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Table 2 Relationships between sociodemographic and clinical characteristics and quality of life of patients and FCs

From: Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: a cross-sectional study

CharacteristicTotal FACT-Leu score (Patients)SF-36 PCS score (FCs)SF-36 MCS score (FCs)
Mean ± SDStatisticpMean ± SDStatisticpMean ± SDStatisticp
Sex −2.03 (t)0.044 −0.004 (t)0.997 −3.573 (t)0.004
 Male74.65 ± 16.41  64.67 ± 14.76 48.92 ± 13.86 
 Female79.39 ± 16.19  64.68 ± 16.09 55.62 ± 12.40 
Age (years) 2.259 (F)0.107 3.798 (F)0.024 2.587 (F)0.078
  < 4575.38 ± 16.11  66.88 ± 15.49 54.16 ± 14.33 
 45–5981.39 ± 16.20  60.52 ± 14.83 49.59 ± 11.54 
 60–7476.33 ± 18.70  65.75 ± 13.36 50.72 ± 11.33 
Marital status −0.793 (t)0.429 3.758 (t)< 0.001 4.626 (t)< 0.001
 Married77.38 ± 16.31  63.18 ± 15.42 50.93 ± 12.94 
 Unmarried75.31 ± 16.81  75.42 ± 10.80 63.86 ± 11.98 
Educational level 0.132 (F)0.876 9.299 (F)0.000 1.578 (F)0.209
 Primary school or below75.75 ± 12.86  55.96 ± 14.81 51.25 ± 12.47 
 Middle or high school77.29 ± 18.21  64.85 ± 14.85 51.57 ± 13.16 
 University or higher76.37 ± 14.38  70.10 ± 14.78 55.38 ± 14.64 
Religious belief 0.039 (t)0.969 0.332 (t)0.740 −0.463 (t)0.644
 Yes76.75 ± 16.12  64.32 ± 17.16 52.95 ± 13.48 
 No76.85 ± 16.79  65.05 ± 13.51 52.05 ± 13.55 
Employment −3.234 (t)0.001 2.722 (t)0.007 0.893 (t)0.373
 Employed65.80 ± 16.66  68.97 ± 14.66  53.76 ± 14.70  
 Unemployed78.05 ± 15.99  64.64 ± 15.44 51.92 ± 12.89 
Type of leukemia −0.948 (t)0.344     
 AML77.68 ± 17.14      
 ALL75.39 ± 15.24      
Treatment −2.030 (t)0.044     
 Chemotherapy75.66 ± 15.62      
 Non-chemotherapy81.70 ± 19.03      
Undergoing initial treatment 0.680 (t)0.498    
 Yes77.66 ± 15.43      
 No76.06 ± 17.30      
Relationship to patient 1.126 (F)0.346 4.644 (F)0.001 4.621 (F)0.001
 Spouse78.17 ± 13.88  63.33 ± 15.13 51.66 ± 13.04 
 Parent73.06 ± 18.39  60.61 ± 15.67 49.26 ± 13.61 
 Child79.02 ± 19.30  67.99 ± 14.37 53.87 ± 13.75 
 Sibling72.14 ± 20.68  74.29 ± 15.78 62.78 ± 8.25 
 Other76.57 ± 6.58  81.79 ± 2.27 68.23 ± 1.66 
Understanding of the disease   0.726 (F)0.458 1.640 (F)0.197
 Incomplete   59.50 ± 16.29 42.49 ± 7.42 
 Partial   63.73 ± 16.11 52.11 ± 14.77 
 Complete   65.82 ± 14.80 53.39 ± 12.29 
  1. ALL acute lymphoblastic leukemia, AML acute myelogenous leukemia, SD standard deviation, PCS physical component summary, MCS mental component summary, FC family caregiver, FACT-Leu Functional Assessment of Cancer Therapy-Leukemia, SF-36 36-item Short-Form Health Survey