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Table 3 Quality of life measures by clinical factor and treatment side effect in cancer among cancer patients in Malaysia (n = 1620)

From: Determinants of quality of life among Malaysian cancer patients: a cross-sectional study

Clinical factor Physical health Psychological health Social relationships Environment
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
Type of Cancer
 Breast 65.30 ± 19.13 58.35 ± 19.56 57.90 ± 24.65 63.74 ± 18.86
 Ovarian 75.03 ± 23.19 77.00 ± 14.21 72.70 ± 22.21 72.22 ± 23.93
 Cervical 68.43 ± 13.94 59.76 ± 15.32 67.62 ± 17.64 67.86 ± 14.38
 Colorectal 61.98 ± 20.17 60.05 ± 17.64 58.43 ± 23.23 61.28 ± 20.88
 Lymphoma 60.45 ± 19.56 55.66 ± 18.88 56.39 ± 20.86 58.60 ± 18.51
 Stomach 60.67 ± 22.25 60.47 ± 24.27 49.43 ± 22.36 59.30 ± 24.92
 Others 66.89 ± 22.45 64.36 ± 18.06 56.96 ± 25.81 66.32 ± 21.83
 Statistics F = 7.25, p < 0.00* F = 11.47, p < 0.00* F = 11.87, p < 0.00* F = 6.58, p < 0.00*
Cancer stage
 I 67.01 ± 20.46 67.08 ± 22.53 62.08 ± 27.54 67.08 ± 20.06
 II 63.04 ± 18.33 59.93 ± 18.74 56.59 ± 22.04 62.18 ± 19.40
 III 67.92 ± 18.61 60.16 ± 19.06 61.92 ± 23.49 66.41 ± 18.95
 IV 60.90 ± 21.63 57.57 ± 17.50 54.79 ± 23.07 59.61 ± 21.88
 Statistics F = 13.80, p < 0.001* F = 8.56, p < 0.001* F = 11.07, p < 0.001* F = 13.52, p < 0.001*
Type of cancer treatment
 Chemotherapy 64.84 ± 19.91 60.91 ± 18.97 58.49 ± 23.58 63.63 ± 20.22
 Chemotherapy & radiation 60.04 ± 22.43 54.43 ± 20.88 57.78 ± 25.80 59.34 ± 23.13
 Statistics t = 2.67, p < 0.008* t = 3.79, p < 0.001* t = 0.33, p < 0.73 t = 2.34, p < 0.01*
Cycle of cancer treatment
 1st cycle 68.43 ± 18.21 64.38 ± 19.73 64.43 ± 22.92 67.54 ± 18.65
 2nd cycle 61.89 ± 20.95 57.80 ± 18.77 54.60 ± 23.52 60.54 ± 21.17
 Statistic t = 6.44, p < 0.001* t = 6.80, p < 0.001* t = 8.28, p < 0.001* t = 6.79, p < 0.001*
Pain due to cancer
 Yes 60.74 ± 21.79 57.08 ± 17.44 56.08 ± 23.20 59.13 ± 22.04
 No 67.58 ± 18.12 63.15 ± 20.20 60.43 ± 24.08 66.78 ± 18.41
 Statistic t = −6.88, p < 0.001* t = − 6.41, p < 0.001* t = − 3.68, p < 0.001* t = − 7.61, p < 0.001*
TREATMENT SIDE EFFECT
Treatment side effect
 No side effect 81.97 ± 14.68 76.40 ± 8.68 79.97 ± 8.60 82.98 ± 12.24
 One side effect 82.75 ± 10.65 79.74 ± 10.52 83.09 ± 7.61 79.98 ± 10.40
 Two side effect 81.43 ± 10.70 81.35 ± 6.22 81.81 ± 9.71 79.79 ± 8.78
 ≥ Three side effect 59.73 ± 19.34 55.18 ± 18.02 52.20 ± 22.66 58.52 ± 19.99
 Statistic F = 135.82, p < 0.001* F = 201.08, p < 0.001* F = 183.96, p < 0.001* F = 133.99, p < 0.001*
Vomiting
 Yes 57.45 ± 18.89 52.43 ± 16.60 49.44 ± 21.47 56.23 ± 19.61
 No 81.28 ± 11.25 79.49 ± 8.82 80.11 ± 12.31 80.21 ± 10.05
 Statistic t = −25.66, p < 0.001* t = − 33.58, p < 0.001* t = − 29.19, p < 0.001* t = − 25.29, p < 0.001*
Nausea
 Yes 54.07 ± 16.95 49.55 ± 14.87 47.79 ± 20.55 53.11 ± 18.07
 No 82.68 ± 9.81 79.39 ± 7.88 77.17 ± 16.32 81.13 ± 9.23
 Statistic t = −37.46, p < 0.001* t = − 45.13, p < 0.001* t = − 29.71, p < 0.001* t = − 35.04, p < 0.001*
Anorexia
 Yes 59.37 ± 19.43 54.72 ± 17.86 51.68 ± 22.66 58.10 ± 20.05
 No 80.82 ± 12.29 78.59 ± 9.83 80.24 ± 10.46 79.94 ± 10.78
 Statistic t = −20.37, p < 0.001* t = − 24.99, p < 0.001* t = − 23.87, p < 0.001* t = − 20.41, p < 0.001*
Fatigue
 Yes 62.18 ± 19.91 58.20 ± 19.06 55.55 ± 23.59 60.93 ± 20.29
 No 80.31 ± 13.93 75.57 ± 12.11 78.64 ± 12.63 79.63 ± 13.38
 Statistic t = −12.50, p < 0.001* t = − 12.59, p < 0.001* t = − 13.62, p < 0.001* t = − 12.70, p < 0.001*
Hair loss
 Yes 54.75 ± 27.84 56.96 ± 19.86 52.46 ± 27.06 54.29 ± 28.61
 No 66.01 ± 18.17 60.91 ± 19.06 59.40 ± 23.06 64.72 ± 18.48
 Statistic t = −7.92, p < 0.00* t = − 2.87, p < 0.004* t = − 4.08, p < 0.001* t = − 7.20, p < 0.001*
Bleeding
 Yes 48.53 ± 16.38 45.05 ± 12.56 39.11 ± 16.62 47.56 ± 17.44
 No 76.18 ± 13.60 71.68 ± 14.98 72.70 ± 17.29 74.86 ± 13.79
 Statistic t = −37.05, p < 0.001* t = − 37.83, p < 0.001* t = − 39.27, p < 0.001* t = − 35.14, p < 0.001*
Infection
 Yes 58.14 ± 19.09 53.47 ± 17.18 50.48 ± 22.05 57.05 ± 19.94
 No 81.06 ± 11.77 78.57 ± 10.41 79.44 ± 12.89 79.66 ± 10.55
 Statistic t = −23.67, p < 0.001* t = − 28.87, p < 0.001* t = − 26.06, p < 0.001* t = − 22.73, p < 0.001*
  1. *Significant at p < 0.05