Anchor | Groups | N | LS mean (SE) | 95% CI | p value |
|---|
PGI-S SD | Responders | 445 | – 7.27 (0.27) | – 7.80, − 6.74 | < 0.0001 |
Non-responders | 419 | – 0.65 (0.28) | – 1.20, − 0.11 |
PGI-C SD | Responders | 590 | – 6.33 (0.23) | – 6.78, − 5.89 | < 0.0001 |
Non-responders | 272 | 0.91 (0.33) | 0.25, 1.57 |
- p value: analysis of covariance with alpha = 0.05 level comparing “responders” and “non-responders”. PGI-S SD: “responders” = ≥ 1-point decrease from baseline to week 12, “non-responders” = all others. PGI-C SD: “responders” = any improvement at week 12, “non-responders” = all others
- CI Confidence interval, LS Least squares, PGI-C SD Patient Global Impression of Change Sleep Disturbance, PGI-S SD Patient Global Impression of Severity Sleep Disturbance, SE Standard error
