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Table 4 Coefficients (95% C.I.) of linear regression analysis between EQ-VAS and EQ-5D and PROMIS adjusted by demographics

From: Measurement properties of the EQ-5D-5L and PROPr in patients with spinal muscular atrophy

 

EQ-5D utility score model

EQ-5D dimension model

PROPr

model

PROMIS dimension model

EQ-5D

    

Utility score

-13.05(-29.66,3.56)

002D

–

–

Mobility

–

-1.34(-4.9,2.23)

–

–

Self-care

–

1.98(-1.39,5.35)

–

–

Usual activities

–

2.45(-1.15,6.05)

–

–

Pain/Discomfort

–

0.55(-1.88,2.98)

–

–

Anxiety/depression

–

0.98(-1.55,3.51)

–

–

PROMIS

–

–

–

–

PROPr

–

–

57.04(33, 81.1)

–

Anxiety/Fear

–

–

–

-2.42(-49.91,45.07)

Cognition

–

–

–

-0.32(-8.18,7.55)

Depression/Sadness

–

–

–

1.79(-23.28,26.85)

Fatigue

–

–

–

-0.87(-1.59,-0.15)

Pain intensity VAS

–

–

–

-1.63(-37.38,34.12)

Pain interference

–

–

–

0.52(-10.37,11.41)

Physical function

–

–

–

-0.14(-0.73,0.46)

Sleep disturbance

–

–

–

-3.4(-82.54,75.74)

Social roles and activities

–

–

–

0.8(-12.04,13.64)

Gender - Male

-2.35(-10.54,5.83)

-2.93(-11.13,5.26)

-3.73(-11.39,3.93)

-5.89(-13.62,1.84)

Age

-0.11(-0.71,0.49)

-0.11(-0.72,0.51)

-0.11(-0.67,0.45)

-0.08(-0.62,0.47)

Duration

-0.05(-0.46,0.35)

-0.09(-0.5,0.33)

0.04(-0.34,0.42)

0.08(-0.31,0.47)

Type T2

-6.72(-15.75,2.31)

-12.79(-23.3,-2.27)

-8.81(-17.15,-0.47)

-9.21(-18.44,0.01)

Type T3

20.66(-7.6,48.93)

8.77(-21.39,38.93)

16.34(-9.97,42.64)

14.42(-11.81,40.65)

Adjuste R2

0.03

0.03

0.15

0.2

BIC

1273.56

1287.74

1254.66

1277.28