Pekka Ryynänen, Marja Blom and Risto P Roine
    Citation: Health and Quality of Life Outcomes 2006 4:74
    Content type: Research Published on:

  16. To assess the literature for the impact of iron overload and infusion Iron Chelation Therapy (ICT) on patients' quality of life (QoL), and the availability of QoL instruments for patients undergoing infusion I...

    Authors: Linda Abetz, Jean-Francois Baladi, Paula Jones and Diana Rofail
    Citation: Health and Quality of Life Outcomes 2006 4:73
    Content type: Research Published on:

  17. The influence of gender on the expression of COPD has received limited attention. Quality of Life (QoL) has become an important outcome in COPD patients. The aim of our study was to explore factors contributin...

    Authors: Juan P de Torres, Ciro Casanova, Concepción Hernández, Juan Abreu, Angela Montejo de Garcini, Armando Aguirre-Jaime and Bartolome R Celli
    Citation: Health and Quality of Life Outcomes 2006 4:72
    Content type: Research Published on:

  18. Patient-reported outcome (PROs) measures are being used more frequently in investigational studies of treatments for moderate to severe plaque psoriasis. The objective of this study was to examine the relation...

    Authors: Richard Shikiar, Mary Kaye Willian, Martin M Okun, Christine S Thompson and Dennis A Revicki
    Citation: Health and Quality of Life Outcomes 2006 4:71
    Content type: Research Published on:

  19. Patient reported outcomes provide the patient's perspective on the effectiveness of treatment. The draft Food and Drug Administration guidance on patient reported outcomes for labeling and promotional claims r...

    Authors: Dennis A Revicki, David Cella, Ron D Hays, Jeff A Sloan, William R Lenderking and Neil K Aaronson
    Citation: Health and Quality of Life Outcomes 2006 4:70
    Content type: Commentary Published on:

  20. The evaluation and use of patient reported outcome (PRO) measures requires detailed understanding of the meaning of the outcome of interest. The Food and Drug Administration (FDA) recently presented its draft ...

    Authors: Jan L Brożek, Gordon H Guyatt and Holger J Schünemann
    Citation: Health and Quality of Life Outcomes 2006 4:69
    Content type: Commentary Published on:

  21. Our objective was to test a brief, symptom index for advanced renal cell carcinoma, a disease affecting over 38,000 Americans each year and often diagnosed in late stages.

    Authors: David T Eton, David Cella, Jennifer Bacik and Robert J Motzer
    Citation: Health and Quality of Life Outcomes 2006 4:68
    Content type: Research Published on:

  22. The purpose of this review was to: (1) locate all exercise treatment studies of fibromyalgia (FM) patients from 1988 through 2005, (2) present in tabular format the key details of each study and (3) to provide...

    Authors: Kim Dupree Jones, Dianne Adams, Kerri Winters-Stone and Carol S Burckhardt
    Citation: Health and Quality of Life Outcomes 2006 4:67
    Content type: Review Published on:

  23. Measuring health-related quality of life (HRQOL) is important in arthritis and the SF-36v2 is the current state-of-the-art. It is only emerging how well the Centers for Disease Control and Prevention (CDC) HRQ...

    Authors: Thelma Mielenz, Elizabeth Jackson, Shannon Currey, Robert DeVellis and Leigh F Callahan
    Citation: Health and Quality of Life Outcomes 2006 4:66
    Content type: Research Published on:

  24. A recently published article by the Scientific Advisory Committee of the Medical Outcomes Trust presents guidelines for selecting and evaluating health status and health-related quality of life measures used i...

    Authors: Mark J Atkinson and Richard D Lennox
    Citation: Health and Quality of Life Outcomes 2006 4:65
    Content type: Commentary Published on:

  25. This proof of concept (POC) study was designed to evaluate the use of an Internet-based bulletin board technology to aid parallel cross-cultural development of thematic content for a new set of patient-reporte...

    Authors: Mark J Atkinson, Jan Lohs, Ilka Kuhagen, Julie Kaufman and Shamsu Bhaidani
    Citation: Health and Quality of Life Outcomes 2006 4:64
    Content type: Research Published on:

  26. Most studies on health-related quality of life (HRQOL) in children with cancer focussed on survivors. Only few studies have evaluated patients during ongoing oncological treatment. The aim of this study was a ...

    Authors: Markus A Landolt, Margarete Vollrath, Felix K Niggli, Hanspeter E Gnehm and Felix H Sennhauser
    Citation: Health and Quality of Life Outcomes 2006 4:63
    Content type: Research Published on:

  27. This article deals with the problem of interpreting health-related quality of life (HRQL) outcomes in clinical trials. First, we will briefly describe how dichotomization and item response theory can facilitat...

    Authors: Holger J Schünemann, Elie A Akl and Gordon H Guyatt
    Citation: Health and Quality of Life Outcomes 2006 4:62
    Content type: Commentary Published on:

  28. Health-Related Quality of Life (HRQOL) studies concerning children and adolescents are a growing field of research. The Pediatric Quality of Life Inventory (PedsQL™) is considered as a promising HRQOL instrume...

    Authors: Trude Reinfjell, Trond H Diseth, Marijke Veenstra and Arne Vikan
    Citation: Health and Quality of Life Outcomes 2006 4:61
    Content type: Research Published on:

  29. We evaluated how well physicians' global estimates of disease severity correspond to more specific physician-rated disease variables as well as patients' self-rated health and other patient variables.

    Authors: Kurt Kroenke, Kathleen W Wyrwich, William M Tierney, Ajit N Babu and Fredric D Wolinsky
    Citation: Health and Quality of Life Outcomes 2006 4:60
    Content type: Research Published on:

  30. The Multicenter Study of Hydroxyurea (HU) in Sickle Cell Anemia (MSH) previously showed that daily oral HU reduces painful sickle cell (SS) crises by 50% in patients with moderate to severe disease. The morbid...

    Authors: Samir K Ballas, Franca B Barton, Myron A Waclawiw, Paul Swerdlow, James R Eckman, Charles H Pegelow, Mabel Koshy, Bruce A Barton and Duane R Bonds
    Citation: Health and Quality of Life Outcomes 2006 4:59
    Content type: Research Published on:

  31. In situations where children are unable or unwilling to respond for themselves, measurement of quality of life (QOL) is often obtained by parent proxy-report. However the relationship between child self and pa...

    Authors: Joanne Cremeens, Christine Eiser and Mark Blades
    Citation: Health and Quality of Life Outcomes 2006 4:58
    Content type: Research Published on:

  32. Single item questions about self ratings of overall health status are widely used in both military and civilian surveys. Limited information is available to date that examines what relationships exist between ...

    Authors: Christopher K Haddock, Walker SC Poston, Sara A Pyle, Robert C Klesges, Mark W Vander Weg, Alan Peterson and Margaret Debon
    Citation: Health and Quality of Life Outcomes 2006 4:57
    Content type: Research Published on:

  33. The objective was to study whether a Kiswahili version of the OIDP (Oral Impacts on Daily Performance) inventory was valid and reliable for use in a population of older adults in urban and rural areas of Tanza...

    Authors: IA Kida, AN Åstrøm, GV Strand, JR Masalu and G Tsakos
    Citation: Health and Quality of Life Outcomes 2006 4:56
    Content type: Research Published on:

  34. To analyse the cross-diagnostic validity of the Functional Independence Measure (FIM™) motor items in patients with spinal cord injury, stroke and traumatic brain injury and the comparability of summed scores ...

    Authors: Å Lundgren-Nilsson, A Tennant, G Grimby and KS Sunnerhagen
    Citation: Health and Quality of Life Outcomes 2006 4:55
    Content type: Research Published on:

  35. Changes in scores on health status questionnaires are difficult to interpret. Several methods to determine minimally important changes (MICs) have been proposed which can broadly be divided in distribution-bas...

    Authors: Henrica C de Vet, Caroline B Terwee, Raymond W Ostelo, Heleen Beckerman, Dirk L Knol and Lex M Bouter
    Citation: Health and Quality of Life Outcomes 2006 4:54
    Content type: Commentary Published on:

  36. If the SF-36 summary scores are used as health status measures for the purpose of measuring health inequality it is relevant to be informed about the sources of the inequality in order to be able to target the...

    Authors: Jens Gundgaard and Jørgen Lauridsen
    Citation: Health and Quality of Life Outcomes 2006 4:53
    Content type: Research Published on:

  37. We constructed a concise multidimensional care burden scale that reflects circumstances unique to Japan, with a focus on intractable neurological diseases. We surveyed 646 family caregivers of patients with in...

    Authors: Mitsunori Miyashita, Aki Yamaguchi, Mami Kayama, Yugo Narita, Norikazu Kawada, Miki Akiyama, Akiko Hagiwara, Yoshimi Suzukamo and Shunichi Fukuhara
    Citation: Health and Quality of Life Outcomes 2006 4:52
    Content type: Research Published on:

  38. The Asthma Symptom Utility Index (ASUI) is a preference-based outcome measure used in US clinical trials and cost-effectiveness studies for asthma. This study evaluated ASUI preference weights in Europe to det...

    Authors: Emuella M Flood, Erwin De Cock, Ann-Christin Mörk and Dennis A Revicki
    Citation: Health and Quality of Life Outcomes 2006 4:51
    Content type: Research Published on:

  39. This research was conducted to confirm the validity and reliability and to assess the responsiveness and clinical meaningfulness of the OnyCOE-t™, a questionnaire specifically designed to measure patient-reported...

    Authors: Lori P Potter, Susan D Mathias, Monika Raut, Farid Kianifard and Amir Tavakkol
    Citation: Health and Quality of Life Outcomes 2006 4:50
    Content type: Research Published on:

  40. Many studies have demonstrated that health related quality of life (HRQoL) improves, on average, after coronary artery bypass graft surgery (CABGS). However, this average improvement may not be realized for al...

    Authors: Michael R Le Grande, Peter C Elliott, Barbara M Murphy, Marian UC Worcester, Rosemary O Higgins, Christine S Ernest and Alan J Goble
    Citation: Health and Quality of Life Outcomes 2006 4:49
    Content type: Research Published on:

  41. About 20% of schoolchildren and adolescents in Sweden suffer from perceived food hypersensitivity (e.g. allergy or intolerance). Our knowledge of how child food hypersensitivity affects parents HRQL and what a...

    Authors: Birgitta Marklund, Staffan Ahlstedt and Gun Nordström
    Citation: Health and Quality of Life Outcomes 2006 4:48
    Content type: Research Published on:

  42. Information on health related quality of life (HR-QOL) can be integrated with other classical health status indicators and be used to assist policy makers in resource allocation decisions. For this reason inst...

    Authors: Elena Savoia, Maria Pia Fantini, Pier Paolo Pandolfi, Laura Dallolio and Natalina Collina
    Citation: Health and Quality of Life Outcomes 2006 4:47
    Content type: Research Published on:

  43. Patient-reported quality of life is strongly affected by some dermatologic conditions. We developed a Japanese version of the Dermatology Life Quality Index (DLQI-J) and used psychometric methods to examine it...

    Authors: Natsuko Takahashi, Yoshimi Suzukamo, Motonobu Nakamura, Yoshiki Miyachi, Joseph Green, Yukihiro Ohya, Andrew Y Finlay and Shunichi Fukuhara
    Citation: Health and Quality of Life Outcomes 2006 4:46
    Content type: Research Published on:

  44. The management of Barrett's esophagus (BE), particularly high grade dysplasia (HGD), is an area of much debate and controversy. Surgical esophagectomy, intensive endoscopic surveillance and mucosal ablative te...

    Authors: Chin Hur, Eve Wittenberg, Norman S Nishioka and G Scott Gazelle
    Citation: Health and Quality of Life Outcomes 2006 4:45
    Content type: Research Published on:

  45. Cultural norms indicate that obesity reflects increased wealth and prosperity. Yet obesity is linked to serious medical illnesses. The purpose of this study was to determine if Ghanaian women would change thei...

    Authors: Rosemary B Duda, Naana Afua Jumah, Allan G Hill, Joseph Seffah and Richard Biritwum
    Citation: Health and Quality of Life Outcomes 2006 4:44
    Content type: Research Published on:

  46. Despite a growing literature on the efficacy of behavioral weight loss interventions, we still know relatively little about the long terms effects they have on HRQL. Therefore, we conducted a study to investig...

    Authors: Bryan Blissmer, Deborah Riebe, Gabriela Dye, Laurie Ruggiero, Geoffrey Greene and Marjorie Caldwell
    Citation: Health and Quality of Life Outcomes 2006 4:43
    Content type: Research Published on:

  47. The Osteoporosis Patient Satisfaction Questionnaire (OPSAT-Q) is a new measure of patient satisfaction with bisphosphonate treatment for osteoporosis. The objective of this study was to evaluate the psychometr...

    Authors: Emuella M Flood, Kathleen M Beusterien, Hannah Green, Richard Shikiar, Robert W Baran, Mayur M Amonkar and David Cella
    Citation: Health and Quality of Life Outcomes 2006 4:42
    Content type: Research Published on:

  48. Telesurveillance is a technologically based modality that allows the surveillance of patients in the natural setting, mainly home. It is based on communication technologies to relay information between a patie...

    Authors: Claude Vincent, Daniel Reinharz, Isabelle Deaudelin, Mathieu Garceau and Lise R Talbot
    Citation: Health and Quality of Life Outcomes 2006 4:41
    Content type: Research Published on:

  50. Health Related Quality of Life (HRQoL) studies on children with chronic illness such as thalassaemia are limited. We conducted the first study to investigate if children with thalassaemia have a lower quality ...

    Authors: Adriana Ismail, Michael J Campbell, Hishamshah Mohd Ibrahim and Georgina L Jones
    Citation: Health and Quality of Life Outcomes 2006 4:39
    Content type: Research Published on:
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Health and Quality of Life Outcomes

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