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Table 4 Health-related quality of life as measured by the FACT-B scores by patient group

From: Health-related quality of life and work productivity in UK patients with HER2-positive breast cancer: a cross-sectional study evaluating the relationships between disease and treatment stage

  Group 1 Group 2 Group 3 Between-group differences
Fisher p value
FACT-B subscales (mean, SD)
 Physical wellbeing 20.57 (5.93) (n = 86) 22.63 (5.08) (n = 107) 18.81 (6.89) (n = 101) < 0.001
 Social wellbeing 23.62 (4.88) (n = 86) 22.26 (5.23) (n = 108) 20.65 (6.34) (n = 100) 0.001
 Emotional wellbeing 18.13 (4.87) (n = 87) 17.68 (4.87) (n = 107) 15.19 (5.99) (n = 100) < 0.001
 Functional wellbeing 18.69 (6.32) (n = 88) 20.76 (5.52) (n = 108) 16.43 (7.30) (n = 101) < 0.001
 Breast cancer-specific 22.01 (7.00) (n = 86) 22.38 (7.68) (n = 108) 21.37 (6.96) (n = 101) 0.602
FACT-B summary scores (mean, SD)
 FACT-Ga 80.89 (17.69) (n = 85) 83.19 (16.80) (n = 106) 71.07 (22.42) (n = 99) < 0.001
 FACT-B total 102.93 (23.41) (n = 85) 105.58 (23.00) (n = 106) 92.24 (27.38) (n = 99)  < 0.001
 Trial outcome indexb 61.19 (16.95) (n = 86) 65.74 (16.05) (n = 107) 56.61 (18.14) (n = 101) 0.001
  1. Higher scores reflect higher levels of HRQoL. n, numbers shown where data were not available for all patients
  2. aFACT-G: Functional Assessment of Cancer Therapy-General; constitutes the non-tumour specific core of the FACT-B subscale [18]
  3. bTrial outcome index calculated from the sum of the physical wellbeing, functional wellbeing, and additional concerns subscales of the FACT-B [18]