Psychometric properties of the Japanese version of the Kansas City Cardiomyopathy Questionnaire in Japanese patients with chronic heart failure

Table 7 One-month change in KCCQ scores among patients with improved health states

KCCQ	N	Scores (mean ± SD)			Effect size	P value^b
KCCQ	N	Baseline	After one month of treatment^a	Change in scores	Effect size	P value^b
Domains
Physical limitations	35^c	66.4 ± 27.6	83.6 ± 18.2	17.2 ± 24.2	0.62	< 0.001
Symptom frequency	44	55.1 ± 31.6	82.0 ± 16.9	26.9 ± 30.2	0.85	< 0.001
Symptom severity	44	69.3 ± 25.5	87.5 ± 14.5	18.2 ± 24.4	0.71	< 0.001
Symptom stability	44	61.9 ± 33.4	69.9 ± 21.3	8.0 ± 42.4	0.24	0.220
Self-efficacy	44	66.5 ± 21.9	74.1 ± 23.9	7.7 ± 16.7	0.35	0.004
Social limitations	30^d	60.8 ± 31.4	81.2 ± 20.9	20.5 ± 28.4	0.65	< 0.001
Quality of life	44	47.3 ± 26.0	68.0 ± 19.3	20.6 ± 26.4	0.79	< 0.001
Summary scores
Total symptom score	44	62.2 ± 27.3	84.8 ± 15.0	22.5 ± 25.7	0.82	< 0.001
Clinical summary score	44	62.0 ± 25.7	83.7 ± 13.9	21.7 ± 21.3	0.85	< 0.001
Overall summary score	44	56.4 ± 25.3	78.5 ± 15.3	22.2 ± 20.7	0.88	< 0.001

Responsiveness was analyzed using data of 44 patients who showed improvement in their health state, which was defined as improvement in at least one EQ-5D dimension by ≥1 point without worsening in any EQ-5D dimension
^aFor the assessment of this timepoint, the KCCQ scores at week 4 for the SOCRATES studies and at day 30 for the ARTS-HF Japan study were used
^bDifferences in scores between baseline and the second assessment were tested using a paired t-test with equal variances assumed
^cData of 35 patients were analyzed due to responses coded as missing data in question 1 (6 items)
^dData of 30 patients were analyzed due to responses coded as missing data in question 15 (4 items)
Effect sizes: 0.2 = small; 0.5 = medium; 0.8 = large
KCCQ Kansas City Cardiomyopathy Questionnaire; SD standard deviation

ISSN: 1477-7525