From: Gender differences in quality of life among patients with myasthenia gravis in China
Social QoL | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
β (95% CI) | P-Value | β (95% CI) | P-Value | β (95% CI) | P-Value | |
Socio-demographic variables | ||||||
 Age | 0.21 (0.07 to 0.36) | < 0.01 | 0.22 (0.07 to 0.37) | < 0.01 | 0.23 (0.08 to 0.38) | < 0.01 |
 Education | 1.17 (− 0.86 to 3.21) | 0.258 | 1.18 (− 0.86 to 3.22) | 0.256 | 1.13 (− 0.91 to 3.16) | 0.277 |
 Unemployment | − 5.68 (− 9.57 to − 1.79) | < 0.05 | −5.78 (− 9.70 to − 1.85) | < 0.01 | −5.68 (− 9.60 to − 1.76) | < 0.01 |
 Annual household income | 0.00 (0.00 to 0.00) | 0.070 | 0.00 (0.00 to 0.00) | 0.067 | 0.00 (0.00 to 0.00) | 0.058 |
Diagnosis and treatment history | ||||||
 Thymectomy (0 = no; 1 = yes) | −0.788 (−4.38 to 2.80) | 0.667 | −0.77 (− 4.37 to 2.82) | 0.672 | − 0.87 (− 4.46 to 2.72) | 0.633 |
 MG exacerbations (0 = no; 1 = yes) | −9.23 (− 13.31 to −5.15) | < 0.001 | − 9.23 (− 13.31 to − 5.14) | < 0.001 | − 9.22 (− 13.30 to − 5.15) | < 0.001 |
 Prednisone treatment (0 = never had prednisone) |  |  |  |  |  |  |
 Current prednisone | −3.79 (− 8.18 to 0.61) | 0.091 | − 3.77 (− 8.16 to 0.62) | 0.093 | − 3.61 (− 8.00 to 0.78) | 0.107 |
 Past prednisone | −0.13 (− 5.37 to 5.10) | 0.960 | −0.14 (− 5.38 to 5.10) | 0.958 | − 0.022 (− 5.25 to 5.21) | 0.993 |
Number of comorbid conditions | − 0.31 (− 1.31 to 0.70) | 0.550 | − 0.29 (− 1.30 to 0.71) | 0.566 | 0.65 (− 0.71 to 2.01) | 0.347 |
Social support and Active lifestyle | ||||||
 Tangible support | − 0.13 (− 0.23 to − 0.03) | < 0.05 | − 0.13 (− 0.23 to − 0.03) | < 0.05 | −0.13 (− 0.23 to − 0.03) | < 0.05 |
 Affectionate support | 0.13 (− 0.04 to 0.30) | 0.146 | 0.12 (− 0.05 to 0.30) | 0.159 | 0.13 (− 0.04 to 0.30) | 0.136 |
 Positive social interaction | 0.14 (0.02 to 0.30) | 0.082 | 0.14 (0.02 to 0.30) | 0.077 | 0.14 (−0.02 to 0.30) | 0.078 |
 Emotional/information support | −0.04 (− 0.17 to 0.10) | 0.599 | − 0.04 (− 0.17 to 0.09) | 0.575 | −0.04 (− 0.18 to 0.09) | 0.511 |
 Active lifestyle | 0.33 (0.16 to 0.49) | < 0.001 | 0.33 (0.17 to 0.49) | < 0.001 | 0.33 (0.17 to 0.49) | < 0.001 |
MG-ADL | −3.61 (− 4.09 to − 3.12) | < 0.001 | −3.61 (− 4.10 to − 3.13) | < 0.001 | −3.58 (− 4.07 to − 3.10) | < 0.001 |
Gender (0 = male; 1 = female) |  |  | 0.67 (− 3.28 to 4.63) | 0.738 | 2.73 (−1.69 to 7.15) | 0.226 |
Gender × Comorbiditiesa |  |  |  |  | −1.97 (−3.87 to −0.07) | < 0.05 |
Adjusted R-squared | 0.4509 | 0.4503 | 0.4526 |