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Table 5 Clinical characteristics associated with EQ-5D and EQ-VAS score of patients with HIV/AIDS, TASH, Ethiopia, 2019 (n = 511)

From: Health-related quality of life of patients with HIV/AIDS at a tertiary care teaching hospital in Ethiopia

Patient character

EQ-5D

EQ-VAS

Median [IQR]

Mean rank

p value

Median [IQR]

Mean rank

p value

CD4 cells/mm3

 > 500

1 [0.94–1]

339

 < 0.001*

90 [82–99.75]

346

 < 0.001*

[350–500]

0.94 [0.88–1]

258

85 [70.25–90]

268

[200–350]

0.94 [0.86–0.97]

232

77.5 [65–85]

213

[100–200]

0.88 [0.76–0.95]

172

70 [60–85]

184

 < 100

0.88 [0.66–0.96]

184

60 [50–83.75]

166

WHO clinical stage at diagnosis

I

0.94 [0.85–0.97]

233

0.06

85 [72.5–90]

264

0.08

II

0.96 [0.87–1]

261

85 [70–95]

266

III

0.96 [0.89–1]

273

82.5 [70–95]

265

IV

0.94 [0.86–1]

235

80 [65–90]

229

Viral load

 < 50 copies/ml

0.95 [0.88–1]

263

0.005*

85 [70–95]

267

 < 0.001*

51–1000 copies/ml

0.94 [0.88–1]

257

82.5 [70–95]

260

 > 1000 copies/ml

0.88 [0.7–0.98]

196

70 [60–80]

169

Type of medicine

AZT/3TC/EFV

0.97 [0.94–1]

309

0.004*

82.5 [70–91.75]

286

0.002*

AZT/3TC/NVP

0.96 [0.88–1]

271

85 [71.25–90]

278

TDF/3TC/EFV

0.96 [0.88–1]

264

85 [70–95]

268

TDF/3TC/NVP

0.94 [0.89–1]

269

85 [75–95]

280

ABC + 3TC + EFV

0.88 [0.82–0.96]

189

70 [60–80]

192

TDF + 3TC + ATV/r

0.82 [0.77–0.97]

253

70 [51.25–85]

238

Others**

0.94 [0.86–1]

205

80 [65–90]

193

 

Number of medicine

1

0.96 [0.9–1]

289

 < 0.001*

90 [70–95]

289

 < 0.001*

2

0.94 [0.85–0.97]

240

80 [70–90]

246

3

0.94 [0.86–1]

239

80 [65–90]

240

4

0.91 [0.83–0.97]

225

75 [60–90]

214

 > 4

0.89 [0.76–0.97]

179

70 [50–80]

144

Duration of treatment

 

 < 1 year

0.96 [0.94–0.96]

49

0.08

85 [72.5–90]

51

0.12

1–5 years

0.92 [0.86–0.97]

50

80 [66.25–90]

45

 > 5 years

0.96 [0.88–1]

51

82.5 [70–95]

55

Adherence

Good

0.95 [0.88–1]

259

0.14

80 [70–90]

259

0.08

Fair

0.93 [0.84–1]

225

72.5 [56–93.75]

223

Poor

0.89 [0.7–1]

209

70 [60–90]

201

History of treatment failure

Yes

0.92 [0.83–0.97]

210

0.001*

70 [60–85]

195

 < 0.001*

No

0.96 [0.88–1]

266

85 [70–95]

270

Comorbidities

No

0.96 [0.88–1]

216

0.001*

85 [70–95]

213

 < 0.001*

OIs

0.92 [0.84–0.97]

273

70 [55–90]

274

Non-OIs

0.92 [0.8–0.97]

336

80 [65–90]

237

  1. *Significant value
  2. **Others: ABC + 3TC + NVP, TDF + 3TC + LPV/r and AZT + 3TC + LPV/r; NVP: Nevirapine; ABC: Abacavir; OIs: Opportunistic infect