Table 1 Socio-demographic, cognitive and clinical features of the severe Alcohol Use Disorder (sAUD) patients and Healthy Controls (HC).

SOCIO-DEMOGRAPHIC

Age (years)

46.15 ± 10.13

44.34 ± 6.07

p = 0.33

Gender, men (%)

86.79%

94.73%

p = 0.21

Education (years)

11.32 ± 2.09

11.82 ± 0.73

p = 0.12

Living status, living alone (%)

54.72%

34.21%

p = 0.05

COGNITIVE

Episodic memory (z-score)

-1.55 ± 1.22

0 ± 1

HC > sAUD^*

Working memory (z-score)

-1.27 ± 0.82

0 ± 1

HC > sAUD^*

Executive functions (z-score)

-1.08 ± 1.49

0 ± 1

HC > sAUD^*

Processing speed (z-score)

-1.57 ± 1.65

0 ± 1

HC > sAUD^*

CLINICAL

Sleep

PSQI

8.74 ± 3.27 (2MD)

2.37 ± 1.51

HC < sAUD^*

Depression and anxiety

BDI

17.30 ± 10.91 (1MD)

2.89 ± 3.09

HC < sAUD^*

STAI B (trait anxiety)

51.21 ± 10.62

32.16 ± 6.87

HC < sAUD^*

Impulsivity

S-UPPS-P

48.45 ± 10.99

33.24 ± 11.15

HC < sAUD^*

Negative Urgency

10.38 ± 3.41

7.13 ± 3.23

HC < sAUD^*

Lack of Premeditation

8.98 ± 2.54

6.24 ± 2.11

HC < sAUD^*

Lack of perseverance

8.32 ± 2.92

5.68 ± 1.95

HC < sAUD^*

Sensation Seeking

10.64 ± 8.04

6.79 ± 2.36

HC < sAUD^*

Positive Urgency

11.43 ± 2.94

7.5 ± 3.35

HC < sAUD^*

Alcohol history

AUDIT

28.58 ± 5.75

2.42 ± 1.64

HC < sAUD^*

Age of onset of AUD (years)

31.30 ± 8.87 (3MD)

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Daily alcohol consumption during the month preceding withdrawal (units ^a)

19.30 ± 7.01 (1MD)

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