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Table 2 Instrument Scores at Day 1 and Week 12 for RA-BEAM and RA-BUILD

From: Psychometric properties of morning joint stiffness duration and severity measures in patients with moderately to severely active rheumatoid arthritis

Instrument

RA-BEAMa

RA-BUILDb

Day 1

Week 12

Day 1

Week 12

Duration of MJS, Mean (SD)

152.8 (180.8)

96.7 (144.7)

160.7 (174.8)

103.5 (147.5)

Severity of MJS, Mean (SD)

5.8 (2.2)

3.5 (2.4)

5.7 (2.1)

3.7 (2.4)

Severity of Worst Tiredness, Mean (SD)

5.8 (2.1)

4.0 (2.3)

6.0 (2.1)

4.1 (2.4)

Severity of Worst Joint Pain, Mean (SD)

6.1 (2.0)

4.0 (2.3)

6.0 (2.1)

4.2 (2.4)

Patient’s Assessment of Pain, Mean (SD)

60.8 (22.3)

34.9 (24.1)

58.0 (22.1)

36.5 (24.9)

Patient’s Global Assessment of Disease Activity, Mean (SD)

62.4 (21.8)

36.3 (23.5)

60.7 (21.1)

37.7 (24.0)

SF-36

 Role Physical Domain, Mean (SD)

35.5 (10.4)

41.8 (10.2)

35.3 (9.2)

40.7 (9.6)

 Bodily Pain Domain, Mean (SD)

34.7 (7.8)

42.5 (8.7)

34.9 (7.6)

41.9 (9.0)

 General Health Domain, Mean (SD)

36.8 (8.5)

41.6 (8.9)

36.8 (8.3)

42.0 (9.4)

 Social Functioning Domain, Mean (SD)

40.8 (11.6)

45.4 (10.5)

40.2 (11.2)

44.7 (10.3)

 Vitality Domain, Mean (SD)

43.7 (10.0)

49.4 (9.8)

41.9 (10.1)

48.4 (10.0)

 Role Emotional Domain, Mean (SD)

41.1 (12.6)

45.5 (10.9)

40.9 (12.3)

44.8 (11.2)

 Mental Health Domain, Mean (SD)

43.0 (11.3)

47.1 (10.7)

42.9 (11.6)

47.1 (11.3)

 Physical Functioning Domain, Mean (SD)

32.2 (10.4)

38.7 (10.9)

32.2 (10.2)

38.2 (10.9)

 Mental Component Score, Mean (SD)

46.4 (11.8)

49.8 (10.8)

45.7 (11.8)

49.3 (11.1)

 Physical Component Score, Mean (SD)

32.3 (8.6)

39.4 (9.3)

32.3 (8.3)

38.8 (9.4)

QIDS-SR16 Total Score, Mean (SD)

8.0 (5.0)

5.9 (4.2)

8.4 (4.9)

6.2 (4.3)

HAQ-DI Total Score, Mean (SD)

1.56 (0.68)

1.03 (0.70)

1.52 (0.61)

1.03 (0.66)

PhGA, Mean (SD)

65.0 (16.9)

31.0 (21.7)

63.5 (17.4)

33.9 (22.4)

CDAI, Mean (SD)

37.83 (12.55)

18.68 (13.54)

36.05 (12.12)

18.04 (13.15)

DAS28-ESR, Mean (SD)

6.43 (0.97)

4.62 (1.46)

6.22 (0.97)

4.50 (1.37)

DAS28-hsCRP, Mean (SD)

5.73 (0.94)

3.93 (1.39)

5.55 (0.91)

3.84 (1.35)

  1. Abbreviations: CDAI Clinical Disease Activity Index, DAS28 Disease Activity Score modified to include the 28 diarthrodial joint count, ESR erythrocyte sedimentation rate, HAQ-DI Health Assessment Questionnaire-Disability Index, hsCRP high-sensitivity C-reactive protein, n number of patients, MJS morning joint stiffness, PhGA Physician’s Global Assessment of Disease Activity, QIDS-SR 16 Quick Inventory of Depressive Symptomatology Self-Rated-16, SD standard deviation, SF-36, 36-Item Short Form Health Survey version 2 with Acute recall
  2. aDaily diary responses were n = 537(Day 1) and n = 1281 (Week 12); nondiary assessments had approximately n = 1301 (Day 1) and n = 1250 (Week 12)
  3. bDaily diary responses were n = 310 (Day 1) and n = 666 (Week 12); nondairy assessments had approximately n = 680 (Day 1) and n = 644 (Week 12)
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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