Table 3 Logistic regression analysis of global health status/QoL of cervical cancer patients with socio-demographic, clinical characteristics, EORTC-QLQ-CX24 and EORTC-QLQ-C 30 subscale variables
Variables | Global health status/QoL, n (%) | Odds Ratio (95% CI) | ||
|---|---|---|---|---|
Affected | Unaffected | COR | AOR | |
Stage of cancer | ||||
Stage I | 7 (2.1) | 3 (4.8) | 1.33 (0.21–8.28) | |
Stage II | 100 (29.5) | 29 (46.0) | 1.97 (0.53–7.20) | |
Stage III | 91 (26.8) | 17 (27.0) | 3.05 (0.80–11.60) | |
Stage IV | 134 (39.5) | 10 (15.9) | 7.65 (1.91–30.63) | |
Unknown | 7 (2.1) | 4 (6.3) | 1.00 | |
Treatment | ||||
None | 119 (35) | 14 (21.9) | 3.09 (0.867–11.02) | |
Chemotherapy | 15 (4.4) | 1 (1.6) | 5.45 (0.53–55.80) | |
Radiotherapy | 143 (42.1) | 28 (43.8) | 1.85 (0.55–6.25) | |
Surgery and Chemotherapy | 5 (1.5) | 5 (7.8) | 0.36 (0.67–1.19) | |
Chemotherapy and Radiotherapy | 31 (9.1) | 7 (10.9) | 1.61 (3.94–6.58) | |
Surgery, Chemotherapy and Radiotherapy | 16 (4.7) | 5 (7.8) | 1.16 (0.25–5.33) | |
Surgery | 11 (3.2) | 4 (6.3) | 1.00 | |
Time since diagnosis | ||||
Less than 12 Month | 227 (67) | 1 (1.0) | 5.45 (0.53–55.80) | |
1–5 years | 108 (31.9) | 22 (34.4) | 9.81 (2.71–35.48) | |
Above 5 years | 4 (1.2) | 8 (12.5) | 1 | |
Physical functioning | 297 (87.4) | 25 (39.1) | 10.77 (5.94–19.54) | 4.98 (2.16–11.49) |
43 (12.6) | 39 (60.9) | 1.00 | 1.00 | |
Role functioning | 290 (85.3) | 21 (32.8) | 11.8 (6.50–21.68) | |
50 (14.7) | 43 (67.2) | 1.00 | ||
Emotional functioning | 227 (66.8) | 15 (23.4) | 6.52 (3.52–12.20) | 5.25 (2.26–12.17) |
113 (33.2) | 49 (76.6) | 1.00 | 1.00 | |
Cognitive functioning | 134 (39.4) | 10 (15.6) | 3.51 (1.72–7.13) | |
206 (60.6) | 54 (84.4) | 1.00 | ||
Social functioning | 316 (92.9) | 30 (46.9) | 14.92 (7.84–28.38) | |
24 (7.1) | 34 (53.1) | 1.00 | ||
Fatigue | 313 (92.1) | 27 (42.2) | 15.88 (8.43–29.91) | |
27 (7.9) | 37 (57.8) | 1.00 | ||
Nausea and vomiting | 132 (38.8) | 6 (9.4) | 6.13 (2.57–14.61) | |
208 (61.2) | 58 (90.6) | 1.00 | ||
Pain | 318 (93.5) | 25 (39.1) | 22.54 (11.62–43.73) | 5.79 (2.30–14.57) |
22 (6.5) | 39 (60.9) | 1.00 | 1.00 | |
Dyspnea | 212 (62.4) | 14 (21.9) | 5.91 (3.14–11.12) | |
128 (37.6) | 50 (78.1) | 1.00 | ||
Insomnia | 250 (73.5) | 25 (39.1) | 4.33 (2.48–7.5) | |
90 (26.5) | 39 (60.9) | 1.00 | ||
Loss of appetite | 273 (80.3) | 26 (40.6) | 5.95 (3.38–10.48) | |
67 (19.7) | 38 (59.4) | 1.00 | ||
Constipation | 256 (75.3) | 25 (39.1) | 4.75 (2.71–8.31) | |
84 (24.7) | 39 (60.9) | 1.00 | ||
Diarrhea | 47 (13.8) | 2 (3.1) | 4.97 (1.17–21.01) | |
293 (86.2) | 62 (96.9) | 1 | ||
Financial difficulty | 306 (90) | 41 (64.1) | 5.04 (2.71–9.39) | |
34 (10.0) | 23 (35.9) | 1.00 | ||
Body image | 242 (71.2) | 22 (34.4) | 4.71 (2.67–8.30) | |
98 (28.8) | 42 (65.6) | 1.00 | ||
Sexual activity | 334 (98.5) | 61 (95.3) | 3.28 (0.76–14.10) | |
5 (1.5) | 3 (4.7) | 1.00 | ||
Sexual functioning | 16 (57.1) | 4 (30.8) | 3.00 (0.74–12.11) | |
12 (42.) | 9 (69.2%) | 1.00 | ||
Symptom experience | 279 (85.8) | 16 (27.6) | 15.92 (8.27–30.64) | 4.58 (1.95–10.79) |
46 (14.2) | 42 (72.4) | 1.00 | 1.00 | |
Peripheral neuropathy | 222 (65.3) | 25 (39.1) | 2.93 (1.69–5.08) | |
118 (34.7) | 39 (60.9) | 1.00 | ||
Menopausal symptoms | 285 (83.8) | 34 (53.1) | 4.57 (2.58–8.08) | |
55 (16.2) | 30 (46.9) | 1.00 | ||