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  1. Sleep disruption is a prevalent symptom reported by survivors of childhood cancer. However, there is no validated instrument for assessing this symptom in this population group. To bridge the literature gap, t...

    Authors: K. Y. Ho, Katherine K. W. Lam, W. Xia, J. O. K. Chung, Ankie T. Cheung, Laurie L. K. Ho, S. Y. Chiu, Godfrey C. F. Chan and William H. C. Li
    Citation: Health and Quality of Life Outcomes 2021 19:176
    Content type: Research Published on:

  2. Although telemedical applications are increasingly used in the area of both mental and physical illness, there is no quality of life (QoL) instrument that takes into account the specific context of the healthc...

    Authors: Klara Greffin, Silke Schmidt, Neeltje van den Berg, Wolfgang Hoffmann, Oliver Ritter, Michael Oeff, Georg Schomerus and Holger Muehlan
    Citation: Health and Quality of Life Outcomes 2021 19:175
    Content type: Research Published on:

  3. The main aim of post-mastectomy breast reconstruction is to improve the patient’s quality of life, which makes high-quality and validated patient-reported outcome measurements essential. None of the establishe...

    Authors: Lynne Kamya, Emma Hansson, Linn Weick and Emma Hansson
    Citation: Health and Quality of Life Outcomes 2021 19:174
    Content type: Research Published on:

  4. The development of the minimum clinical important difference (MCID) can make it easier for researchers or doctors to judge the significance of research results and the effect of intervention measures, and impr...

    Authors: Dandan Ren, Ting Wu, Chonghua Wan, Gaofeng Li, Yanbo Qi, Yujing Fang and Jiudi Zhong
    Citation: Health and Quality of Life Outcomes 2021 19:173
    Content type: Research Published on:

  5. Neurodegenerative diseases (NDs) are one of the main causes of disability and dependence that have a great impact both on the quality of life of people with disabilities and their families. A majority of peopl...

    Authors: Marta Badia, M. Begoña Orgaz, Isabel Vicario-Molina, Eva González-Ortega, María Gómez-Vela, Alba Aza and M. Antonia Martín-Delgado
    Citation: Health and Quality of Life Outcomes 2021 19:172
    Content type: Research Published on:

  6. Idiopathic central precocious puberty (ICPP) reduces patient health-related quality of life (HRQoL). The impacts of disease and treatment on families are also an important concern. This study aimed to assess t...

    Authors: Hong Yang, Shunqing Luo, Xiaohua Liang, Qin Lin, Ting Cheng, Li Zeng, Fang Tang and Di Wu
    Citation: Health and Quality of Life Outcomes 2021 19:171
    Content type: Research Published on:

  7. Day care service (DCS) provides various activities in a professional environment to meet the old people with functional limitations. However, relatively little is known about the effects of DCS on physical and...

    Authors: Cheng-Fu Lin, Jia-Jyun Wu, Yu-Hui Huang, Li-Ying Ju, Shih-Yi Lin, Ying-Chyi Chou and Chu-Sheng Lin
    Citation: Health and Quality of Life Outcomes 2021 19:170
    Content type: Research Published on:

  8. Exercise adherence is important for achieving a long-term effect from musculoskeletal management. The Exercise Adherence Rating Scale (EARS), which was developed in 2017 as a patient reported outcome measure t...

    Authors: Hiroshi Takasaki, Shota Kawazoe, Takahiro Miki, Hiroki Chiba and Emma Godfrey
    Citation: Health and Quality of Life Outcomes 2021 19:169
    Content type: Research Published on:

  9. According to the World Health Organization (WHO), hearing loss (HL) affects up to 15% of the world’s adult population. Coping and personality are hypothesized to underlie quality of life (QoL) and distress sco...

    Authors: Øyvind Nordvik, Peder O. Laugen Heggdal, K. Jonas Brännström, Anne Kari Aarstad and Hans Jørgen Aarstad
    Citation: Health and Quality of Life Outcomes 2021 19:168
    Content type: Research Published on:

  10. Social deprivation has been shown to affect access to health care services, and influences outcomes for a variety of physical and psychological conditions. However, the impact on patient satisfaction remains l...

    Authors: Andrew R. Stephens, Jared W. Potter, Andrew R. Tyser and Nikolas H. Kazmers
    Citation: Health and Quality of Life Outcomes 2021 19:167
    Content type: Research Published on:

  11. The aim of this study was to provide a path model for assessing the direct and/or indirect effects of psychological/behavioral parameters on health-related quality of life among women with vaginismus.

    Authors: Atefeh Velayati, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei and Anoshirvan Kazemnejad
    Citation: Health and Quality of Life Outcomes 2021 19:166
    Content type: Research Published on:

  12. Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact are the four oral health-related quality of life (OHRQoL) dimensions (4D) or areas in which oral disorders impact pediatric patients...

    Authors: Katrin Bekes, Mike T. John, Ksenija Rener-Sitar, Mohammad H. Al-Harthy, Ambra Michelotti, Daniel R. Reissmann, Julijana Nikolovska, Sahityaveera Sanivarapu, Folake B. Lawal, Thomas List, Sanja Peršić Kiršić, Ljiljana Strajnić, Rodrigo Casassus, Kazuyoshi Baba, Martin Schimmel, Ama Amuasi…
    Citation: Health and Quality of Life Outcomes 2021 19:165
    Content type: Research Published on:

  13. There has been limited success in achieving integration of patient-reported outcomes (PROs) in clinical trials. We describe how stakeholders envision a solution to this challenge.

    Authors: Theresa M. Coles, Adrian F. Hernandez, Bryce B. Reeve, Karon Cook, Michael C. Edwards, Marc Boutin, Elizabeth Bush, Arnold Degboe, Lothar Roessig, Amy Rudolph, Pauline McNulty, Nikunj Patel, Trish Kay-Mugford, Margaret Vernon, Michael Woloschak, Gustavo Buchele…
    Citation: Health and Quality of Life Outcomes 2021 19:164
    Content type: Commentary Published on:

  14. An automated web-based assessment and monitoring system (www.​psynary.​com) has been developed to assist non-specialist clinicians in managing common mood and ...

    Authors: Yuki Takao, Eduardo Figueroa, Kevin Fernand Jean Berna, Youjin Jo, Lee Andrew Kissane, Kimio Yoshimura, Richard Tranter and Richard J Porter
    Citation: Health and Quality of Life Outcomes 2021 19:163
    Content type: Research Published on:

  15. The EQ-5D-3L is a widely used generic health-related quality of life measure commonly applied to describe health outcomes and to measure disease burden. The aim of this study was to generate Brazilian populati...

    Authors: Marisa Santos, Andrea L. Monteiro and Bráulio Santos
    Citation: Health and Quality of Life Outcomes 2021 19:162
    Content type: Research Published on:

  16. This letter was written to address two concerns about the results of the paper published by Zeynep et al. (BMC Health Qual Life Outcomes 18:265, 2020). First, the differences between the two groups in the envi...

    Authors: Kazuoki Inoue, Jun Watanabe and Eiichi Kakehi
    Citation: Health and Quality of Life Outcomes 2021 19:161
    Content type: Letter to the Editor Published on:

    The Letter to this article has been published in Health and Quality of Life Outcomes 2021 19:203

  17. An increased prevalence of adolescent metabolic syndrome (MS) is associated with adulthood cardiovascular diseases. This study aimed to explore the potential relationship of quality of life (QoL) and personali...

    Authors: Xiaohua Liang, Peng Zhang, Shunqing Luo, Guifang Zhang, Xian Tang and Lingjuan Liu
    Citation: Health and Quality of Life Outcomes 2021 19:160
    Content type: Research Published on:

  18. The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was developed to accurately assess the pain, urinary symptoms, and quality of life related to chronic prostatitis/chronic pelvic p...

    Authors: Rong-liang Dun, Jennifer Tsai, Xiao-hua Hu, Jian-min Mao, Wen-jing Zhu, Guang-chong Qi and Yu Peng
    Citation: Health and Quality of Life Outcomes 2021 19:159
    Content type: Review Published on:

  19. Patient reported outcome measures (PROMs) are used to understand the impact of lower limb reconstruction surgery on patients’ quality of life (QOL). Existing measures have not been developed to specifically ca...

    Authors: H. Leggett, A. Scantlebury, A. Byrne, M. Harden, C. Hewitt, G. O’Carroll, H. Sharma and C. McDaid
    Citation: Health and Quality of Life Outcomes 2021 19:158
    Content type: Review Published on:

  20. The 12-item Short-Form Health Survey version 2 (SF-12v2), a widely used, generic patient-reported measure of health status that provides summary scores of physical and mental health. No study to date has exami...

    Authors: Sze-Ee Soh, Renata Morello, Darshini Ayton, Susannah Ahern, Ri Scarborough, Claire Zammit, Margaret Brand, Robert G. Stirling and John Zalcberg
    Citation: Health and Quality of Life Outcomes 2021 19:157
    Content type: Research Published on:

  21. As China’s aging trend intensifies and the proportion of empty nests increases, the health-related quality of life of the elderly is the focus of social attention. Previous studies focused on the quality of li...

    Authors: Chichen Zhang, Yuan Cai, Yaqing Xue, Xiao Zheng, Xiaozhao Yang, Jiao Lu, Lihong Hou and Mimi Li
    Citation: Health and Quality of Life Outcomes 2021 19:156
    Content type: Research Published on:

  22. The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respect...

    Authors: A. M. Garratt, H. Furunes, C. Hellum, T. Solberg, J. I. Brox, K. Storheim and L. G. Johnsen
    Citation: Health and Quality of Life Outcomes 2021 19:155
    Content type: Research Published on:

  23. We conducted a real-life study of health-related quality of life (HRQoL) transformation before and 12 weeks after sofosbuvir and daclatasvir therapy in HCV/HIV co-infected patients. Factors related to the sign...

    Authors: Evy Yunihastuti, Fhadilla Amelia, Arini Ika Hapsari, Bramantya Wicaksana, Veritea Natali, Alvina Widhani, Andri Sanityoso Sulaiman and Teguh Harjono Karjadi
    Citation: Health and Quality of Life Outcomes 2021 19:154
    Content type: Research Published on:

  24. The Wisconsin Upper Respiratory Symptom Survey for Kids (WURSS-K) is a self-administered questionnaire developed to evaluate the severity of the common cold. It is a patient-oriented instrument that evaluates ...

    Authors: Katarzyna Ostrzyżek-Przeździecka, Mariusz Panczyk, Aleksandra Ratajczak, Michał Bronikowski and Wojciech Feleszko
    Citation: Health and Quality of Life Outcomes 2021 19:153
    Content type: Research Published on:

  25. With the increase of the number of smokers, tobacco exposure among pregnant women is becoming more and more common. Pregnant women exposed to first-hand smoke and second-hand smoke are susceptible to physiolog...

    Authors: Weiwei Sun, Xinyu Huang, Huailiang Wu, Casper J. P. Zhang, Zongzhi Yin, Qianqian Fan, Huiyun Wang, Pallavi Jayavanth, Babatunde Akinwunmi, Yanxin Wu, Zilian Wang and Wai-kit Ming
    Citation: Health and Quality of Life Outcomes 2021 19:152
    Content type: Research Published on:

  26. This study aims to explore the incidence of hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and the influence of hypoglycemia on the specific quality of life in T2DM patients.

    Authors: Chao Wu, Yi-Ling Ge, Xin-Yan Zhang, Ming-Chao Liu, Chun-Ni Heng, Lin-Yuan Zhang, Yan-Ling Du, Shi-Zhe He, Lei Shang and Hong-Juan Lang
    Citation: Health and Quality of Life Outcomes 2021 19:151
    Content type: Research Published on:

  27. Degenerative cervical myelopathy (DCM) can significantly impair a patient’s quality of life (QOL). In this study, we aimed to identify predictors associated with QOL improvement after surgery for DCM.

    Authors: Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takuya Miyamoto, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga…
    Citation: Health and Quality of Life Outcomes 2021 19:150
    Content type: Research Published on:

  28. The diagnosis of breast cancer and the subsequent treatment undermine patients’ participation in social activities. This study aimed to carry out a cross-cultural adaption and analysis of the construct validit...

    Authors: Tingting Cai, Qingmei Huang, Fulei Wu and Changrong Yuan
    Citation: Health and Quality of Life Outcomes 2021 19:149
    Content type: Research Published on:

  29. Previous studies of patients with liver cirrhosis have not considered the broad range of symptoms or the association between healthy behavior and quality of life. The purposes of this study were to examine the...

    Authors: Myung Kyung Lee and Woo Jin Chung
    Citation: Health and Quality of Life Outcomes 2021 19:148
    Content type: Research Published on:

  30. The assessment of patient satisfaction during treatment is essential to provide patient-centered high-quality cancer care. Nevertheless, no German instrument assesses patient satisfaction with comprehensive ca...

    Authors: Peter Esser, Leon Sautier, Susanne Sarkar, Georgia Schilling, Carsten Bokemeyer, Uwe Koch, Michael Friedrich, Gautier Defossez and Anja Mehnert-Theuerkauf
    Citation: Health and Quality of Life Outcomes 2021 19:147
    Content type: Research Published on:

  31. The goal of this article was to research the psychometric properties of the WHOQOL-BREF(PT) instrument in a sample of elderly citizens residing in a rural area in their own homes or at family members’ or frien...

    Authors: Margarida Goes, Manuel Lopes, João Marôco, Henrique Oliveira and César Fonseca
    Citation: Health and Quality of Life Outcomes 2021 19:146
    Content type: Research Published on:

  32. Existing studies on health-related quality of life (HRQoL) mainly covered single growth stages of childhood or adolescence and did not report on the trends in the relationships of HRQoL with sleep duration, ph...

    Authors: Carlos K. H. Wong, Rosa S. Wong, Jason P. Y. Cheung, Keith T. S. Tung, Jason C. S. Yam, Michael Rich, King-Wa Fu, Prudence W. H. Cheung, Nan Luo, Chi Ho Au, Ada Zhang, Wilfred H. S. Wong, Jiang Fan, Cindy L. K. Lam and Patrick Ip
    Citation: Health and Quality of Life Outcomes 2021 19:145
    Content type: Research Published on:

  33. Most of the studies reporting the negative impact of idiopathic nephrotic syndrome on health-related quality of life in children and adolescents were conducted with generic quality-of-life instruments rather t...

    Authors: Ann E. Aronu, Samuel N. Uwaezuoke and Uzoamaka V. Muoneke
    Citation: Health and Quality of Life Outcomes 2021 19:144
    Content type: Review Published on:

  34. Hypersensitivity reactions to drugs are unpredictable and can be very complex and severe, even life threatening. Assess its impact on patient’s health related quality of life (HRQoL) is crucial. The Drug Hyper...

    Authors: E. Dias de Castro, J. Barbosa, A. M. Mesquita, A. Caires, L. Ribeiro, J. R. Cernadas and I. Baiardini
    Citation: Health and Quality of Life Outcomes 2021 19:143
    Content type: Research Published on:

  35. Heart failure (HF) is a major and growing medical and economic problem, with high prevalence and incidence rates worldwide. Cardiac Biomarker is emerging as a novel tool for improving management of patients wi...

    Authors: Antonio Leon-Justel, Jose I. Morgado Garcia-Polavieja, Ana Isabel Alvarez-Rios, Francisco Jose Caro Fernandez, Pedro Agustin Pajaro Merino, Elena Galvez Rios, Ignacio Vazquez-Rico and Jose Francisco Diaz Fernandez
    Citation: Health and Quality of Life Outcomes 2021 19:142
    Content type: Research Published on:

  36. Many studies have been conducted in Iran on the postpartum quality of life, and the majority have used the general quality of life questionnaire. With a specific tool in this context, the dimensions of materna...

    Authors: Tahereh Mokhtaryan-Gilani, Giti Ozgoli, Nourossadat Kariman, Hamid Sharif Nia, Mahbobeh Ahmadi Doulabi and Malihe Nasiri
    Citation: Health and Quality of Life Outcomes 2021 19:141
    Content type: Research Published on:

  37. Health Related Quality of Life (HRQL) is a multi-dimensional construct that can comprehensively evaluate the patient’s health status, including physical, emotional, mental and social well-being. In this study,...

    Authors: Rui Huang, Jian-Gao Fan, Jun-Ping Shi, Yi-Min Mao, Bing-Yuan Wang, Jing-Min Zhao, Lun-Gen Lu, Bi-Hui Zhong, Zheng-Sheng Zou, You-Qing Xu, Yi-Nong Ye, Long-Gen Liu, Lian-Jie Lin, Jian-Ping Li, Hui-Ying Rao and Lai Wei
    Citation: Health and Quality of Life Outcomes 2021 19:140
    Content type: Research Published on:

  38. To develop a priority-based patient/parent reported outcome measure for children with lower-limb differences (LD) by adapting the Gait Outcomes Assessment List (GOAL) questionnaire.

    Authors: Jennifer A. Dermott, F. Virginia Wright, Nancy M. Salbach and Unni G. Narayanan
    Citation: Health and Quality of Life Outcomes 2021 19:139
    Content type: Research Published on:

  40. The translated and culturally adapted German version of the Veterans Rand 36 Items Health Survey (VR-36), and its short form, the VR-12 counterpart, were validated in a German sample of orthopedic (n = 399) an...

    Authors: Ines Buchholz, You-Shan Feng, Maresa Buchholz, Lewis E. Kazis and Thomas Kohlmann
    Citation: Health and Quality of Life Outcomes 2021 19:137
    Content type: Research Published on:

  41. Patients’ psychological health may influence recovery and functional outcomes after total knee arthroplasty (TKA). Pain catastrophizing, known to be associated with poor function following TKA, encompasses rum...

    Authors: Vesta C. Nwankwo, William A. Jiranek, Cynthia L. Green, Kelli D. Allen, Steven Z. George and Janet Prvu Bettger
    Citation: Health and Quality of Life Outcomes 2021 19:136
    Content type: Research Published on:

  42. Fatigue negatively influences health-related quality of life. It is questionable whether fatigue is sufficiently covered by the EQ-5D. This study investigated whether fatigue is covered by the existing domains...

    Authors: I. Spronk, S. Polinder, G. J. Bonsel, M. F. Janssen and J. A. Haagsma
    Citation: Health and Quality of Life Outcomes 2021 19:135
    Content type: Research Published on:

  43. The Client Satisfaction with Devices (CSD) module of the Orthotics and Prosthetics Users’ Survey is an extensively used questionnaire that measures patients’ satisfaction with orthosis and prosthesis. However,...

    Authors: Hadeel R. Bakhsh, Nilüfer Kablan, Walaa Alammar, Yaşar Tatar and Giorgio Ferriero
    Citation: Health and Quality of Life Outcomes 2021 19:134
    Content type: Research Published on:

  44. The use of Patient Reported Outcome Measures (PROMS) in clinical practice has the potential to promote patient-centred care and improve patients’ quality of life. Individualized PROMs may be particularly helpf...

    Authors: Ian Porter, Antoinette Davey, Jaheeda Gangannagaripalli, Jonathan Evans, Charlotte Bramwell, Philip Evans, Chris Gibbons and Jose M. Valderas
    Citation: Health and Quality of Life Outcomes 2021 19:133
    Content type: Research Published on:

  45. Standardized coding of the content presented in patient reported outcome measures can be achieved using classification frameworks, and the resulting data can be used for ascertaining content validity or compar...

    Authors: Derek Rosa, Joy MacDermid and Dorota Klubowicz
    Citation: Health and Quality of Life Outcomes 2021 19:132
    Content type: Research Published on:

  46. Self-reported measures play a crucial role in research, clinical practice and health assessment. Instruments used to assess self-reported health-related quality of life (HRQoL) need validation to ensure that t...

    Authors: Allen Naamala, Lars E. Eriksson, Jackson Orem, Gorrette K. Nalwadda, Zarina Nahar Kabir and Lena Wettergren
    Citation: Health and Quality of Life Outcomes 2021 19:131
    Content type: Research Published on:

  48. Heart failure (HF) is a severe and self-limiting syndrome. Its signs and symptoms are believed to predict poorer health-related quality of life scores, which are mainly influenced by deterioration in physical ...

    Authors: Paula Cristina Silva, Omar Pereira de Almeida Neto and Elmiro Santos Resende
    Citation: Health and Quality of Life Outcomes 2021 19:129
    Content type: Research Published on:

  49. In health and social service evaluations, including research on homelessness, quality of Life (QOL) is often used as a key indicator of well-being among service users. However, no typology has been developed o...

    Authors: Gesthika Kaltsidis, Guy Grenier, Zhirong Cao, Nadia L’Espérance and Marie-Josée Fleury
    Citation: Health and Quality of Life Outcomes 2021 19:128
    Content type: Research Published on:

  50. No review to date has evaluated the association between physical fitness and health-related quality of life (HRQoL) in healthy children and adolescents. The aims of this systematic review and meta-analysis wer...

    Authors: Alberto Bermejo-Cantarero, Celia Álvarez-Bueno, Vicente Martínez-Vizcaino, Andrés Redondo-Tébar, Diana P. Pozuelo-Carrascosa and Mairena Sánchez-López
    Citation: Health and Quality of Life Outcomes 2021 19:127
    Content type: Review Published on:
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Health and Quality of Life Outcomes

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