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Table 3 Correlations between Fatigue Severity Scale and preference-based measures

From: Using the Fatigue Severity Scale to inform healthcare decision-making in multiple sclerosis: mapping to three quality-adjusted life-year measures (EQ-5D-3L, SF-6D, MSIS-8D)

FSS total score and PBM dimensions

rho

Observations

EQ-5D versus FSS total score

 Mobility

0.423

1035

 Self-care

0.385

1048

 Usual activities

0.524

1051

 Pain/Discomfort

0.361

1047

 Anxiety/Depression

0.292

1049

SF-6D versus FSS total score

 Physical functioning

0.547

649

 Role limitations

0.424

645

 Social functioning

0.530

644

 Pain

0.429

642

 Mental health

0.324

648

 Vitality

0.615

654

MSIS-8D versus FSS total score

 Physically demanding tasks

0.585

656

 Social and leisure activities

0.560

652

 Mobility (being stuck at home)

0.489

656

 Work or other daily activities

0.558

655

 Feeling mentally fatigued

0.582

656

 Feeling irritable, impatient or short-tempered

0.377

654

 Problems concentrating

0.450

654

 Feeling depressed

0.320

653

EQ-5D versus FSS item

1 My motivation is lower

−0.285

1040

2 Exercise brings on my fatigue

− 0.382

1038

3 I am easily fatigued

− 0.464

1040

4 Interferes with physical functioning

−0.471

1033

5 Causes frequent problems for me

−0.498

1039

6 Prevents sustained physical functioning

−0.527

1040

7 Interferes with duties and responsibilities

−0.536

1038

8 Among my most disabling symptoms

−0.336

1035

9 Interferes with work, family or social life

−0.482

1039

SF-6D versus FSS item

1 My motivation is lower

−0.400

614

2 Exercise brings on my fatigue

− 0.409

614

3 I am easily fatigued

−0.545

614

4 Interferes with physical functioning

−0.541

612

5 Causes frequent problems for me

−0.585

614

6 Prevents sustained physical functioning

−0.575

614

7 Interferes with duties and responsibilities

−0.623

613

8 Among my most disabling symptoms

−0.455

610

9 Interferes with work, family or social life

−0.603

614

MSIS-8D versus FSS item

1 My motivation is lower

−0.387

659

2 Exercise brings on my fatigue

−0.423

659

3 I am easily fatigued

−0.560

659

4 Interferes with physical functioning

−0.554

656

5 Causes frequent problems for me

−0.615

659

6 Prevents sustained physical functioning

−0.606

660

7 Interferes with duties and responsibilities

−0.637

660

8 Among my most disabling symptoms

−0.428

656

9 Interferes with work, family or social life

−0.596

659

  1. All coefficients significant at p < 0.0001
  2. PBM preference-based measure, FSS Fatigue Severity Scale, EQ-5D EuroQoL EQ-5D-3L, SF-6D Short-Form 6D, MSIS-8D Multiple Sclerosis Impact Scale – Eight Dimensions