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Table 2 Relationships between sociodemographic and clinical characteristics and quality of life of patients and FCs

From: Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: a cross-sectional study

Characteristic

Total FACT-Leu score (Patients)

SF-36 PCS score (FCs)

SF-36 MCS score (FCs)

Mean ± SD

Statistic

p

Mean ± SD

Statistic

p

Mean ± SD

Statistic

p

Sex

 

−2.03 (t)

0.044

 

−0.004 (t)

0.997

 

−3.573 (t)

0.004

 Male

74.65 ± 16.41

  

64.67 ± 14.76

 

48.92 ± 13.86

 

 Female

79.39 ± 16.19

  

64.68 ± 16.09

 

55.62 ± 12.40

 

Age (years)

 

2.259 (F)

0.107

 

3.798 (F)

0.024

 

2.587 (F)

0.078

  < 45

75.38 ± 16.11

  

66.88 ± 15.49

 

54.16 ± 14.33

 

 45–59

81.39 ± 16.20

  

60.52 ± 14.83

 

49.59 ± 11.54

 

 60–74

76.33 ± 18.70

  

65.75 ± 13.36

 

50.72 ± 11.33

 

Marital status

 

−0.793 (t)

0.429

 

3.758 (t)

< 0.001

 

4.626 (t)

< 0.001

 Married

77.38 ± 16.31

  

63.18 ± 15.42

 

50.93 ± 12.94

 

 Unmarried

75.31 ± 16.81

  

75.42 ± 10.80

 

63.86 ± 11.98

 

Educational level

 

0.132 (F)

0.876

 

9.299 (F)

0.000

 

1.578 (F)

0.209

 Primary school or below

75.75 ± 12.86

  

55.96 ± 14.81

 

51.25 ± 12.47

 

 Middle or high school

77.29 ± 18.21

  

64.85 ± 14.85

 

51.57 ± 13.16

 

 University or higher

76.37 ± 14.38

  

70.10 ± 14.78

 

55.38 ± 14.64

 

Religious belief

 

0.039 (t)

0.969

 

0.332 (t)

0.740

 

−0.463 (t)

0.644

 Yes

76.75 ± 16.12

  

64.32 ± 17.16

 

52.95 ± 13.48

 

 No

76.85 ± 16.79

  

65.05 ± 13.51

 

52.05 ± 13.55

 

Employment

 

−3.234 (t)

0.001

 

2.722 (t)

0.007

 

0.893 (t)

0.373

 Employed

65.80 ± 16.66

  

68.97 ± 14.66

  

53.76 ± 14.70

  

 Unemployed

78.05 ± 15.99

  

64.64 ± 15.44

 

51.92 ± 12.89

 

Type of leukemia

 

−0.948 (t)

0.344

     

 AML

77.68 ± 17.14

      

 ALL

75.39 ± 15.24

      

Treatment

 

−2.030 (t)

0.044

     

 Chemotherapy

75.66 ± 15.62

      

 Non-chemotherapy

81.70 ± 19.03

      

Undergoing initial treatment

 

0.680 (t)

0.498

    

 Yes

77.66 ± 15.43

      

 No

76.06 ± 17.30

      

Relationship to patient

 

1.126 (F)

0.346

 

4.644 (F)

0.001

 

4.621 (F)

0.001

 Spouse

78.17 ± 13.88

  

63.33 ± 15.13

 

51.66 ± 13.04

 

 Parent

73.06 ± 18.39

  

60.61 ± 15.67

 

49.26 ± 13.61

 

 Child

79.02 ± 19.30

  

67.99 ± 14.37

 

53.87 ± 13.75

 

 Sibling

72.14 ± 20.68

  

74.29 ± 15.78

 

62.78 ± 8.25

 

 Other

76.57 ± 6.58

  

81.79 ± 2.27

 

68.23 ± 1.66

 

Understanding of the disease

   

0.726 (F)

0.458

 

1.640 (F)

0.197

 Incomplete

   

59.50 ± 16.29

 

42.49 ± 7.42

 

 Partial

   

63.73 ± 16.11

 

52.11 ± 14.77

 

 Complete

   

65.82 ± 14.80

 

53.39 ± 12.29

 
  1. ALL acute lymphoblastic leukemia, AML acute myelogenous leukemia, SD standard deviation, PCS physical component summary, MCS mental component summary, FC family caregiver, FACT-Leu Functional Assessment of Cancer Therapy-Leukemia, SF-36 36-item Short-Form Health Survey