Table 1 Summary of reviewed questionnaires
From: How quality of life is measured in studies of nutritional intervention: a systematic review
Questionnaire | Target population | Definition | Frequency of use | References |
|---|---|---|---|---|
SF-36 | General | 36-item self-report measure of HRQoL with physical health and mental health component scores derived from eight subscales measuring different domains of health-related quality of life: physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. [16] | 27 | [17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43] |
SF-12 | General | Shorter version of the SF-36. [44] | 3 | |
EQ-5D-3L | General | Self-reported measure of HRQoL using 3 levels to describe health across five dimensions (Mobility, Usual Activities, Self-care, Pain & Discomfort, and Anxiety & Depression). [48] | 15 | |
EQ-5D-5L | General | Self-reported measure of HRQoL using 5 levels to describe health across five dimensions (Mobility, Usual Activities, Self-care, Pain & Discomfort, and Anxiety & Depression) [48] | 11 | |
EQ-5D VAS | General | Self-rated health scale included in the EQ-5D questionnaire (both 3L and 5L version) that allows individuals to rate their current health status on a scale from 0 to 100. The VAS score is considered a global measure of health status [48] | 1 | [74] |
WHOQoL-BREF | General | 26-items HRQoL scale consisting of four domains (physical health, psychological, social, and environmental). Each domain is scored on a 5-point scale from 0 to 100, with higher scores indicating better QoL [75] | 6 | |
PedsQoL | General | Instrument for assessing patients and parents’ perceptions of HRQoL in pediatric patients with chronic health conditions. Consists of a 15-item core measure of global HRQoL AND eight supplemental modules assessing specific symptoms or treatment domains [82] | 2 | |
AQoL-8D | General | QoL questionnaire based in AQoL-6D questionnaire which adds explicit dimensions for self-worth and happiness and expands the items in mental health [85,86,87] | 2 | |
AQoL-6D | General | QoL questionnaire based in AQoL-4D questionnaire were. pain and coping dimensions are added and mental health and independent living items are increased from 3 to 4 items [86, 90] | 1 | [91] |
AQoL-4D | General | QoL questionnaire developed by Australian researchers, is a multi-attribute utility HRQoL instrument. While it can be used to measure HRQoL alone, its main purpose is to measure the ‘utility’ of health states. This version contains 4 dimensions (independent living, social relationships, physical senses and psychological wellbeing [86, 92]) | 1 | [93] |
NHP | General | Self-administered questionnaire that measures an individual's physical, emotional, and social well-being in the context of their current health status [94] | 1 | [95] |
POMS2 | General | Questionnaire used to evaluate transient feelings and mood in individuals aged 13 years and above. It has evolved from the original POMS and is applicable in multiple settings, such as monitoring mood changes during interventions and assessing the impact of physical disease on psychological functioning [96] | 1 | [97] |
PROMIS SF | General | Standardized set of measures developed by the National Institutes of Health (NIH) to assess various aspects of health-related quality of life (HRQoL) from the patient's perspective [98] | 1 | [99] |
SIP | General | Behaviorally based measure of health status used to assess a person's perception of their health status with respect to their disease impact [100] | 1 | [101] |
CANCER QOLQ | ||||
EORTC-QLQ-C30 | Cancer | HRQoL questionnaire for individuals with cancer incorporating five functional scales (physical, role, cognitive, emotional, and social), three symptom scales (fatigue, pain, and nausea and vomiting), and a global health and quality-of-life scale [102] | 27 | [19, 68, 103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127] |
EORTC-QLQ-OES18 | Cancer (esophageal symptoms) | EORTC questionnaire module used with the EORTC-QLQ-C30 to assess QoL in patients with esophageal cancer undergoing any single or combination of treatments including: esophagectomy, chemoradiation, endoscopic palliation or palliative chemotherapy and/or radiotherapy [128] | 4 | |
EORTC-QLQ-H&N35 | Cancer (Head and neck) | EORTC questionnaire module used with the EORTC-QLQ-C30 to assess QoL in patients with head and neck cancer undergoing any single or combination of treatments (i.e. surgery, radiotherapy and chemotherapy) [129] | 2 | |
EORTC-QLQ-BR23 | Cancer (Breast) | EORTC questionnaire module used with the EORTC-QLQ-C30 to assess QoL in patients with breast cancer undergoing any single or combination of treatments (i.e. surgery, chemotherapy, radiotherapy and endocrine treatment) [129] | 1 | [119] |
EORTC-QLQ-PAN26 | Pancreatic cancer | EORTC questionnaire module used with the EORTC-QLQ-C30 to assess QoL in patients with pancreatic cancer. Includes 26 items related to disease symptoms, treatment side-effects and emotional issues specific to pancreatic cancer [129] | 1 | [124] |
FACT-G | Cancer | Questionnaire designed to measure four domains of HRQOL in cancer patients: Physical, social, emotional, and functional well-being [130] | 2 | |
FACT-G7 | Cancer | The FACT-G7 (Functional Assessment of Cancer Therapy-General 7 item) is a shortened version of the FACT-G questionnaire [132] | 1 | [133] |
FAACT | Anorexia and Cachexia by Cancer | QoL questionnaire for both cancer and HIV-infected patients with anorexia/cachexia [134] | 1 | [135] |
FACT-B | Cancer (Breast) | Self-report instrument designed to measure QoL in patients with breast cancer. The FACT-B consists of the FACT-General (FACT-G) plus specific concerns related to breast cancer) [136] | 1 | [131] |
FACT-C | Cancer (colorectal) | Self-report instrument designed to measure QoL in patients with colorectal cancer. The FACT-C consists of the FACT-General (FACT-G) plus specific concerns related to colorectal cancer [137] | 1 | [46] |
OTHER DISEASE-SPECIFIC QOLQ | ||||
SGRQ | Obstructive airways disease | Self-administered HRQoL to measure three components: Symptoms, Activity, and Impacts. Scores ranging from 0 to 100 with higher scores indicating less QoL. It is valid for COPD, bronchiectasis, and asthmatic populations. [138] | 3 | |
MLHFQ | Heart failure | Self-administered questionnaire that measures the impact of heart failure on QoL using a 21 item six-point Likert scale. It provides a total score ranging from 0 to 105 with higher scores indicating worse quality of life. [142] | 2 | |
PAC-QoL | Constipation | Self-administered questionnaire used to assess the impact of constipation on a patient's QoL. It consists of 28 items across four domains(physical discomfort, psychosocial discomfort, worries and concerns, and satisfaction.) [145] | 2 | |
QUALIDEM | Dementia | Two-versions QoLQ to be used in different stages of dementia: 37-item version for people with mild to severe dementia covering nine domains of QoL (care relationship, positive affect, negative affect, restless tense behavior, positive self-image, social relations, social isolation, feeling at home, and having something to do) and the 18- items version for people with very severe dementia (deleting domains of positive self-image, feeling at home, and having something to do). [148] | 2 | |
CLDQ | Chronic liver disease | 29- items QoL questionnaire for assessing the HRQoL in individuals with chronic liver disease covering 8 domains (abdominal symptoms, fatigue, systemic symptoms, activity, emotional function, worry). [151] | 1 | [152] |
IWQOL-Lite | Weight | Shortened version of the Impact of Weight on QoL (IWQOL) questionnaire. It is a 31-item instrument consisting of five scales: Physical Function, Self-Esteem, Sexual Life,, Public Distress, and Work. [153] | 1 | [17] |
KDQOL-SF | Chronic kidney disease | Shorter version, self-report measure developed for individuals with kidney disease and those on dialysis. It includes kidney disease-targeted items, (effects of the disease of activities of daily living, work status, and social interaction) physical and mental health items) and 1 overall health rating item. [154] | 1 | [70] |
KOOS QoL | Knee Injury and Osteoarthritis | Extension of the WOMAC Osteoarthritis Index to evaluate subjects with knee injury and osteoarthritis. It contains 5 scored subscales: Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related (QOL). [155] | 1 | [156] |
MiniAQLQ | Asthma | MiniAQLQ is a shortened version of the AQLQ(S) questionnaire. It consists in 15 questions covering symptoms, activities, emotions, and environment domains. [157] | 1 | [158] |
MSQoL-54 | Multiple sclerosis | HRQoL measure that combines both generic (based in SF-36 questionnaire) and MS-specific items (such as fatigue, cognitive function, etc.) into a single instrument divided in physical function, role limitations-physical, role limitations-emotional, pain, emotional well-being, energy, health perceptions, social function, cognitive function, health distress, overall quality of life, and sexual function subscales. [159, 160] | 1 | [161] |
PDQ-39 | Parkinson | Tool that assesses how often people with Parkinson's experience difficulties across 8 dimensions of daily living including relationships, social situations, and communication. [162] | 1 | [163] |
QoL-B | Non-cystic fibrosis (CF) bronchiectasis | Self-administered measure assessing symptoms, functioning and HRQoL of patients with non-cystic fibrosis and bronchiectasis. It contains 37 items on 8 scales (Respiratory Symptoms, Physical, Role, Emotional and Social Functioning, Vitality, Health Perceptions and Treatment Burden). [164] | 1 | [165] |
QUALEFFO-41 | Vertebral deformities | Questionnaire for measuring QoL in patients with vertebral osteoporosis. It consists of questions and visual analogue scales in pain, activities of daily living, jobs around the house, mobility, leisure and social activities, general health perception and mood domains. [166] | 1 | [52] |
RV-DQOL | Diabetes | Questionnaire with three major domains: diabetes life satisfaction scale (QoL satisfy), disease impact scale (QoL impact), disease related worries scale (QoL worry) and a general health questionnaire (GHQ). This instrument has been used in numerous studies in both type I DM and type 2 DM patients. [167] | 1 | [168] |
SWAL-QOL | Dysphagia | SWAL-QOL, a disease-specific measure of quality of life and quality of care for patients with oropharyngeal dysphagia. It assesses 10 QoL concepts; eight of which are dysphagia-related QoL (food selection, burden, mental health, social functioning, fear, eating duration, eating desire, communication) and two pertaining to general QoL (sleep and fatigue). [169] | 1 | [78] |