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Table 3 Comparison of child-reported and parent-reported fatigue scores between patients and comparisons over time

From: Fatigue in children who have recently completed treatment for acute lymphoblastic leukemia: a longitudinal study

 

Group Main Effect

Group by Time interaction

Time 1

Time 2

Time 3

Child report

Mean differencea (95% CI)

Effect size

p

Χ2 (df)

p

Mean differencea (95% CI)

Effect size

p

Mean differencea (95% CI)

Effect size

p

Mean differencea (95% CI)

Effect size

p

Total fatigue

4.92 (-0.02, 9.86)

0.28

0.051

2.04 (2)

0.360

3.89 (-2.11, 9.90)

0.23

0.203

3.13 (-3.20, 9.46)

0.18

0.332

7.70 (1.30, 14.11)

0.45

0.018

General fatigue

5.34 (0.014, 10.53)

0.28

0.044

0.53 (2)

0.976

5.65 (-0.95, 12.25)

0.30

0.093

5.00 (-1.98, 11.99)

0.26

0.160

4.82 (-2.27, 11.90)

0.25

0.183

Sleep/rest fatigue

4.04 (-1.31, 9.39)

0.20

0.139

2.60 (2)

0.272

2.03 (-5.00, 9.07)

0.10

0.571

1.97 (-5.50, 9.44)

0.10

0.605

8.32 (0.74, 15.90)

0.41

0.031

Cognitive fatigue

5.78 (-0.81, 12.37)

0.24

0.086

2.33 (2)

0.311

4.26 (-4.02, 12.53)

0.18

0.313

3.10 (-5.66, 11.86)

0.13

0.488

10.21 (1.34, 19.08)

0.43

0.024

Parent report

Mean differencea (95% CI)

Effect size

p

Χ2 (df)

p

Mean differencea (95% CI)

Effect size

p

Mean differencea (95% CI)

Effect size

p

Mean differencea (95% CI)

Effect size

p

Total fatigue

12.10 (7.37, 16.82)

0.76

< 0.001

4.13 (2)

0.127

13.87 (8.63, 19.11)

0.87

< 0.001

9.47 (4.02, 14.91)

0.60

0.001

13.07 (7.57, 18.57)

0.82

< 0.001

General fatigue

13.41 (8.47, 18.34)

0.76

< 0.001

8.55 (2)

0.014

17.02 (11.26, 22.77)

0.97

< 0.001

8.56 (2.52, 14.60)

0.49

0.005

14.35 (8.23, 20.47)

0.82

< 0.001

Sleep/rest fatigue

9.49 (4.65, 14.33)

0.58

< 0.001

4.27 (2)

0.118

12.43 (6.85, 18.00)

0.76

< 0.001

6.80 (0.97, 12.64)

0.42

0.022

8.74 (2.83, 14.64)

0.53

0.004

Cognitive fatigue

13.22 (7.08, 19.36)

0.65

< 0.001

1.58 (2)

0.454

12.19 (5.37, 19.01)

0.60

< 0.001

12.87 (5.78, 20.00)

0.63

< 0.001

15.78 (8.62, 22.94)

0.78

< 0.001

  1. a Comparison group–patient group. Time 1 = 3-months post-treatment completion. Time 2 = 15-months post-treatment completion. Time 3 = 27-months post-treatment completion