Characteristic | Lower extremity | Upper extremity | Overall (%) | ||
---|---|---|---|---|---|
Pediatric (%) | Adult survivors (%) | Pediatric (%) | Adult survivors (%) | ||
Eligible | 134 | 53 | 36 | 10 | 233 |
Median age, years | 14.3 (8–17.9) | 20.6 (18–32) | 13.3 (8–17.9) | 20.8 (18–24) | 15.6 (8–32) |
Gender | |||||
 Male | 70 (52) | 27 (51) | 14 (39)) | 5 (50) | 116 (50) |
 Female | 64 (48) | 26 (49) | 22 (61) | 5 (50) | 117 (50) |
Diagnosis | |||||
 Osteosarcoma | 91 (68) | 41 (77) | 9 (25) | 4 (40) | 145 (62) |
 Ewing sarcoma | 43 (32) | 12 (33) | 27 (75) | 6 (60) | 88 (38) |
Component | |||||
 Osseous | 132 (99) | 53 (100) | 33 (92) | 8 (80) | 226 (97) |
 Extra-osseous | 2 (1) | 0 | 3 (8) | 2 (20) | 7 (3) |
Tumor location | |||||
 Tibia | 24 (18) | 18 (34) | 0 | 0 | 42 (18) |
 Femur | 94 (70) | 31 (58) | 0 | 0 | 125 (54) |
 Fibula | 13 (10) | 4 (8) | 0 | 0 | 17 (7) |
 Talus/Calcaneous | 3 (2) | 0 | 0 | 0 | 3 (1.5) |
 Humerus | 0 | 0 | 19 (53) | 8 (80) | 27 (11.5) |
 Radius/ulna | 0 | 0 | 3 (8) | 0 | 3 (1.5) |
 Scapula | 0 | 0 | 9 (25) | 2 (20) | 11 (5) |
 Shoulder/Clavicle | 0 | 0 | 3 (8) | 0 | 3 (1.5) |
 Metacarpal | 0 | 0 | 2 (6) | 0 | 2 (1) |
Months from surgery | 27.8 (3–156) | 73.7 (3–169) | 31 (3–135) | 71.1 (25–112) | 38 (3–169) |
Type of LC | |||||
 Surgery | 130 (97) | 50 (94) | 27 (75) | 7 (70) | 214 (92) |
 Surgery +RTH | 4 (3) | 3 (6) | 0 | 1 (10) | 8 (3) |
 ECI | 0 | 0 | 9 (25) | 2 (20) | 11 (5) |
Type of surgery | |||||
 Amputation | 3 (2) | 1 (2) | 1 (3) | 0 | 5 (2) |
 Rotationplasty | 2 (1.5) | 0 | 0 | 0 | 2 (1) |
 Limb salvage | 129 (96.5) | 52 (98) | 26 (72) | 8 (80) | 215 (92) |
  Prosthesis | 76 (59) | 35 (67) | 7 (27) | 3 (37) | 121 (56) |
  VFG | 29 (22) | 14 (27) | 5 (19) | 5 (63) | 53 (25) |
  Non-VFG | 0 | 0 | 2 (7) | 0 | 2 (1) |
  Spacer/fixation | 9 (7) | 0 | 9 (35) | 0 | 18 (8) |
  Fibulectomy/resection | 15 (12) | 3 (6) | 3 (12) | 0 | 21 (10) |
Chemotherapy status | |||||
 On treatment/end <1 month | 23 (17) | 1 (2) | 5 (14) | 0 | 29 (12) |
 Finished treatment | 111 (83) | 52 (98) | 31 (86) | 10 (100) | 204 (88) |