standard A, anchor-based method > ROC curve method > multiple linear regression models. The recommended MCID values of physical domain, psychological domain, social domain, common symptom and side-effects domain, the specific domain and the overall of the QLICP-ES were 7.8, 9.7, 4.7, 3.6, 4.3, 2.3 and 2.9, respectively. Conclusion Different methods have their own advantages and disadvantages, and also different definitions and standards can be adopted according to research purposes and methods. A lot of different MCID values were presented in this paper so that it can be easy and convenient to select by users."/>
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Table 2 The MCID of QLICP-ES (V2.0) determined by anchor-based method (nA = 102, nB = 165)

From: Exploration of the methods of establishing the minimum clinical important difference based on anchor and its application in the quality of life measurement scale QLICP-ES (V2.0) for esophageal cancer

Domain Items Standard A
\(\stackrel{-}{x}\pm s\)
Standard B
\(\stackrel{-}{x}\pm s\)
Standard A MCID Standard B MCID
Physical domain (PHD) 8 15.1 ± 14.8 19.3 ± 16.1 15.1 19.3
Psychological domain (PSD) 9 − 4.4 ± 11.8 − 4.2 ± 12.4 4.4 4.2
Social domain (SOD) 8 3.1 ± 10.2 4.8 ± 11.2 3.1 4.8
Common symptoms and side effect domain (SSD) 7 6.7 ± 10.7 7.7 ± 11.3 6.7 7.7
Core/general module (CGM) 32 4.8 ± 6.5 6.5 ± 7.3 4.8 6.5
Specific domain (SPD) 16 8.5 ± 8.3 9.5 ± 9.2 8.5 9.5
Total (TOT) 48 6.0 ± 6.0 7.5 ± 6.8 6.0 7.5