Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation

Table 2 Regression Analysis

DV	IV	b	SE	t-value	P	sr
ppFEV₁	BMI	1.37	0.65	2.12	0.04	0.22
	Cough suppression dummy 1	0.98	6.77	0.15	0.89	–
	Cough suppression dummy 2	8.95	9.23	0.97	0.34	–
	Future perspectives dummy 1	12.31	6.66	1.85	0.07	–
	Future perspectives dummy 2	20.36	7.82	2.61	0.01	0.27
	Cough suppresion x sex dummy 1	17.43	10.93	1.59	0.12	–
	Cough suppresion x sex dummy 2	− 0.55	11.80	− 0.05	0.96	–
BMI	ppFEV1	0.04	0.02	1.79	0.08	–
	Cough suppression dummy 1	0.93	1.23	0.76	0.45	–
	Cough suppression dummy 2	1.04	1.69	0.61	0.54	–
	Future perspectives dummy 1	0.30	1.25	0.24	0.81	–
	Future perspectives dummy 2	0.23	1.51	0.15	0.88	–
	Cough suppresion x sex dummy 1	− 1.12	2.04	− 0.55	0.59	–
	Cough suppresion x sex dummy 2	− 0.52	2.16	− 0.24	0.81	–
HRQoL—total score	ppFEV1	3.10	1.28	2.41	0.02	0.26
	Cough suppression dummy 1	− 74.68	72.12	− 1.04	0.31	–
	Cough suppression dummy 2	− 242.48	102.94	− 2.36	0.02	− 0.25
	Future perspectives dummy 1	− 43.53	72.88	− 0.60	0.55	–
	Future perspectives dummy 2	147.29	83.17	1.77	0.08	–
	Cough suppresion x sex dummy 1	72.55	116.17	0.62	0.54	–
	Cough suppresion x sex dummy 2	101.90	130.78	0.78	0.44	–
Future perspectives	ppFEV1	0.02	9 × 10–3	4.20	0.04	–
	Cough suppression dummy 1	0.05	0.44	0.01	0.92	–
	Cough suppression dummy 2	− 0.65	0.61	1.13	0.29	–
	Cough suppresion x sex dummy 1	1.38	0.80	2.98	0.09	–
	Cough suppresion x sex dummy 2	0.44	0.89	0.25	0.62	–

Regression results regarding the dependent variable (DV) outlined in the respective row. ppFEV₁ = predicted forced expiratory volume in one second, HRQoL = health-related quality of life, b = unstandardized regression coefficient, SE = standard error, sr = semi-partial correlation (only reported regarding multiple regression results and significant findings). Cough suppression: dummy 1 [never/rarely vs. occasionally], dummy 2 [never/rarely vs. often/always]; future perspectives: dummy 1 [moderate vs. bad], dummy 2 [good vs. bad]; interaction between cough suppression and sex: dummy 1 [females vs. males—never/rarely vs. occasionally], dummy 2 [females vs. males—never/rarely vs. often/always]. Significant findings are printed in bold type. Note, ppFEV₁ and BMI were transformed due to non-normality. Covariates adjusted for in addition to listed predictors: ppFEV₁—sex, P. aeruginosa status, sputum quantity; BMI—age, sex, genotype (homo- vs. heterozygous), employment status; HRQoL—sex, ppFEV₁; future perspectives—sex, sputum quantity, ppFEV₁

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