| |
Baseline LSS
|
24 h LSS
|
Paired differences
|
|---|
| |
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
p
|
Effect Size (95% CI)
|
|---|
|
All (n = 77)
| | | | | |
|
EQ-5D-Y-5L
|
13.64 (3.93)
|
12.36 (3.89)
|
1.27 (3.01)
|
< 0.001
|
0.43 (0.19, 0.66)
|
|
EQ-5D-Y-3L
|
9.55 (2.21)
|
8.77 (2.05)
|
0.78 (1.93)
|
< 0.001
|
0.40 (0.17, 0.64)
|
|
No change (n = 43)
| | | | | |
|
EQ-5D-Y-5L
|
13.56 (3.57)
|
12.79 (3.18)
|
0.67 (2.83)
|
0.126
|
0.24 (− 0.07, 0.54)
|
|
EQ-5D-Y-3L
|
9.42 (2.28)
|
8.84 (1.80)
|
0.58 (1.78)
|
0.038
|
0.33 (0.02, 0.63)
|
|
Improve (n = 22)
| | | | | |
|
EQ-5D-Y-5L
|
13.82 (4.54)
|
11.09 (4.42)
|
2.73 (2.91)
|
< 0.001
|
0.94 (0.42, 1.43)
|
|
EQ-5D-Y-3L
|
10.00 (1.98)
|
8.45 (2.37)
|
1.55 (2.30)
|
0.005
|
0.67 (0.20, 1.13)
|
|
Worsen (n = 12)
| | | | | |
|
EQ-5D-Y-5L
|
13.58 (4.32)
|
12.83 (4.59)
|
0.75 (3.11)
|
0.421
|
0.24 (− 0.34, 0.81)
|
|
EQ-5D-Y-3L
|
9.17 (2.44)
|
9.08 (2.39)
|
0.08 (1.31)
|
0.830
|
0.06 (− 0.50, 0.63)
|
| |
24 h LSS
|
48 h LSS
| |
|---|
|
All (n = 71)
| | | | | |
|
EQ-5D-Y-5L
|
12.38 (3.79)
|
11.51 (3.76)
|
0.87 (3.15)
|
0.022
|
0.28 (0.04, 0.51)
|
|
EQ-5D-Y-3L
|
8.82 (2.00)
|
8.51 (1.97)
|
0.31 (1.70)
|
0.128
|
0.18 (− 0.05, 0.41)
|
|
No change (n = 42)
| | | | | |
|
EQ-5D-Y-5L
|
13.62 (4.22)
|
12.55 (3.83,0.59)
|
1.07 (3.10)
|
0.031
|
0.35 (0.03,0.66)
|
|
EQ-5D-Y-3L
|
9.50 (2.17)
|
8.90 (1.97)
|
0.60 (1.98)
|
0.058
|
0.30 (− 0.01,0.61)
|
|
Improve (n = 20)
| | | | | |
|
EQ-5D-Y-5L
|
13.30 (4.18)
|
12.20 (3.74)
|
1.10 (2.92)
|
0.108
|
0.38 (− 0.08, 0.82)
|
|
EQ-5D-Y-3L
|
9.20 (2.44)
|
8.60 (2.06)
|
0.60 (1.76)
|
0.144
|
0.34 (− 0.11, 0.79)
|
|
Worsen (n = 9)
| | | | | |
|
EQ-5D-Y-5L
|
12.00 (4.12)
|
13.22 (4.49)
|
− 1.22 (3.70)
|
0.351
|
− 0.33 (− 0.99,0.35)
|
|
EQ-5D-Y-3L
|
8.89 (2.09)
|
9.22 (1.92)
|
− 0.33 (1.12)
|
0.397
|
− 0.30 (− 0.96,0.38)
|
| |
Baseline LSS
|
48 h LSS
| |
|---|
|
All (n = 71)
| | | | | |
|
EQ-5D-Y-5L
|
13.56 (4.01)
|
8.51 (1.97)
|
5.06 (3.45)
|
< 0.001
|
1.46 (1.12, 1.79)
|
|
EQ-5D-Y-3L
|
9.58 (2.19)
|
8.51 (1.97)
|
1.07 (2.08)
|
< 0.001
|
0.52 (0.26, 0.76)
|
|
No change (n = 32)
| | | | | |
|
EQ-5D-Y-5L
|
13.66 (3.21)
|
11.84 (3.49)
|
1.81 (3.41)
|
0.005
|
0.53 (0.16, 0.90)
|
|
EQ-5D-Y-3L
|
9.69 (1.75)
|
8.81 (1.96)
|
0.88 (2.11)
|
0.025
|
0.42 (0.05, 0.77)
|
|
Improve (n = 29)
| | | | | |
|
EQ-5D-Y-5L
|
13.69 (4.89)
|
11.34 (3.88)
|
2.35 (3.78)
|
0.002
|
0.62 (0.22,1.01)
|
|
EQ-5D-Y-3L
|
9.55 (2.47)
|
8.17 (1.98)
|
1.38 (2.13)
|
0.002
|
0.65 (0.24, 1.05)
|
|
Worsen (n = 10)
| | | | | |
|
EQ-5D-Y-5L
|
12.90 (3.81)
|
10.9 (4.53)
|
2.00 (3.68)
|
0.120
|
0.54 (− 0.13, 1.20)
|
|
EQ-5D-Y-3L
|
9.30 (2.75)
|
8.50 (2.01)
|
0.80 (1.93)
|
0.223
|
0.41 (− 0.24, 1.05)
|
- Calculated using EQ-5D-Y-3L/ EQ-5D-5L level sum scores (LSS), a higher score indicates a worse health state, LSS, level sum score; SD, standard deviation; CI, Confidence Interval
