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Table 3 Conditional likelihood ratio (CLR) fit statistics and cronbach’s alpha for the 16 multi-item domains of the Consequences of screening-lung cancer (COS-LC) questionnaire

From: Validation of the psychosocial consequences of screening in lung cancer questionnaire in the international lung screen trial Australian cohort

Scale (# of items)

CLR

df

P value

Local Response Dependency

Differential item functioning

Cronbach’s alpha

Consequences of Lung Cancer Screening Part 1

Anxiety (7)

34.29

18

0.0116*

2 & 3

Nil significant

0.824

Behaviour (7)

16.13

20

0.7085

4 &10, 4 & 20, 5 &17, 8 & 20

Nil significant

0.855

Dejection (6)

26.15

16

0.0520

Nil significant

Nil significant

0.873

Negative impact on sleep (4)

24.53

11

0.0107*

6 & 16, 6 & 24, 16 & 21

Item 21 & Work

0.849

Negative impact on sleep (-21) (3)

11.72

8

0.1640

16 & 24

Nil significant

0.854

Focus on symptoms (8)

62.97

22

< 0.0001*

26 & 37, 26 & 40, 26 & 45, 26 & 47, 42 & 47, 45 & 49

Item 40 & Education

0.739

Focus on symptoms (-40) (7)

62.38

19

< 0.0001*

26 & 37, 26 & 45, 26 & 49, 42 & 47, 45 & 49

Nil significant

0.747

Stigmatisation (4)

10.06

11

0.5253

Nil significant

Nil significant

0.873

Introvert (6)

26.30

17

0.0691

39 & 44

Nil significant

0.754

Harms of smoking (2)

12.34

5

0.0304

-

Item 25 & Smoking, Item 30 & Smoking

0.820

Self-Blame (5)

32.46

14

0.0034*

35 & 36, 35 & 38, 35 & 48, 35 & 50, 36 & 38, 36 & 48, 38 & 50, 48 & 50

Item 35 & Smoking

0.955

Self-blame (-35) (4)

5.25

11

0.9185

36 & 38, 36 & 48, 48 & 50

Nil significant

0.951

Consequences of Lung Cancer Screening Part 2

Lung cancer (2)

1.84

3

0.6059

-

Nil significant

0.671

Relaxed/Calm (3)

6.28

5

0.2796

Nil significant

Nil significant

0.731

Social relations (3)

1.14

3

0.7685

Nil significant

Nil significant

0.817

Existential values (6)

15.65

11

0.1547

11 & 12

Nil significant

0.853

Impulsivity (6)

1.91

11

0.9988

Nil significant

Nil significant

0.778

Empathy (3)

11.18

4

0.0247

18 & 20

Item 15 & Smoking, Item 18 & Smoking

0.698

Empathy (-15) (2)

0.00

2

0.9999

Nil significant

Nil significant

0.693

Empathy (-18) (2)

0.00

2

0.9994

Nil significant

Nil significant

0.540

Regretful about still smoking (6)

24.18

5

0.0002*

27 & 28

Nil significant

0.832

  1. *Benjamini-Hochberg rejects all p-values less than 0.0143 to control the false discovery rate at 0.05
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