Table 1 Baseline Characteristics for South Africa and Uganda for individuals failing first line antiretroviral therapies (viral load > 1,000 copies/mL)

Sample size (n)

420

420

Age (years) (mean, SD)

38.1 (9.4)

38.5 (11.0)

0.558

Males (n, %)

228 (54.3%)

182 (43.3%)

0.001

Viral load (copies/1,000 mm³) (n, %)

≤ 50,000

294 (70.0%)

316 (75.2%)

0.089

> 50,000

126 (30.0%)

104 (24.8%)

CD4 count (cells per mm³) (n, %)

<200

186 (44.8%)

108 (29.7%)

< 0.001

200–499

173 (41.7%)

150 (41.2%)

≥500

56 (13.5%)

106 (29.1%)

missing

5

56

Comorbidities (n, %)

Yes

169 (40.4%)

106 (25.7%)

< 0.001

No

249 (59.6%)

306 (74.3%)

missing

2

8

Opportunistic infection (n, %)

Yes

214 (51.0%)

67 (16.1%)

< 0.001

No

206 (49.0%)

349 (83.9%)

missing

0

4

Side effects (n, %)

Yes

57 (13.6%)

66 (15.7%)

0.388

No

362 (86.4%)

354 (84.3%)

missing

1

0

Adherence (n, %)

Yes

157 (37.4%)

91 (21.7%)

< 0.001

No

263 (62.6%)

328 (78.3%)

missing

0

1

EQ-5D-3 L utility

Median (IQR)

1 (0.146)

1 (0.402)

< 0.001

Mean (SD)

0.894 (0.175)

0.830 (0.214)

< 0.001