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Table 2 Comparison between different HQOL scores regarding demographic and laboratory data

From: Health-related quality of life in pediatric and adolescent patients with transfusion-dependent ß-thalassemia in upper Egypt (single center study)

Parameter

Physical score

Emotional score

Social score

School Achievement score

Psychological score

Total score

Mean ± SD

p value

Mean

p value

Mean

p value

Mean

p value

Mean

p value

Mean

p value

Age

8-12

40.3 ± 22.6

 

53.1 ± 16.8

 

52.4 ± 21.7

 

40.8 ± 16.2

 

47.9 ± 15.2

 

46.8 ± 15.9

 

13-18

31.6 ± 17.1

0.12

43.5 ± 16.2

0.03*

39.04 ± 18.1

0.013*

34.9 ± 13.9

0.14

41.1 ± 10.2

0.04*

37.7 ± 10.7

0.09

Sex

Male

39.5 ± 22.3

 

49.1 ± 16.8

 

48.1 ± 20.5

 

40.2 ± 14.6

 

45.6 ± 14.1

 

44.3 ± 14.6

 

female

31.6 ± 16.9

0.16

49.9 ± 17.7

0.85

45.2 ± 23.2

0.62

34.9 ± 19.02

0.2

44.5 ± 13.4

0.78

41.2 ± 15.1

0.29

Household income

< 500

54.1 ± 16.1

 

56 ± 19.1

 

61.6 ± 13.1

 

47.5 ± 14.7

 

52.4 ± 10.1

 

54.3 ± 9.1

 

500-1000

33.2 ± 21.8

0.45

46.6 ± 18.1

0.04*

44.1 ± 23.5

0.9

35.8 ± 15.3

0.78

43.8 ± 15.4

0.27

40.6 ± 16.1

0.39

> 1000

28.3 ± 13.5

 

48.7 ± 10.5

 

39.9 ± 16.8

 

35.6 ± 14.2

 

41.4 ± 11.3

 

38.3 ± 11.1

 

Type of chelation

Non

32.1 ± 19.6

 

41.8 ± 13.6

 

43.8 ± 19.7

0.54

38.1 ± 16

 

40 ± 9.4

 

38.9 ± 10.4

 

Oral

49.6 ± 24.2

0.5

55.3 ± 18.8

0.82

58 ± 25.1

 

41.9 ± 16.6

0.27

54.9 ± 10.8

0.42

51.8 ± 16.4

0.44

Sc

39.7 ± 18.8

 

55.5 ± 17.6

 

51.5 ± 18.7

 

44.3 ± 12.6

 

48.9 ± 11.8

 

48 ± 11.4

 

Splenectomy

No

37.3 ± 23.9

0.54

52.1 ± 23.9

0.46

48.9 ± 24.1

0.63

40.7 ± 16.3

0.74

44.1 ± 9.8

0.08

45 ± 17.5

0.3

Yes

36.5 ± 17.3

 

46.3 ± 14.9

 

45.2 ± 17.9

 

36.1 ± 14.5

 

44.9 ± 17.5

 

41.4 ± 10.9

 

Educational level

Primary school

34.9 ± 19.8

0.81

51.2 ± 16.4

0.46

43.7 ± 15.3

0.72

35.7 ± 14.4

0.21

43.6 ± 13.1

0.29

41.3 ± 13.1

0.27

Secondary school

39.7 ± 21.9

 

52 ± 17.33

 

50.6 ± 23.6

 

40.04 ± 16.6

 

47.1 ± 15.7

 

45. ±16.4

 

No school

31.8 ± 19.7

 

4.9 ± 14.6

 

42 ± 19.7

 

37.9 ± 14.2

 

42.3 ± 8.1

 

38.8 ± 10.6

 

HCV infection

Positive

28.4 ± 12.4

0.38

45.4 ± 11.9

0.87

39.3 ± 13.5

0.3

39.5 ± 14.3

0.45

41.01 ± 10.7

0.3

38.7 ± 10.6

0.31

negative

41.4 ± 23.1

 

51.4 ± 18.9

 

51.3 ± 23.5

 

38.1 ± 16.2

 

47.5 ± 14.7

 

45.6 ± 16.1

Pre-transfusion Hb%

< 9 g%

49.9 ± 12.4

0.4

56.2 + 14.7

0.51

41.8 + 11.1

0.28

55.8 + 21.5

0.33

56.7 ± 18.5

0.23

51.2 ± 12.6

0.15

≥9 g%

50.7 ± 6.6

 

53.3 + 18.1

 

45.6 + 12.4

 

52.9 + 14.8

 

54.7 ± 5.6

 

50.9 ± 13.1

Serum ferritin (ng/ml)

< 2500

41.7 ± 21.6

0.31

48.9 ± 19.1

0.09

52.3 ± 23.5

0.5

36.7 ± 15.1

0.06

46.1 ± 15.9

0.2

44.9 ± 15.1

0.07

≥2500

32.9 ± 19.7

 

49.6 ± 15.4

 

42.8 ± 18.5

 

40.03 ± 15.9

 

44.5 ± 12.9

 

41.9 ± 14.6

Age of start transfusion

r

0.19

0.09

0.2

0.04

0.13

0.17

p-value

0.1

0.4

0.08

0.7

0.3

0.1

Age of start chelation

r

0.17

0.23

0.09

0.13

0.17

0.19

p-value

0.1

0.06

0.4

0.2

0.1

0.1

  1. HCV Hepatitis C virus, Hb Hemoglobin, SC Subcutaneous. * = Significant (p < 0.05)
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