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Table 5 Results of multivariable regression analyses in social QoL in MG-QOL15r

From: Gender differences in quality of life among patients with myasthenia gravis in China

Social QoL

Model 1

Model 2

Model 3

β (95% CI)

P-Value

β (95% CI)

P-Value

β (95% CI)

P-Value

Socio-demographic variables

 Age

0.21 (0.07 to 0.36)

< 0.01

0.22 (0.07 to 0.37)

< 0.01

0.23 (0.08 to 0.38)

< 0.01

 Education

1.17 (− 0.86 to 3.21)

0.258

1.18 (− 0.86 to 3.22)

0.256

1.13 (− 0.91 to 3.16)

0.277

 Unemployment

− 5.68 (− 9.57 to − 1.79)

< 0.05

−5.78 (− 9.70 to − 1.85)

< 0.01

−5.68 (− 9.60 to − 1.76)

< 0.01

 Annual household income

0.00 (0.00 to 0.00)

0.070

0.00 (0.00 to 0.00)

0.067

0.00 (0.00 to 0.00)

0.058

Diagnosis and treatment history

 Thymectomy (0 = no; 1 = yes)

−0.788 (−4.38 to 2.80)

0.667

−0.77 (− 4.37 to 2.82)

0.672

− 0.87 (− 4.46 to 2.72)

0.633

 MG exacerbations (0 = no; 1 = yes)

−9.23 (− 13.31 to −5.15)

< 0.001

− 9.23 (− 13.31 to − 5.14)

< 0.001

− 9.22 (− 13.30 to − 5.15)

< 0.001

 Prednisone treatment (0 = never had prednisone)

      

 Current prednisone

−3.79 (− 8.18 to 0.61)

0.091

− 3.77 (− 8.16 to 0.62)

0.093

− 3.61 (− 8.00 to 0.78)

0.107

 Past prednisone

−0.13 (− 5.37 to 5.10)

0.960

−0.14 (− 5.38 to 5.10)

0.958

− 0.022 (− 5.25 to 5.21)

0.993

Number of comorbid conditions

− 0.31 (− 1.31 to 0.70)

0.550

− 0.29 (− 1.30 to 0.71)

0.566

0.65 (− 0.71 to 2.01)

0.347

Social support and Active lifestyle

 Tangible support

− 0.13 (− 0.23 to − 0.03)

< 0.05

− 0.13 (− 0.23 to − 0.03)

< 0.05

−0.13 (− 0.23 to − 0.03)

< 0.05

 Affectionate support

0.13 (− 0.04 to 0.30)

0.146

0.12 (− 0.05 to 0.30)

0.159

0.13 (− 0.04 to 0.30)

0.136

 Positive social interaction

0.14 (0.02 to 0.30)

0.082

0.14 (0.02 to 0.30)

0.077

0.14 (−0.02 to 0.30)

0.078

 Emotional/information support

−0.04 (− 0.17 to 0.10)

0.599

− 0.04 (− 0.17 to 0.09)

0.575

−0.04 (− 0.18 to 0.09)

0.511

 Active lifestyle

0.33 (0.16 to 0.49)

< 0.001

0.33 (0.17 to 0.49)

< 0.001

0.33 (0.17 to 0.49)

< 0.001

MG-ADL

−3.61 (− 4.09 to − 3.12)

< 0.001

−3.61 (− 4.10 to − 3.13)

< 0.001

−3.58 (− 4.07 to − 3.10)

< 0.001

Gender (0 = male; 1 = female)

  

0.67 (− 3.28 to 4.63)

0.738

2.73 (−1.69 to 7.15)

0.226

Gender × Comorbiditiesa

    

−1.97 (−3.87 to −0.07)

< 0.05

Adjusted R-squared

0.4509

0.4503

0.4526

  1. Abbreviation: CI confidence interval
  2. aNumber of comorbid conditions