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Table 6 Results of multivariable regression analyses in emotional QoL in MG-QOL15r

From: Gender differences in quality of life among patients with myasthenia gravis in China

Emotional QoL

Model 1

Model 2

Model 3

β (95% CI)

P-value

β (95% CI)

P-value

β (95% CI)

P-value

Socio-demographic variables

 Age

0.31 (0.16 to 0.45)

< 0.001

0.29 (0.14 to 0.43)

< 0.001

0.29 (0.14 to 0.44)

< 0.001

 Education

1.43 (− 0.56 to 3.43)

0.159

1.41 (− 0.58 to 3.41)

0.164

1.38 (− 0.61 to 3.38)

0.175

 Unemployment

−4.79 (− 8.60 to − 0.98)

< 0.05

− 4.47 (− 8.32 to − 0.63)

< 0.05

− 4.41 (− 8.26 to − 0.57)

< 0.05

 Annual household income

0.00 (0.00 to 0.00)

< 0.05

0.00 (0.00 to 0.00)

< 0.05

0.00 (0.00 to 0.00)

< 0.05

Diagnosis and treatment history

 Thymectomy (0 = no; 1 = yes)

−1.45 (− 4.97 to 2.07)

0.420

− 1.49 (−5.01 to 2.02)

0.405

− 1.56 (− 5.07 to 1.96)

0.386

 MG exacerbations (0 = no; 1 = yes)

−10.08 (− 14.08 to − 6.07)

< 0.001

− 10.08 (− 14.08 to − 6.08)

< 0.001

− 10.08 (− 14.08 to − 6.08)

< 0.001

 Prednisone treatment (0 = never had prednisone)

      

 Current prednisone

−3.78 (− 8.09 to 0.52)

0.085

− 3.84 (− 8.14 to 0.47)

0.081

− 3.73 (− 8.04 to 0.57)

0.089

 Past prednisone

−3.58 (− 8.71 to 1.55)

0.171

− 3.56 (− 8.69 to 1.58)

0.174

− 3.38 (− 8.61 to 1.65)

0.183

Number of comorbid conditions

−0.46 (− 1.44 to 0.53)

0.362

− 0.50 (− 1.48 to 0.49)

0.323

0.10 (−1.23 to 1.43)

0.885

Social support and Active lifestyle

 Tangible support

−0.01 (− 0.11 to 0.09)

0.795

− 0.02 (− 0.12 to 0.08)

0.730

−0.02 (− 0.12 to 0.08)

0.740

 Affectionate support

0.18 (0.01 to 0.35)

< 0.05

0.19 (0.02 to 0.36)

< 0.05

0.19 (0.02 to 0.36)

< 0.05

 Positive social interaction

0.07 (−0.09 to 0.22)

0.384

0.06 (−0.10 to 0.21)

0.467

0.06 (−0.10 to 0.21)

0.471

 Emotional/information support

0.00 (−0.13 to 0.13)

0.966

0.01 (−0.12 to 0.14)

0.923

0.00 (−0.13 to 0.13)

0.972

 Active lifestyle

0.25 (0.09 to 0.41)

< 0.01

0.25 (0.09 to 0.40)

< 0.01

0.25 (0.09 to 0.41)

< 0.01

MG-ADL

−3.32 (−3.80 to −2.85)

< 0.001

− 3.31 (− 3.79 to − 2.84)

< 0.001

−3.29 (− 3.77 to − 2.82)

< 0.001

Gender (0 = male; 1 = female)

  

− 2.33 (− 6.20 to 1.55)

0.238

−1.03 (− 5.37 to 3.30)

0.640

Gender × Comorbiditiesa

    

−1.24 (−3.10 to 0.63)

0.192

Adjusted R-squared

0.4497

0.45

0.4505

  1. Abbreviation: CI confidence interval
  2. aNumber of comorbid conditions