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Table 5 GRADE Summary of findings. Outcome: Sexual impairment

From: Quality of life in bladder cancer patients receiving medical oncological treatment; a systematic review of the literature

 

GRADE issues

Overall GRADE rating

 

Nb. of studies

Risk of bias

Inconsistency

Indirectness

Imprecision

Publication bias

 

Before diagnosis

1 [12]

X1, X2

  

X3

 

Before treatment

1 [18]

X1

  

X3

 

During treatment

2 [16, 18]

 

X4

X5

X3

 

≤ 6 months after treatment

1 [18]

X1

  

X3

 

> 6 months after treatment

7 [20, 21, 23,24,25,26, 35]

 

X6

  

None apparent7

  1. 1Only one study represented
  2. 2Selected population
  3. 3Small number of patients
  4. 4Large difference in populations hence diverging scores, despite same instrument used
  5. 5Only one study representing metastatic population, no studies representing neoadjuvant population
  6. 6Large range between scores despite comparable study populations, presumably due to different instruments used, incl. Non-validated instrument
  7. 7As estimated by funnel plo
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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