Table 5 Comparison of effect sizes from VitiQoL, VNS, EQ-5D and RPS
HRQoL Instrument | Response Category | Total VitiQoL | EQ-5D (Van Hout) | EQ-5D (Alava) | |
|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | |||
9 Months | VNS | 1: More Noticeable | 37.22 (23.22) | 0.900 (0.145) | 0.899 (0.124) |
2: As Noticeable | 34.61 (22.28) | 0.893 (0.168) | 0.886 (0.170) | ||
3: Slightly Less Noticeable | 34.43 (23.22) | 0.909 (0.154) | 0.898 (0.164) | ||
4: A lot Less Noticeable | 30.26 (20.89) | 0.917 (0.131) | 0.905 (0.145) | ||
5: No Longer Noticeable | 29.73 (24.76) | 0.951 (0.108) | 0.937 (0.114) | ||
Responder# | 30.18 (21.36) | 0.922 (0.127) | 0.910 (0.140) | ||
Non-Responder | 35.18 (22.80) | 0.901 (0.157) | 0.893 (0.157) | ||
Differencea (95% CI; p-value) | -5.01 (-11.09, 1.08) p = 0.107 | 0.022 (-0.016, -0.012) p = 0.258 | 0.017 (-0.022, 0.055) p = 0.394 | ||
Baseline | RPS (%) | < 25 | 35.54 (24.28) | 0.896 (0.174) | 0.894 (0.166) |
25 to 49 | 38.35 (22.67) | 0.945 (0.071) | 0.943 (0.058) | ||
50–74 | 34.90 (17.18) | 0.914 (0.108) | 0.900 (0.111) | ||
75–100 | 32.00 (28.67) | 0.921 (0.126) | 0.915 (0.125) | ||
9 Months | RPS (%) | < 25 | 34.63 (22.62) | 0.895 (0.167) | 0.887 (0.168) |
25 to 49 | 37.13 (24.82) | 0.923 (0.084) | 0.916 (0.080) | ||
50–74 | 29.14 (19.83) | 0.908 (0.141) | 0.896 (0.159) | ||
75–100 | 32.18 (22.06) | 0.951 (0.103) | 0.941 (0.104) | ||
Responder (≥ 75) | 30.45 (20.71) | 0.927 (0.127) | 0.916 (0.139) | ||
Non-Responder | 35.05 (22.97) | 0.899 (0.157) | 0.891 (0.157) | ||
Differencea (95% CI; p-value) | -4.60 (-10.79, 1.59) p = 0.145 | 0.027 (-0.011, 0.065) p = 0.157 | 0.024 (-0.014, 0.063) p = 0.217 |