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Table 1 Patients sociodemographic and clinical characteristics

From: EQ-5D-3L health state utility values in transfusion-dependent thalassemia patients in Malaysia: a cross-sectional assessment

Characteristics Total (N = 585)
Age in years, mean (SD) 17.2 (5.4)
Age at first transfusion in years, mean (SD) 5.4 (7.9)
Number of years receiving blood transfusion, mean (SD) 11.3 (8.9)
Source of survey (%)  
 Self-reported 332 (56.8)
 Proxy-reported 253 (43.2)
Gender (%)  
 Male 259 (44.3)
 Female 326 (55.7)
Ethnicity (%)  
 Malay 403 (68.9)
 Chinese 94 (16.1)
 Kadazan-Dusun 58 (9.9)
 Others 30 (5.1)
Education level of proxy’s who completed proxy-report, n = 251 (%)  
 No formal education 10 (4.0)
 Primary or secondary education 180 (71.7)
 Tertiary education 61 (24.3)
Education level of patients who completed self-report, n = 331 (%)  
 No formal education 3 (0.9)
 Primary or secondary education 207 (62.5)
 Tertiary education 121 (36.6)
Presence of iron overload (IOL) complication (%)  
 No complication 331 (56.6)
 One complication 164 (28.0)
 Two complications 66 (11.3)
 Three or more complications 24 (4.1)
 Cardiac disease 39 (15.3*)
 Diabetes 20 (7.9*)
 Hypothyroid 25 (9.8*)
 Hypogonadism 90 (35.4*)
 Hypoparathyroidism 52 (20.5*)
 Liver disease 124 (48.8*)
Iron chelation therapy (%)  
 Desferrioxamine (subcutaneous (SC) drug) 68 (11.6)
 Deferasirox (oral (PO) drug) 245 (41.9)
 Deferiprone (oral (PO) drug) 73 (12.5)
 Desferrioxamine + Deferiprone (SC + PO drug) 154 (26.3)
 Desferrioxamine + Deferasirox (SC + PO drug) 32 (5.8)
 Deferiprone + Deferasirox (both oral drugs) 13 (2.2)
Number of iron chelating agents (%)  
 Monotherapy 386 (66.0)
 Dual therapy 199 (34.0)
Route of iron chelating administration (%)  
 Subcutaneous 68 (11.6)
 Oral 331 (56.6)
 Subcutaneous + Oral 186 (31.8)
History of serious adverse event with iron chelation therapy (%)  
 Yes 76 (13.0)
 No 509 (87.0)
  1. N, number; SD, standard deviation; IOL, iron overload complication; SC, subcutaneous; PO, oral
  2. *Percentage calculated based on the total number of people who has complication