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Table 3 Meta-regression of weighted mean differences in health utilities between self- and proxy-reports

From: A comparison of self-reported and proxy-reported health utilities in children: a systematic review and meta-analysis

 

β

95% CI

P

Adjusted P †

Constant

0.047

(0.004,0.090)

0.034

 

Health condition*

 General population

Reference

   

 Infectious and parasitic diseases

0.000

(− 0.088, 0.088)

0.998

1.000

 Cancer

0.014

(− 0.049,0.077)

0.655

1.000

 Endocrine, nutritional and metabolic disorders

0.024

(− 0.024, 0.073)

0.330

0.997

 Mental and behavioral disorders

0.004

(− 0.044, 0.052)

0.876

1.000

 Nervous system disorders

0.054

(0.040, 0.148)

0.256

0.986

 Diseases of the ear

0.127

(0.046, 0.209)

0.002

0.024

 Circulatory system disorders

− 0.050

(− 0.181, 0.082)

0.459

1.000

 Respiratory system disorders

0.021

(− 0.054, 0.096)

0.583

1.000

 Musculoskeletal disorders

− 0.030

(− 0.086, 0.026)

0.288

0.994

 Genitourinary system disorders

0.098

(0.031, 0.166)

0.005

0.055

 Conditions originating in the perinatal period

− 0.010

(− 0.066, 0.045)

0.711

1.000

 Congenital malformations

− 0.020

(− 0.121, 0.082)

0.703

1.000

 Injury, poisoning and other consequences of external causes

− 0.127

(− 0.255, 0.002)

0.053

0.490

 Chronic illness

− 0.095

(− 0.170, − 0.020)

0.013

0.154

Valuation methods

 VAS

Reference

   

 SG

0.007

(− 0.040, 0.054)

0.767

1.000

 TTO

− 0.059

(− 0.127, 0.008)

0.083

0.658

 EQ-5D

− 0.110

(− 0.163, − 0.058)

 < 0.001

0.001

 EQ-5D-Y

− 0.045

(− 0.095, 0.006)

0.085

0.672

 HUI2

− 0.067

(− 0.111, − 0.024)

0.002

0.025

 HUI3

− 0.020

(− 0.052, 0.013)

0.228

0.967

 CHU-9D

− 0.041

(− 0.094, 0.012)

0.132

0.837

 QWB

− 0.041

(− 0.158, 0.076)

0.489

1.000

 PAHOM

− 0.104

(− 0.175, − 0.034)

0.004

0.048

Proxy types

 Proxy assessment by parents

Reference

   

 Proxy assessment by clinicians

0.083

(0.016, 0.151)

0.016

0.185

 Proxy assessment by caregivers

− 0.061

(− 0.114, − 0.008)

0.025

0.274

  1. VAS visual analogue scale, SG standard gamble, TTO time trade-off, HUI health utility index, EQ-5D-Y EuroQol 5-dimension youth version, CHU9D child health utility 9-dimension, QWB quality of well-being scale, PAHOM pediatric asthma health outcome measure
  2. *Health conditions were reported based on ICD-10 categories
  3. †P values were adjusted by Monte Carlo permutation test with 1000 iterations
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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