Health-related quality of life in amyotrophic lateral sclerosis using EQ-5D-5L

Table 3 Multivariate logistic regression analysis of healthy utility scores and EQ-VAS scores for ALS patients

		Variables	Rating	P	OR value	Adjusted OR value	95% CI
All patients	Healthy utility score	ALSFRS-R groups	0 = ≥ 40; 1 = < 40	< 0.001	8.342	6.870	3.915, 12.054
		Depression	0 = no; 1 = yes	< 0.001	7.191	4.630	2.858, 7.501
		Anxiety	0 = no; 1 = yes	0.015	5.509	1.986	1.145, 3.442
	EQ-VAS score	Stages	0 = stage 1; 1 = stage 2; 2 = stage 3	0.042	1.879	1.353	1.011, 1.810
		ALSFRS-R groups	0 = ≥ 40; 1 = < 40	0.002	3.404	2.170	1.315, 3.582
		Depression	0 = no; 1 = yes	< 0.001	3.144	2.566	1.756, 3.748

VAS, visual analog scale; ALSFRS-R, Amyotrophic Lateral Sclerosis Functional Rating Scale– Revised; OR, odds ratio; CI, confidence interval

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