From: Gender differences in quality of life among patients with myasthenia gravis in China
Emotional QoL | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | |
Socio-demographic variables | ||||||
 Age | 0.31 (0.16 to 0.45) | < 0.001 | 0.29 (0.14 to 0.43) | < 0.001 | 0.29 (0.14 to 0.44) | < 0.001 |
 Education | 1.43 (− 0.56 to 3.43) | 0.159 | 1.41 (− 0.58 to 3.41) | 0.164 | 1.38 (− 0.61 to 3.38) | 0.175 |
 Unemployment | −4.79 (− 8.60 to − 0.98) | < 0.05 | − 4.47 (− 8.32 to − 0.63) | < 0.05 | − 4.41 (− 8.26 to − 0.57) | < 0.05 |
 Annual household income | 0.00 (0.00 to 0.00) | < 0.05 | 0.00 (0.00 to 0.00) | < 0.05 | 0.00 (0.00 to 0.00) | < 0.05 |
Diagnosis and treatment history | ||||||
 Thymectomy (0 = no; 1 = yes) | −1.45 (− 4.97 to 2.07) | 0.420 | − 1.49 (−5.01 to 2.02) | 0.405 | − 1.56 (− 5.07 to 1.96) | 0.386 |
 MG exacerbations (0 = no; 1 = yes) | −10.08 (− 14.08 to − 6.07) | < 0.001 | − 10.08 (− 14.08 to − 6.08) | < 0.001 | − 10.08 (− 14.08 to − 6.08) | < 0.001 |
 Prednisone treatment (0 = never had prednisone) |  |  |  |  |  |  |
 Current prednisone | −3.78 (− 8.09 to 0.52) | 0.085 | − 3.84 (− 8.14 to 0.47) | 0.081 | − 3.73 (− 8.04 to 0.57) | 0.089 |
 Past prednisone | −3.58 (− 8.71 to 1.55) | 0.171 | − 3.56 (− 8.69 to 1.58) | 0.174 | − 3.38 (− 8.61 to 1.65) | 0.183 |
Number of comorbid conditions | −0.46 (− 1.44 to 0.53) | 0.362 | − 0.50 (− 1.48 to 0.49) | 0.323 | 0.10 (−1.23 to 1.43) | 0.885 |
Social support and Active lifestyle | ||||||
 Tangible support | −0.01 (− 0.11 to 0.09) | 0.795 | − 0.02 (− 0.12 to 0.08) | 0.730 | −0.02 (− 0.12 to 0.08) | 0.740 |
 Affectionate support | 0.18 (0.01 to 0.35) | < 0.05 | 0.19 (0.02 to 0.36) | < 0.05 | 0.19 (0.02 to 0.36) | < 0.05 |
 Positive social interaction | 0.07 (−0.09 to 0.22) | 0.384 | 0.06 (−0.10 to 0.21) | 0.467 | 0.06 (−0.10 to 0.21) | 0.471 |
 Emotional/information support | 0.00 (−0.13 to 0.13) | 0.966 | 0.01 (−0.12 to 0.14) | 0.923 | 0.00 (−0.13 to 0.13) | 0.972 |
 Active lifestyle | 0.25 (0.09 to 0.41) | < 0.01 | 0.25 (0.09 to 0.40) | < 0.01 | 0.25 (0.09 to 0.41) | < 0.01 |
MG-ADL | −3.32 (−3.80 to −2.85) | < 0.001 | − 3.31 (− 3.79 to − 2.84) | < 0.001 | −3.29 (− 3.77 to − 2.82) | < 0.001 |
Gender (0 = male; 1 = female) |  |  | − 2.33 (− 6.20 to 1.55) | 0.238 | −1.03 (− 5.37 to 3.30) | 0.640 |
Gender × Comorbiditiesa |  |  |  |  | −1.24 (−3.10 to 0.63) | 0.192 |
Adjusted R-squared | 0.4497 | 0.45 | 0.4505 |