Table 3 Studies of older Patients Undergoing Conservative Management (CM): Symptom
Author | Country | Study type | Type of intervention | Participants, n | Age(mean ± SD) | Dropout Rate,% | Exclusion Criteria | Setting | Outcome Measures | Results | Quality assessment |
|---|---|---|---|---|---|---|---|---|---|---|---|
Wan Zukiman et al. (2017) [24] | Malaysia | Prospective cohort study | Nondialysed, RRT | 187 (100 nondialysed, 87 RRT) | 60.97 (13.89) | 0 | Pregnancy; presence of any type of acute psychiatric disorder; lack of capacity to give informed consent; inability to communicate fluently in Malay or English language; or illiteracy. | Nephrology department | DSI | No difference in the prevalence of symptom burden and severity between two groups. | 7 |
Brown MA et al.(2015) [25] | Australia | Prospective cohort study | Nondialysis, predialysis | 467 | 74.5 | 15.4 | NA | Renal clinics | MSAS-SF | 57% had stable or improved symptoms over 12 months for nondialysis patients. | 8 |
Yong et al.(2009) [22] | Hong Kong | Prospective cohort study | Palliative-care, dialysis | 191 | 61.9 (12.3) | 6.3 | Cognitive impairment or known psychiatric illness | Hospital | 23 symptoms related to ESRD was assessed using NRS | No significant difference between the palliative care group and the dialysis group (P = 0.243) | 8 |
Murtagh et al. (2007) [28] | United Kingdom | Retrospective cohort study | CM, Advanced cancer | 66 | 82 (6.6) | 0 | Lacked capacity to consent to research participation | Renal units | MSAS-SF | Patients with ESRD have considerable symptom control needs, similar to advanced cancer populations. | 6 |
Saini et al.(2006) [29] | United Kingdom | Prospective cohort study | CM, terminal malignancy | 22 | 65 | 0 | Aged< 18 years,unclear themselves diagnosis and its implications | Renal clinic | MSAS-SF | Similar symptom burden for two groups. | 7 |