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Table 3 Comparison between Scores of Child/Proxy Relation to Clinical Characteristics and Treatment of Haemophilia

From: Health-related quality of life in children with haemophilia in China: a 4-year follow-up prospective cohort study

Clinical Characteristics

and Treatment of Haemophilia

Baseline Scores

Follow-up Scores

CHOKLAT

Child self-report

CHOKLAT

Parent proxy report

SEC

Child self-report

SEC

Parent proxy report

CHOKLAT

Child self-report

CHOKLAT

Parent proxy report

SEC

Child self-report

SEC

Parent proxy report

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Mean SD

P 1

Type of haemophilia

A

60.12 (21.17)

0.763

61.13 (11.34)

0.861

60.44 (15.01)

0.898

55.70 (11.65)

0.309

63.56 (13.23)

0.154

66.42 (14.46)

0.279

65.61 (15.67)

0.570

62.80 (17.95)

0.290

 

B

66.96 (−)

 

60.10 (18.73)

 

62.5 (−)

 

61.88 (19.06)

 

83.93 (−)

 

58.12 (23.54)

 

56.25 (−)

 

53.82 (12.53)

 

Severity

Severe

44.23 (25.50)

0.135

56.94 (14.96)

0.037

44.44 (7.35)

0.040

51.74 (7.52)

0.086

58.65 (15.80)

0.364

64.58 (17.35)

0.274

63.60 (15.53)

0.949

62.33 (19.04)

0.207

Moderate

71.67 (11.21)

 

64.92 (9.20)

 

63.53 (5.74)

 

60.13 (14.74)

 

69.47 (13.25)

 

68.09 (15.20)

 

66.41 (17.50)

 

64.03 (16.99)

 

Mild

55.19 (22.02)

 

51.76 (8.98)

 

70.95 (20.34)

 

50.70 (1.39)

 

64.20 (10.24)

 

54.18 (9.14)

 

64.67 (14.52)

 

47.05 (6.12)

 

Region of residence

Rural

48.41 (17.80)

0.073

55.62 (14.00)

0.016

56.03 (13.63)

0.374

51.18 (12.04)

0.024

62.19 (13.48)

0.505

63.99 (15.44)

0.695

56.60 (11.10)

0.031

54.44 (9.09)

0.052

Urban

69.46 (18.09)

 

64.67 (9.30)

 

63.89 (14.91)

 

60.00 (11.90)

 

66.69 (14.27)

 

66.11 (16.24)

 

71.88 (15.32)

 

65.80 (19.86)

 

Physical activity restriction

No

70.69 (12.20)

0.007

62.70 (10.42)

0.062

63.89 (13.40)

0.283

57.66 (11.87)

0.196

66.31 (11.92)

0.365

66.31 (15.60)

0.430

65.95 (15.28)

0.670

62.15 (16.70)

0.701

Yes

40.70 (19.01)

 

53.82 (16.67)

 

54.07 (15.74)

 

51.22 (15.04)

 

59.03 (19.85)

 

61.01 (17.07)

 

62.07 (17.62)

 

59.28 (21.88)

 

Type of treatment

On-demand

52.64 (19.26)

0.045

56.81 (12.02)

0.005

60.06 (16.60)

0.860

51.13 (9.44)

0.000

61.49 (15.40)

0.167

58.82 (18.02)

0.003

57.26 (11.86)

0.000

51.41 (13.06)

0.000

Prophylactic

76.78 (11.17)

 

67.19 (9.63)

 

61.72 (10.32)

 

64.24 (12.81)

 

71.10 (6.57)

 

73.37 (6.72)

 

80.73 (7.24)

 

74.23 (13.65)

 

Home injection

No

59.96 (22.40)

0.870

60.68 (13.00)

0.901

60.02 (16.57)

0.850

56.26 (13.60)

0.671

62.18 (15.43)

0.221

60.97 (16.95)

0.010

59.35 (13.62)

0.006

55.02 (15.27)

0.000

Yes

62.14 (18.26)

 

61.23 (11.34)

 

61.81 (10.44)

 

58.22 (11.72)

 

71.21 (3.27)

 

74.79 (6.47)

 

80.00 (7.85)

 

75.90 (13.05)

 
  1. P ≤ 0.05: significant
  2. P ≤ 0.01: highly significant
  3. 1Tested by ANOVA test
  4. Value in bold indicate significant P value