Skip to main content

Table 3 Mean (SD) of cognitive tests and mood scales in males and females at baseline and week 24 for the low and high dose group

From: Effect of low-normal and high-normal IGF-1 levels on memory and wellbeing during growth hormone replacement therapy: a randomized clinical trial in adult growth hormone deficiency

  Males Females
Low Dose
n = 9
High Dose
n = 10
Low Dose
n = 6
High Dose
n = 5
Baseline Week 24 Baseline Week 24 Baseline Week 24 Baseline Week 24
MEMORY
 PRM (%) 91.2 (8.7) 92.6 (5.8) 85.8 (15.2) 91.2 (8.2) 88.9 (8.2) 90.3 (10.1) 91.7 (8.3) 91.7 (11.4)
 SWM TE 15.3 (19.7) 16.8 (14.7) 28 (24.7) 21.7 (17.2) 42 (24.9) 26(23.3)** 27.4 (9.4) 34.4 (14.3)
 SWM STR 38.3 (11.1) 36.3 (8.8) 43.3 (9) 40.1(7.8)** 44.3 (6.4) 40.8 (9.4) 43.4 (2.1) 46 (3.5)
MOOD
 Depression 2.9 (3.2) 4.1 (6.7) 2.6 (3.3) 1.2 (2.5) 4.3 (4.9) 7 (7.3) 5.2 (3.1) 5 (6)
 Anger 5.4 (6.2) 4.9 (5.4) 4.8 (4.7) 4.2 (4.2) 9 (7.7) 7 (5.8) 5.2 (5.7) 5.6 (7.2)
 Fatigue 5.4 (6) 5.3 (6.6) 3.9 (3.4) 3 (1.8) 9.8 (7.5) 13.2 (3.7) 4.4 (4.7) 3.6 (3.8)
 Tension 3 (2.9) 3.7 (4) 4.5 (4.6) 3.7 (3.6) 4.5 (4.6) 7.8 (5.3) 6.2 (5.5) 5 (5.4)*
 Vigor 11.3 (4.1) 12.8 (4.8) 12.5 (3.4) 11.8 (3.9) 11.5 (5.2) 7.8 (4)* 12.8 (1.5) 12 (2.7)
  1. PRM (%) = Pattern Recognition Memory (percent correct)
  2. SWM TE Spatial Working Memory Total Errors, SWM STR Spatial Working Memory Strategy
  3. * p < 0.05, ** p ≤ 0.01; week 24 versus baseline