Table 1 Baseline characteristics of patients with complete CAT data at baseline, complete pre- and post-PR CAT data and patients who dropped out
Complete baseline N = 497 | Complete pre- and post N = 381 | Dropout N = 116 | |
|---|---|---|---|
Age (years)# | 64.0 (57.5–71.0) | 64.0 (58.0–71.0) | 64.0 (54.3–72.0) |
Male gender, n (%) | 273 (54.9) | 204 (53.5) | 69 (59.5) |
BMI (kg/m2)# | 25.6 (21.7–29.7) | 25.7 (21.7–29.0) | 25.1 (21.4–29.6) |
GOLD stage, n (%) | |||
I | 37 (7.4) | 28 (7.3) | 9 (7.8) |
II | 172 (34.6) | 137 (36.0) | 35 (30.2) |
III | 186 (37.4) | 136 (35.7) | 50 (43.1) |
IV | 102 (20.5) | 80 (21.0) | 22 (19.0) |
GOLD grade§, n (%) | |||
A | 14 (2.8) | 10 (2.6) | 4 (3.4) |
B | 158 (31.8) | 132 (34.6) | 26 (22.4) |
C | 14 (2.8) | 11 (2.9) | 3 (2.6) |
D | 311 (62.6) | 228 (59.8) | 83 (71.6) |
FEV1 (L)# | 1.2 (0.8–1.7) | 1.1 (0.8–1.7) | 1.2 (0.8–1.6) |
FEV1 (% pred.)# | 46.0 (32.0–63.0) | 46.7 (32.0–62.5) | 44.5 (31.8–64.0) |
FEV1/FVC, %# | 35.0 (28.0–45.9) | 35.3 (27.9–44.9) | 34.5 (28.0–48.9) |
DLCO (mmol/min./kPa)#1 | 3.7 (3.0–5.0) | 3.7 (3.0–5.1) | 3.6 (2.6–4.8) |
DLCO (%)#1 | 46.0 (37.0–59.0) | 47.0 (38.0–60.1) | 44.9 (34.8–56.8)* |
Current smokers, n (%)2 | 110 (22.1) | 71 (18.6) | 39 (33.9)* |
Pack years#3 | 40 (30–50) | 40 (30–50) | 40 (30–50) |
LTOT, n (%) | 120 (24.1) | 94 (24.7) | 26 (22.4) |
6MWD, m4 | 425 (123) | 436 (119) | 391 (133)* |
mMRC, n (%)4 | |||
0 | 10 (2.0) | 10 (2.7) | 0 (0.0) |
1 | 81 (16.5) | 61 (16.2) | 20 (17.4) |
2 | 187 (38.0) | 157 (41.6) | 30 (26.1)* |
3 | 124 (25.2) | 83 (22.0) | 41 (35.7)* |
4 | 90 (18.3) | 66 (17.5) | 24 (20.9) |
CAT score, points# | |||
Total score | 22.0 (17.5–26.0) | 22.0 (17.0–26.0) | 22.0 (18.0–27.0) |
Cough | 3.0 (2.0–3.0) | 3.0 (2.0–3.0) | 3.0 (2.0–3.0) |
Phlegm | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) |
Chest tightness | 1.0 (0.0–2.0) | 1.0 (0.0–2.0) | 1.0 (0.0–3.0) |
Breathlessness | 4.0 (4.0–5.0) | 4.0 (4.0–5.0) | 5.0 (3.3–5.0) |
Limited activity | 3.0 (2.0–4.0) | 3.0 (2.0–4.0) | 3.0 (2.0–5.0) |
Confidence leaving home | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) |
Sleeplessness | 3.0 (1.0–4.0) | 3.0 (1.0–4.0) | 3.0 (1.0–4.0) |
Energy | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | 3.0 (3.0–4.0) |
CAT total score ≥ 10 points, n (%) | 469 (94.4) | 360 (94.5) | 109 (94.0) |
CAT total score ≥ 18 points, n (%) | 373 (75.1) | 285 (74.8) | 88 (75.9) |