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Table 1 Demographic and clinical characteristics

From: Depression, anxiety and health-related quality of life in paediatric intracranial germ cell tumor survivors

  n %   n %
Total participants 200 100 Treatment method (non-recurrent)   
Recurrence    Irradiation type   
 Yes 10 10.0  Local 3 1.7
 No 180 90.0  WBI 138 76.6
Clinical data (non-recurrent)     CSI 39 21.7
Gender    Radiation dose, Gy   
 Female 56 31.1  Low (< 50) 114 63.3
 Male 124 68.9  High (≥ 50) 66 36.7
Diagnosis    Surgery type   
 GCT 131 72.8  No surgery 134 74.4
 NGGCT 49 27.2  Biopsy only 9 5.0
β-HCG range     Definitive surgery 37 20.6
 Normal    Chemotherapy   
 High 105 58.3  Yes 177 98.3
AFP range 75 41.7  No 3 1.7
 Normal    Depression/anxiety   
 High 156 86.7 Child depression   
Tumor location 24 13.3  Healthy (CDI < 19) 86 92.5
 Suprasellar region     Depression (CDI ≥ 19) 7 7.5
 Pineal region 50 27.7 Child anxiety   
 Basal ganglia 43 23.9  Healthy (SCARED < 23) 80 74.8
 Bifocal origins Aa 30 16.7  Anxiety (SCARED ≥ 23) 27 25.2
 Bifocal origins Ba 30 16.7 Adult depression   
 Dissemination 5 2.8  Healthy (SCL-90 sub-score < 2) 35 68.6
  22 12.2  Depression (SCL-90 sub-score ≥ 2) 16 31.4
    Adult anxiety   
     Healthy (SCL-90 sub-score < 2) 41 80.4
     Anxiety (SCL-90 sub-score ≥ 2) 10 19.6
  1. GCT, germ cell tumour; NGGCT, non-germinoma germ cell tumour; WBI, whole brain irradiation; CSI, craniospinal irradiation; CDI, children’s depression inventory; SCARED, screen for child anxiety related emotional disorders; SCL-90, symptom checklist 90 revised
  2. aBifocal origins A: pineal and suprasellar regions. Bifocal origins B: suprasellar region and basal ganglia regions