The FACT-8D, a new cancer-specific utility algorithm based on the Functional Assessment of Cancer Therapies-General (FACT-G): a Canadian valuation study

McTaggart-Cowan, Helen; King, Madeleine T.; Norman, Richard; Costa, Daniel S. J.; Pickard, A. Simon; Viney, Rosalie; Peacock, Stuart J.

doi:10.1186/s12955-022-02002-z

Table 4 Conditional logit results: Model 1 (unconstrained), Model 2 (raked and unconstrained), and Model 3 (montonicity imposed)

From: The FACT-8D, a new cancer-specific utility algorithm based on the Functional Assessment of Cancer Therapies-General (FACT-G): a Canadian valuation study

Mean		Model 1	Model 2	Model 3
Mean		Coefficient^a (robust SE)	Coefficient^a (robust SE)	Coefficient^a (robust SE)
Duration	Linear	0.331 (0.013)***	0.345 (0.026)***	0.366 (0.023)***
Pain × Duration^a	2	0.003 (0.007)	0.014 (0.012)	0
	3	− 0.020 (0.008)**	− 0.025 (0.018)***	− 0.021 (0.015)
	4	− 0.060 (0.008)***	− 0.062 (0.015)***	− 0.072 (0.014)***
	5	− 0.136 (0.007)***	− 0.148 (0.015)***	− 0.149 (0.014)***
Fatigue × Duration^a	2	− 0.002 (0.007)	− 0.030 (0.013)**	− 0.020 (0.011)
	3	− 0.021 (0.006)***	− 0.038 (0.013)***	− 0.028 (0.011)**
	4	− 0.040 (0.007)***	− 0.048 (0.015)***	− 0.053 (0.014)***
	5	− 0.050 (0.007)***	− 0.069 (0.013)***	− 0.060 (0.012)***
Nausea × Duration^a	2	− 0.032 (0.006)***	− 0.036 (0.013)***	− 0.036 (0.011)***
	3	− 0.044 (0.006)***	− 0.047 (0.011)***	− 0.055 (0.011)***
	4	− 0.061 (0.006)***	− 0.063 (0.013)***	− 0.059 (0.012)***
	5	− 0.089 (0.008)***	− 0.103 (0.015)***	− 0.109 (0.014)***
Sleep × Duration^a	2	0.020 (0.006)***	0.024 (0.012)**	0
	3	0.015 (0.007)**	0.036 (0.015)**	0
	4	− 0.040 (0.006)***	− 0.019 (0.013)	− 0.028 (0.008)***
	5	− 0.006 (0.007)	0.010 (0.015)	− 0.028 (0.008)***
Work × Duration^a	2	− 0.009 (0.008)	− 0.026 (0.016)	− 0.021 (0.014)
	3	− 0.014 (0.006)**	− 0.040 (0.016)**	− 0.033 (0.011)***
	4	− 0.034 (0.007)***	− 0.039 (0.013)***	− 0.033 (0.011)***
	5	− 0.076 (0.006)***	− 0.088 (0.013)***	− 0.085 (0.012)***
Support × Duration^a	2	− 0.023 (0.007)***	− 0.034 (0.012)***	− 0.008 (0.008)
	3	− 0.001 (0.006)	0.009 (0.012)***	− 0.008 (0.008)
	4	− 0.045 (0.006)***	− 0.038 (0.013)***	− 0.044 (0.012)***
	5	− 0.067 (0.006)***	− 0.064 (0.011)***	− 0.072 (0.010)***
Sadness × Duration^a	2	− 0.009 (0.007)	0.001 (0.012)	0
	3	− 0.035 (0.007)***	− 0.050 (0.014)***	− 0.047 (0.010)***
	4	− 0.038 (0.006)***	− 0.035 (0.013)***	− 0.047 (0.010)***
	5	− 0.058 (0.007)***	− 0.069 (0.013)***	− 0.068 (0.012)***
Worry my health will get worse × Duration^a	2	− 0.031 (0.006)***	− 0.046 (0.011)***	− 0.035 (0.010)***
	3	− 0.019 (0.007)***	− 0.021 (0.012)	− 0.035 (0.010)***
	4	− 0.039 (0.007)***	− 0.050 (0.014)***	− 0.043 (0.011)***
	5	− 0.049 (0.007)***	− 0.033 (0.015)***	− 0.043 (0.011)***
Log-likelihood		− 15,009.31	− 14,602.54	− 14,655.46
Parameters		33	33	23
AIC		30,084.62	29,271.07	29,540.03
BIC		30,375.13	29,560.89	29,724.46

^aThe coefficient for each level of each dimension was estimated as the interaction of that level with duration
Levels of statistical significant: ***1%; **5%
AIC Akaike information criterion, BIC Bayesian information criterion

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