From: Measurement properties of the EQ-5D-5L and PROPr in patients with spinal muscular atrophy
Variable | Ceiling effect (%) | Floor effect (%) | Mean | Standard deviation | Median | Range |
---|---|---|---|---|---|---|
EQ-5D-5L dimensions | Â | Â | Â | Â | Â | Â |
Mobility | 11.7 | 65.7 | – | – | – | – |
Self-care | 49.6 | 22.6 | – | – | – | – |
Usual activities | 29.2 | 8 | – | – | – | – |
Pain/discomfort | 30.7 | 47.4 | – | – | – | – |
Anxiety/Depression | 35.8 | 28.5 | – | – | – | – |
Best health (11,111) | 0.0 | – | – | – | – | – |
Worst health (55,555) | – | 0.0 | – | – | – | – |
EQ-5D utility score | 0.7 | 0.7 | 0.27 | 0.25 | 0.3 | -0.35–0.75 |
EQ-VAS | 1.5 | 2.2 | 57.6 | 23.5 | 57.5 | 7 ~ 100 |
PROMIS-29 subscales | Â | Â | Â | Â | Â | Â |
Anxiety/Fear | 0.7 | 16.8 | 57.7 | 10.3 | 57.5 | 40.3–81.4 |
Cognition | 0.7 | 0.7 | 49.9 | 9.9 | 49.3 | 25.2–75.9 |
Depression/Sadness | 3.6 | 18.2 | 58.2 | 10.6 | 58.9 | 41–79.3 |
Fatigue | 2.2 | 3.6 | 54.4 | 8.9 | 53.2 | 33.7–75.8 |
Pain intensity VAS | 0.7 | 27 | 2.4 | 2.3 | 2 | 0–10 |
Pain interference | 2.2 | 32.1 | 53.5 | 9.6 | 55.7 | 41.6–75.6 |
Physical function | 2.2 | 45.3 | 29.1 | 8.2 | 26.5 | 22.6–57 |
Sleep disturbance | 0.7 | 2.9 | 49.3 | 6.5 | 50.1 | 32–63.9 |
Social roles and activities | 2.9 | 15.3 | 41.3 | 9.1 | 40.3 | 27.5–64.2 |
PROPr | 0.7 | 0.7 | 0.25 | 0.16 | 0.22 | 0.04–0.93 |