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Table 3 Comparison between Scores of Child/Proxy Relation to Clinical Characteristics and Treatment of Haemophilia

From: Health-related quality of life in children with haemophilia in China: a 4-year follow-up prospective cohort study

Clinical Characteristics
and Treatment of Haemophilia
Baseline Scores Follow-up Scores
CHOKLAT
Child self-report
CHOKLAT
Parent proxy report
SEC
Child self-report
SEC
Parent proxy report
CHOKLAT
Child self-report
CHOKLAT
Parent proxy report
SEC
Child self-report
SEC
Parent proxy report
Mean SD P 1 Mean SD P 1 Mean SD P 1 Mean SD P 1 Mean SD P 1 Mean SD P 1 Mean SD P 1 Mean SD P 1
Type of haemophilia A 60.12 (21.17) 0.763 61.13 (11.34) 0.861 60.44 (15.01) 0.898 55.70 (11.65) 0.309 63.56 (13.23) 0.154 66.42 (14.46) 0.279 65.61 (15.67) 0.570 62.80 (17.95) 0.290
  B 66.96 (−)   60.10 (18.73)   62.5 (−)   61.88 (19.06)   83.93 (−)   58.12 (23.54)   56.25 (−)   53.82 (12.53)  
Severity Severe 44.23 (25.50) 0.135 56.94 (14.96) 0.037 44.44 (7.35) 0.040 51.74 (7.52) 0.086 58.65 (15.80) 0.364 64.58 (17.35) 0.274 63.60 (15.53) 0.949 62.33 (19.04) 0.207
Moderate 71.67 (11.21)   64.92 (9.20)   63.53 (5.74)   60.13 (14.74)   69.47 (13.25)   68.09 (15.20)   66.41 (17.50)   64.03 (16.99)  
Mild 55.19 (22.02)   51.76 (8.98)   70.95 (20.34)   50.70 (1.39)   64.20 (10.24)   54.18 (9.14)   64.67 (14.52)   47.05 (6.12)  
Region of residence Rural 48.41 (17.80) 0.073 55.62 (14.00) 0.016 56.03 (13.63) 0.374 51.18 (12.04) 0.024 62.19 (13.48) 0.505 63.99 (15.44) 0.695 56.60 (11.10) 0.031 54.44 (9.09) 0.052
Urban 69.46 (18.09)   64.67 (9.30)   63.89 (14.91)   60.00 (11.90)   66.69 (14.27)   66.11 (16.24)   71.88 (15.32)   65.80 (19.86)  
Physical activity restriction No 70.69 (12.20) 0.007 62.70 (10.42) 0.062 63.89 (13.40) 0.283 57.66 (11.87) 0.196 66.31 (11.92) 0.365 66.31 (15.60) 0.430 65.95 (15.28) 0.670 62.15 (16.70) 0.701
Yes 40.70 (19.01)   53.82 (16.67)   54.07 (15.74)   51.22 (15.04)   59.03 (19.85)   61.01 (17.07)   62.07 (17.62)   59.28 (21.88)  
Type of treatment On-demand 52.64 (19.26) 0.045 56.81 (12.02) 0.005 60.06 (16.60) 0.860 51.13 (9.44) 0.000 61.49 (15.40) 0.167 58.82 (18.02) 0.003 57.26 (11.86) 0.000 51.41 (13.06) 0.000
Prophylactic 76.78 (11.17)   67.19 (9.63)   61.72 (10.32)   64.24 (12.81)   71.10 (6.57)   73.37 (6.72)   80.73 (7.24)   74.23 (13.65)  
Home injection No 59.96 (22.40) 0.870 60.68 (13.00) 0.901 60.02 (16.57) 0.850 56.26 (13.60) 0.671 62.18 (15.43) 0.221 60.97 (16.95) 0.010 59.35 (13.62) 0.006 55.02 (15.27) 0.000
Yes 62.14 (18.26)   61.23 (11.34)   61.81 (10.44)   58.22 (11.72)   71.21 (3.27)   74.79 (6.47)   80.00 (7.85)   75.90 (13.05)  
  1. P ≤ 0.05: significant
  2. P ≤ 0.01: highly significant
  3. 1Tested by ANOVA test
  4. Value in bold indicate significant P value