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Table 3 Logistic regression analysis of global health status/QoL of cervical cancer patients with socio-demographic, clinical characteristics, EORTC-QLQ-CX24 and EORTC-QLQ-C 30 subscale variables

From: Health-related quality of life and associated factors among cervical cancer patients at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

VariablesGlobal health status/QoL, n (%)Odds Ratio (95% CI)
AffectedUnaffectedCORAOR
Stage of cancer
 Stage I7 (2.1)3 (4.8)1.33 (0.21–8.28) 
 Stage II100 (29.5)29 (46.0)1.97 (0.53–7.20) 
 Stage III91 (26.8)17 (27.0)3.05 (0.80–11.60) 
 Stage IV134 (39.5)10 (15.9)7.65 (1.91–30.63) 
 Unknown7 (2.1)4 (6.3)1.00 
Treatment
 None119 (35)14 (21.9)3.09 (0.867–11.02) 
 Chemotherapy15 (4.4)1 (1.6)5.45 (0.53–55.80) 
 Radiotherapy143 (42.1)28 (43.8)1.85 (0.55–6.25) 
 Surgery and Chemotherapy5 (1.5)5 (7.8)0.36 (0.67–1.19) 
 Chemotherapy and Radiotherapy31 (9.1)7 (10.9)1.61 (3.94–6.58) 
 Surgery, Chemotherapy and Radiotherapy16 (4.7)5 (7.8)1.16 (0.25–5.33) 
 Surgery11 (3.2)4 (6.3)1.00 
Time since diagnosis
 Less than 12 Month227 (67)1 (1.0)5.45 (0.53–55.80) 
 1–5 years108 (31.9)22 (34.4)9.81 (2.71–35.48) 
 Above 5 years4 (1.2)8 (12.5)1 
Physical functioning297 (87.4)25 (39.1)10.77 (5.94–19.54)4.98 (2.16–11.49)
43 (12.6)39 (60.9)1.001.00
Role functioning290 (85.3)21 (32.8)11.8 (6.50–21.68) 
50 (14.7)43 (67.2)1.00 
Emotional functioning227 (66.8)15 (23.4)6.52 (3.52–12.20)5.25 (2.26–12.17)
113 (33.2)49 (76.6)1.001.00
Cognitive functioning134 (39.4)10 (15.6)3.51 (1.72–7.13) 
206 (60.6)54 (84.4)1.00 
Social functioning316 (92.9)30 (46.9)14.92 (7.84–28.38) 
24 (7.1)34 (53.1)1.00 
Fatigue313 (92.1)27 (42.2)15.88 (8.43–29.91) 
27 (7.9)37 (57.8)1.00 
Nausea and vomiting132 (38.8)6 (9.4)6.13 (2.57–14.61) 
208 (61.2)58 (90.6)1.00 
Pain318 (93.5)25 (39.1)22.54 (11.62–43.73)5.79 (2.30–14.57)
22 (6.5)39 (60.9)1.001.00
Dyspnea212 (62.4)14 (21.9)5.91 (3.14–11.12) 
128 (37.6)50 (78.1)1.00 
Insomnia250 (73.5)25 (39.1)4.33 (2.48–7.5) 
90 (26.5)39 (60.9)1.00 
Loss of appetite273 (80.3)26 (40.6)5.95 (3.38–10.48) 
67 (19.7)38 (59.4)1.00 
Constipation256 (75.3)25 (39.1)4.75 (2.71–8.31) 
84 (24.7)39 (60.9)1.00 
Diarrhea47 (13.8)2 (3.1)4.97 (1.17–21.01) 
293 (86.2)62 (96.9)1 
Financial difficulty306 (90)41 (64.1)5.04 (2.71–9.39) 
34 (10.0)23 (35.9)1.00 
Body image242 (71.2)22 (34.4)4.71 (2.67–8.30) 
98 (28.8)42 (65.6)1.00 
Sexual activity334 (98.5)61 (95.3)3.28 (0.76–14.10) 
5 (1.5)3 (4.7)1.00 
Sexual functioning16 (57.1)4 (30.8)3.00 (0.74–12.11) 
12 (42.)9 (69.2%)1.00 
Symptom experience279 (85.8)16 (27.6)15.92 (8.27–30.64)4.58 (1.95–10.79)
46 (14.2)42 (72.4)1.001.00
Peripheral neuropathy222 (65.3)25 (39.1)2.93 (1.69–5.08) 
118 (34.7)39 (60.9)1.00 
Menopausal symptoms285 (83.8)34 (53.1)4.57 (2.58–8.08) 
55 (16.2)30 (46.9)1.00