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Table 3 Comparison dsd-LIFE participants to reference populations per country

From: Multicentre cross-sectional clinical evaluation study about quality of life in adults with disorders/differences of sex development (DSD) compared to country specific reference populations (dsd-LIFE)

Country

WHOQOL-BREF

Reference population

Study participants (dsd-LIFE)

p-value

  

n

Mean

SD

n

Mean

SD

Mean

SD

 
 

[0–100]

[0–100]

[4-20]

[4-20]

France

 

Physical health

Healthy

12,186

80.2

11.0

249

71.2

16.8

15.4

2.7

4.1 E-36

 

Psychological

 

12,186

67.7

11.0

251

65.7

17.4

14.5

2.8

4.5 E-03

 

Social relationships

 

12,186

75.4

11.0

250

65.7

19.6

14.5

3.1

1.9 E-41

 

Environment

 

249

73.9

14.6

15.7

2.3

 

Physical health

Non-healthy

4192

66.4

19.4

249

71.2

16.8

15.4

2.7

1.4 E-04

 

Psychological

 

4192

64.9

13.0

251

65.7

17.4

14.5

2.8

n.s.*

 

Social relationships

 

4192

71.5

19.4

250

65.7

19.6

14.5

3.1

3.9 E-06

 

Environment

 

249

73.3

14.6

15.7

2.3

Germany

 

Physical health

Healthy

2052

76.9

17.7

238

73.0

19.3

15.7

3.1

1.3 E-03

 

Psychological

 

2055

74.0

15.7

239

65.0

19.3

14.4

3.1

4.6 E-16

 

Social relationships

 

2048

71.8

18.5

239

62.3

22.2

14.0

3.6

2.9 E-13

 

Environment

 

2053

70.4

14.2

239

75.1

14.6

16.0

2.3

1.6 E-06

 

Physical health

Non-healthy (physical)

261

53.4

20.3

238

73.0

19.3

15.7

3.1

2.0 E-25

 

Psychological

 

261

62.7

16.3

239

65.0

19.3

14.4

3.1

n.s.*

 

Social relationships

 

261

68.0

16.9

239

62.3

22.2

14.0

3.6

1.3 E-03

 

Environment

 

261

67.2

13.4

239

75.1

14.6

16.0

2.3

7.4 E-10

 

Physical health

Non-healthy (mental)

98

58.5

17.7

238

73.0

19.3

15.7

3.1

5.1 E-10

 

Psychological

 

98

52.0

19.5

239

65.0

19.3

14.4

3.1

4.4 E-08

 

Social relationships

 

98

50.9

26.5

239

62.3

22.2

14.0

3.6

6.3 E-05

 

Environment

 

98

59.3

18.8

239

75.1

14.6

16.0

2.3

3.4 E-15

Netherlands

 

Physical health

Healthy

218

15.2

2.6

229

67.3

20.2

14.8

3.2

n.s.*

 

Psychological

 

218

14.4

2.0

230

61.9

18.1

13.9

2.9

n.s.*

 

Social relationships

 

218

15.4

2.9

230

62.6

21.0

14.0

3.4

3.9 E-06

 

Environment

 

218

15.8

2.0

230

72.6

15.1

15.6

2.4

n.s.*

 

Physical health

Non-healthy

410

11.8

3.0

229

67.3

20.2

14.8

3.2

4.7 E-29

 

Psychological

 

410

10.5

2.5

230

61.9

18.1

13.9

2.9

1.4 E-46

 

Social relationships

 

410

12.8

3.5

230

62.6

21.0

14.0

3.4

3.3 E-05

 

Environment

 

410

13.5

2.5

230

72.6

15.1

15.6

2.4

1.3 E-22

Poland

 

Physical health

Healthy

438

15.8

2.2

107

69.1

14.0

15.1

2.2

2.5 E-03

 

Psychological

 

438

13.8

2.5

107

63.5

17.4

14.2

2.8

n.s.*

 

Social relationships

 

438

14.9

3.0

107

59.5

19.1

13.5

3.1

4.5 E-05

 

Environment

 

438

13.1

2.4

107

71.0

13.1

15.4

2.1

1.2 E-17

 

Physical health

Non-healthy

470

13.1

2.7

107

69.1

14.0

15.1

2.2

7.0 E-12

 

Psychological

 

470

12.5

2.6

107

63.5

17.4

14.2

2.8

6.8 E-09

 

Social relationships

 

470

13.4

3.1

107

59.5

19.1

13.5

3.1

n.s.*

 

Environment

 

470

12.8

2.4

107

71.0

13.1

15.4

2.1

5.8 E-23

Sweden

 

Physical health

 

119

70.3

18.0

15.3

2.9

 

Psychological

 

119

63.7

17.3

14.2

2.8

 

Social relationships

 

119

61.3

20.6

13.8

3.3

 

Environment

 

119

72.5

14.0

15.6

2.2

United Kingdom

 

Physical health

Healthy

1324

76.5

16.2

42

64.1

20.1

14.3

3.2

1.5 E-06

 

Psychological

 

1324

67.8

15.6

42

60.4

17.5

13.7

2.8

2.6 E-03

 

Social relationships

 

1324

70.5

20.7

42

57.9

24.0

13.3

3.8

1.2 E-04

 

Environment

 

1324

68.2

13.8

42

68.5

18.3

15.0

2.9

n.s.*

 

Physical health

Non-healthy

1864

57.0

22.7

42

64.1

20.1

14.3

3.2

4.4 E-02

 

Psychological

 

1864

58.3

19.3

42

60.4

17.5

13.7

2.8

n.s.*

 

Social relationships

 

1864

62.8

23.2

42

57.9

24.0

13.3

3.8

n.s.*

 

Environment

 

1864

64.9

16.9

42

68.5

18.3

15.0

2.9

n.s.*

  1. Legend: n.s.* not significant after Bonferroni correction
  2. (The values of the WHOQOL-BREF are shown with range 0–100 as well as range 4–20 for our study participants; reference population: value 0–100 for France, Germany and UK and value 4–20 for Netherlands and Poland)