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Table 11 Assessment of responsiveness of the EQ-5D-3L and the EQ-5D-5L measures to changes in the Barthel Index, for the subgroup in Switzerland

From: Measurement properties of EQ-5D-3L and EQ-5D-5L in recording self-reported health status in older patients with substantial multimorbidity and polypharmacy

 

EQ-5D-3L at 6 months (mean)

EQ-5D-3L at 12 months (mean)

Difference between 12 and 6 months EQ-5D-3L (95% CI)

Effect size (Cohen’s D)a

n

% reporting 3L score increase

Barthel Index

 Improved

0.41

0.79

0.38 (0.04 to 0.71)

1.63*

4

100

 No change

0.93

0.89

− 0.03 (− 0.10 to 0.02)

− 0.23

39

15

 Worsened

0.84

0.70

− 0.13 (− 0.30 to 0.02)

− 0.54

12

17

 

EQ-5D-5L at 6 months (mean)

EQ-5D-5L at 12 months (mean)

Difference between 12 and 6 months EQ-5D-5L (95% CI)

Effect size (Cohen’s D)

n

% reporting 5L score increase

Barthel Index

 Improved

0.40

0.73

0.32 (0.01 to 0.63)

1.49

4

100

 No change

0.91

0.90

− 0.01 (− 0.05 to 0.02)

− 0.11

39

15

 Worsened

0.78

0.71

− 0.06 (− 0.20 to 0.07)

− 0.28

12

33

  1. aCohen’s D effect sizes of between 0.2 and 0.5 are considered small, 0.5 and 0.8 moderate and > 0.8 large
  2. *p < 0.05