Table 4 Baseline moderate-severe symptoms or functional problems and changes at 12 months for the full cohort at both time points
Health-related quality of life domains | Symptoms and functional problems at baseline, n (%) (N = 90) | Changes from baseline to 12 months, n (%) (N = 50) | ||||
|---|---|---|---|---|---|---|
Mild or no symptoms | Moderate | Severe | No change | Deterioration | Improvement | |
EORTC-QLQ-C30 | ||||||
Global health status | 30 (33) | 41 (46) | 19 (21) | 30 (59) | 7 (14) | 13 (27) |
Physical functioning | 60 (70) | 20 (22) | 7 (8) | 37 (74) | 5 (10) | 8 (16) |
Role functioning | 36 (40) | 31 (34) | 23 (26) | 28 (56) | 8 (16) | 14 (28) |
Emotional functioning | 64 (71) | 23 (26) | 3 (3) | 34 (68) | 8 (16) | 8 (16) |
Cognitive functioning | 66 (74) | 20 (22) | 4 (4) | 36 (72) | 8 (16) | 6 (12) |
Social functioning | 57 (63) | 25 (28) | 8 (9) | 36 (72) | 3 (6) | 11 (22) |
Fatigue | 30 (34) | 40 (44) | 20 (22) | 28 (56) | 9 (18) | 13 (26) |
Nausea and vomiting | 79 (88) | 8 (9) | 3 (3) | 44 (88) | 2 (4) | 4 (8) |
Pain | 50 (56) | 28 (31) | 12 (13) | 35 (70) | 4 (8) | 11 (22) |
Dyspnea | 52 (57) | 30 (34) | 8 (9) | 38 (76) | 5 (10) | 7 (14) |
Insomnia | 45 (50) | 26 (29) | 19 (21) | 29 (58) | 9 (18) | 12 (24) |
Appetite loss | 55 (62) | 22 (24) | 13 (14) | 27 (54) | 8 (16) | 15 (30) |
Constipation | 71 (79) | 12 (13) | 7 (8) | 39 (78) | 6 (12) | 5 (10) |
Diarrhea | 60 (67) | 19 (21) | 11 (12) | 33 (66) | 9 (18) | 8 (16) |
Financial difficulties | 80 (89) | 8 (9) | 2 (2) | 43 (86) | 3 (6) | 4 (8) |
HADS | ||||||
Anxiety | 89 (99) | 1 (1) | NA | 44 (87) | 5 (11) | 1 (2) |
Depression | 89 (99) | 1 (1) | NA | 48 (96) | 1 (2) | 1 (2) |