Table 3 Quality of life scores before and 6 months after switch from IV or IM HBIG to SC HBIG
Domain | N | Baseline | End of study | P value* | Effect size |
|---|---|---|---|---|---|
ITaLi-Q | |||||
Side effects | 83 | 27.9 ± 27.5 | 5.5 ± 10.6 | < 0.0001 | 0.81 |
Side effects impact | 82 | 12.6 ± 19.0 | 2.3 ± 6.7 | < 0.0001 | 0.54 |
Negative feelings | 81 | 19.8 ± 25.5 | 5.7 ± 10.7 | < 0.0001 | 0.55 |
Positive feelings | 81 | 86.3 ± 18.3 | 87.0 ± 22.5 | 0.36 | 0.08 |
Flexibility | 79 | 31.8 ± 25.8 | 17.0 ± 14.9 | < 0.0001 | 0.57 |
Support | 75 | 52.3 ± 36.7 | 32.0 ± 27.6 | < 0.0001 | 0.55 |
Need for support | 80 | 38.7 ± 42.1 | 7.7 ± 19.0 | < 0.0001 | 0.74 |
Satisfaction | 80 | 59.6 ± 22.0 | 84.1 ± 17.1 | < 0.0001 | 1.11 |
SF-36 | |||||
Physical functioning | 85 | 76.2 ± 22.8 | 78.2 ± 24.0 | 0.05 | 0.09 |
Role physical | 81 | 64.8 ± 41.0 | 75.0 ± 39.7 | 0.03 | 0.25 |
Pain | 86 | 71.7 ± 24.6 | 83.9 ± 23.1 | <.0001 | 0.50 |
General health | 84 | 51.8 ± 24.0 | 50.8 ± 23.6 | 0.93 | 0.04 |
Vitality | 83 | 57.4 ± 20.3 | 58.6 ± 18.2 | 0.13 | 0.06 |
Social functioning | 86 | 73.8 ± 22.7 | 82.8 ± 20.9 | < 0.0001 | 0.40 |
Role emotional | 81 | 66.7 ± 42.1 | 78.6 ± 37.4 | 0.005 | 0.28 |
Mental health | 83 | 66.0 ± 19.3 | 67.0 ± 17.9 | 0.39 | 0.05 |
Physical component summary score | 75 | 45.7 ± 8.9 | 48.1 ± 8.3 | 0.002 | 0.27 |
Mental component summary score | 75 | 46.3 ± 10.7 | 48.2 ± 9.5 | 0.007 | 0.18 |