Patient-reported outcome measures used in patients with primary sclerosing cholangitis: a systematic review

Table 3 Results of measurement properties of NIDDK-QA

PROM (Author, Year)	Total sample size	PSC sample size	Domains	Test retest reliability (Pearson Correlation)	Internal consistency (Cronbach’s Alpha)
NIDDK-QA (Kim, 2000)	96	17	Liver symptoms men women	0.94	Men = 0.94, women =0.87
			Physical function	0.99	0.88
			Health satisfaction	0.82	NR
			Overall well being	0.83	0.91
				Time interval of 2 weeks
NIDDK-QA (Gross, 1999)	157	92	Symptoms	NR	0.81 & 0.85
			Functioning	NR	0.82 & 0.88
			Index of General Affect (IGA)	NR	0.91 & 0.93
PSC PROM (Younossi, 2017)	102	Test retest n = 53 Internal consistency n = 155	PSC Symptoms	0.84	0.89
			Physical Function	0.83	0.91
			Activities of Daily Living	0.85	0.86
			Work Productivity	0.7	0.93
			Role Function	0.83	0.91
			Emotional Impact	0.82	0.91
			Social/Leisure Impact	0.8	0.93
			Quality of Life	0.79	0.94
			Total Impact of Symptoms	0.88

NIDDK-QA National institute of diabetes and digestive and kidney disease liver transplant questionnaire, PSC PRO Primary Sclerosing Cholangitis Patient Reported Outcome

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