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Table 1 Patient demographic und clinical characteristics, n = 71

From: Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation

 

All subjects (n = 71)

Male (n = 41)

Female (n = 30)

Age, years

32.52 ± 11.68 (18–71)

35.12 ± 12.64* (19–71)

28.97 ± 9.28 (18–52)

Sex

 

41 (58)

30 (42)

Genotype n, (%)

F508del homozygous

28 (39)

12 (29)

16 (53)

F508del heterozygous

31 (44)

21 (51)

10 (33)

Other

12 (17)

8 (20)

4 (13)

BMI, kg/m2

20.27 ± 3.42 (15–33)

21.22 ± 3,68* (16–33)

19.97 ± 2.54 (15–25)

ppFEV1

43.17 ± 19.80 (16–99)

45.95 ± 21,26 (20–99)

39.37 ± 17.23 (16–82)

Pancreatic insufficiency n, %

46 (65)

22 (54)*

24 (80)

CF-related diabetes n, %

22 (31)

16 (39)

6 (20)

P. aeruginosa positive n, %

52 (73)

30 (73)

22 (73)

Hospital n, %

Inpatient

68 (96)

39 (95)

29 (97)

Outpatient

3 (4)

2 (5)

1 (3)

Reasons for medical treatment n, %

PEX

34 (48)

18 (44)

16 (53)

Starting CFTR-modulator therapy

14 (20)

11(27)

3 (10)

IVAT

8 (11)

4 (10)

4 (13)

Others

15 (21)

8 (20)

7 (23)

Diagnosis disclosure n, %

Family

70 (99)

40 (98)

30 (100)

Friends

49 (70)

30 (73)

19 (66)

Employer

32 (78)

20 (83)

12 (71)

Colleagues

15 (37)

9 (38)

6 (35)

  1. Results are presented as mean ± and standard deviation (SD) and range or number of pwCF n (%), ppFEV1—percent predicted forced expiratory volume in one second, PEX—pulmonary exacerbation; IVAT – intravenous antibiotic therapy (prophylactic). * Significant difference between sexes