Table 6 Factors associated with the changes of EQ-5D-Y and PedsQL scores/subscales among those who completed both initial and latest follow-up assessments across times (T2-T1) (n = 83)
Variables | PedsQL | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ΔPhysical Health | ΔEmotional | ΔSocial | ΔSchool | |||||||||||||
β* | 95% CI | p-value | β* | 95% CI | p-value | β* | 95% CI | p-value | β* | 95% CI | p-value | |||||
Intercept | 98.15 | 93.60 | 102.70 | < .0001 | 87.63 | 79.46 | 95.79 | < .0001 | 96.43 | 92.95 | 99.91 | < .0001 | 100.58 | 93.84 | 107.31 | < .0001 |
Time (every 6 months) | 0.68 | 0.40 | 0.96 | < .0001 | 1.13 | 0.71 | 1.55 | < .0001 | 0.51 | 0.26 | 0.77 | < .0001 | 0.89 | 0.50 | 1.27 | < .0001 |
Aged 13–18 years (vs 7–12) | -0.98 | -3.17 | 1.21 | 0.3745 | -0.19 | -4.12 | 3.75 | 0.9249 | 2.14 | 0.47 | 3.81 | 0.0131 | 1.53 | -1.72 | 4.78 | 0.3488 |
Boys (vs Girls) | 0.08 | -1.83 | 2.00 | 0.9299 | -0.79 | -4.26 | 2.69 | 0.6507 | -0.52 | -1.97 | 0.93 | 0.4732 | -3.17 | -6.02 | -0.31 | 0.0303 |
Baseline eGFR | -0.02 | -0.06 | 0.01 | 0.1889 | 0.01 | -0.05 | 0.07 | 0.7127 | -0.01 | -0.03 | 0.02 | 0.5843 | -0.07 | -0.12 | -0.02 | 0.0059 |
Change in eGFR, per month | -1.76 | -2.76 | -0.76 | 0.0009 | -0.94 | -2.72 | 0.84 | 0.2964 | -1.05 | -1.83 | -0.28 | 0.0084 | -2.16 | -3.64 | -0.69 | 0.0048 |
Number of comorbidities at T1(vs none) | ||||||||||||||||
1 | 0.17 | -3.58 | 3.91 | 0.9297 | 0.24 | -6.52 | 7.01 | 0.9425 | -0.79 | -3.64 | 2.05 | 0.5785 | -2.44 | -8.00 | 3.13 | 0.3838 |
2 | 1.60 | -4.67 | 7.88 | 0.6110 | -3.96 | -15.28 | 7.35 | 0.4857 | -1.72 | -6.50 | 3.05 | 0.4726 | -8.23 | -17.54 | 1.08 | 0.0821 |
≥ 3 | -3.05 | -13.20 | 7.09 | 0.5489 | -10.67 | -28.82 | 7.48 | 0.2435 | -3.24 | -11.04 | 4.56 | 0.4084 | -12.70 | -27.70 | 2.30 | 0.0954 |
Change in comorbidity (vs no–no at T1&T2) | ||||||||||||||||
Growth retardation | ||||||||||||||||
baseline ( +) & latest (-) | 2.65 | -3.00 | 8.30 | 0.3514 | 6.59 | -3.67 | 16.85 | 0.2032 | 6.23 | 1.97 | 10.48 | 0.0049 | 0.55 | -7.86 | 8.97 | 0.8959 |
baseline ( +) & latest ( +) | -3.88 | -8.89 | 1.13 | 0.1267 | 3.62 | -5.35 | 12.60 | 0.4217 | -2.10 | -5.95 | 1.75 | 0.2781 | -3.73 | -11.15 | 3.68 | 0.3172 |
baseline (-) & latest ( +) | -2.73 | -6.31 | 0.84 | 0.1309 | -0.71 | -7.23 | 5.81 | 0.8281 | -2.75 | -5.43 | -0.07 | 0.0443 | -2.78 | -8.11 | 2.55 | 0.3008 |
Overweight | ||||||||||||||||
baseline ( +) & latest (-) | 0.46 | -4.76 | 5.69 | 0.8599 | 4.41 | -4.91 | 13.73 | 0.3473 | 3.83 | -0.20 | 7.87 | 0.0623 | 4.82 | -2.89 | 12.54 | 0.2156 |
baseline ( +) & latest ( +) | 3.22 | -0.34 | 6.79 | 0.0756 | 6.79 | 0.39 | 13.20 | 0.0381 | 3.10 | 0.38 | 5.83 | 0.0264 | 6.07 | 0.78 | 11.35 | 0.0252 |
baseline (-) & latest ( +) | 1.33 | -2.07 | 4.72 | 0.4365 | 4.09 | -2.07 | 10.26 | 0.1889 | 0.17 | -2.38 | 2.72 | 0.8915 | -1.17 | -6.23 | 3.88 | 0.6432 |
Hypertension | ||||||||||||||||
baseline ( +) & latest (-) | -1.49 | -6.03 | 3.06 | 0.5151 | 4.37 | -3.87 | 12.61 | 0.2927 | 1.91 | -1.53 | 5.34 | 0.2713 | 4.75 | -2.02 | 11.51 | 0.1653 |
baseline ( +) & latest ( +) | -1.00 | -4.66 | 2.66 | 0.5872 | -0.42 | -6.99 | 6.14 | 0.8981 | -0.74 | -3.54 | 2.07 | 0.5997 | -0.42 | -5.84 | 5.00 | 0.8763 |
baseline (-) & latest ( +) | -2.53 | -4.91 | -0.15 | 0.0375 | -2.45 | -6.74 | 1.84 | 0.2575 | 0.24 | -1.57 | 2.05 | 0.7923 | -4.26 | -7.79 | -0.73 | 0.0190 |
Hyperlipidemia | ||||||||||||||||
baseline ( +) & latest (-) | 1.55 | -5.66 | 8.76 | 0.6677 | -3.27 | -16.05 | 9.52 | 0.6104 | 2.94 | -2.67 | 8.55 | 0.2975 | -3.08 | -13.70 | 7.53 | 0.5630 |
baseline ( +) & latest ( +) | -0.71 | -4.51 | 3.10 | 0.7112 | 0.01 | -6.87 | 6.88 | 0.9987 | 1.95 | -0.93 | 4.84 | 0.1799 | -0.91 | -6.56 | 4.74 | 0.7484 |
baseline (-) & latest ( +) | -0.46 | -4.51 | 3.59 | 0.8198 | 1.41 | -5.91 | 8.74 | 0.7004 | 2.71 | -0.36 | 5.78 | 0.0828 | 6.10 | 0.08 | 12.12 | 0.0470 |
Mineral bone disorders/Anemia | ||||||||||||||||
baseline ( +) & latest (-) | -0.01 | -5.00 | 4.98 | 0.9955 | 0.13 | -8.90 | 9.15 | 0.9778 | -0.30 | -4.08 | 3.48 | 0.8745 | -4.42 | -11.84 | 3.00 | 0.2373 |
baseline ( +) & latest ( +) | -6.88 | -12.37 | -1.40 | 0.0149 | -6.13 | -16.00 | 3.74 | 0.2181 | 0.72 | -3.46 | 4.90 | 0.7309 | -12.90 | -21.04 | -4.77 | 0.0024 |
baseline (-) & latest ( +) | -2.68 | -6.39 | 1.03 | 0.1530 | -2.88 | -9.58 | 3.81 | 0.3918 | -2.43 | -5.24 | 0.38 | 0.0884 | -5.47 | -10.98 | 0.03 | 0.0513 |
Hyperuricemia | ||||||||||||||||
baseline ( +) & latest (-) | -3.79 | -8.54 | 0.95 | 0.1150 | 1.49 | -7.04 | 10.03 | 0.7270 | 0.82 | -2.80 | 4.44 | 0.6525 | 0.53 | -6.51 | 7.56 | 0.8807 |
baseline ( +) & latest ( +) | -1.37 | -5.47 | 2.73 | 0.5049 | 4.35 | -2.98 | 11.69 | 0.2395 | -2.35 | -5.50 | 0.80 | 0.1400 | 4.62 | -1.45 | 10.68 | 0.1328 |
baseline (-) & latest ( +) | -2.25 | -4.96 | 0.46 | 0.1022 | -3.14 | -8.05 | 1.76 | 0.2043 | -3.00 | -5.05 | -0.94 | 0.0050 | -5.23 | -9.26 | -1.19 | 0.0120 |
Proteinuria | ||||||||||||||||
baseline ( +) & latest (-) | -5.30 | -9.64 | -0.96 | 0.0177 | 2.74 | -5.07 | 10.54 | 0.4850 | -4.70 | -8.01 | -1.38 | 0.0063 | -1.56 | -7.99 | 4.88 | 0.6300 |
baseline ( +) & latest ( +) | 1.42 | -2.53 | 5.38 | 0.4732 | 6.36 | -0.76 | 13.47 | 0.0790 | 1.42 | -1.60 | 4.43 | 0.3502 | 2.92 | -2.94 | 8.78 | 0.3225 |
baseline (-) & latest ( +) | -2.31 | -6.73 | 2.11 | 0.2995 | 3.95 | -4.03 | 11.92 | 0.3252 | -0.14 | -3.49 | 3.21 | 0.9343 | 4.67 | -1.89 | 11.23 | 0.1590 |