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Table 4 Pearson Correlations between Severity of Worst Tiredness and Other Instruments in RA-BEAM and RA-BUILD at Week 12

From: Psychometric properties of the single-item measure, severity of worst tiredness, in patients with moderately to severely active rheumatoid arthritis

Instruments

Severity of Worst Tiredness

RA-BEAM

RA-BUILD

n

r

n

r

Week 12a

    

 Duration of MJS

1281

0.32***

666

0.38***

 Severity of MJS

1281

0.79***

666

0.77***

 Severity of Worst Joint Pain

1281

0.82***

666

0.82***

 SF-36

    

  Role Physical Domain

1233

−0.45***

632

−0.42***

  Bodily Pain Domain

1233

−0.51***

632

−0.52***

  General Health Domain

1233

−0.39***

632

−0.38***

  Social Functioning Domain

1233

−0.43***

632

−0.44***

  Vitality Domain

1233

−0.52***

632

−0.51***

  Role Emotional Domain

1233

−0.41***

632

−0.32***

  Mental Health Domain

1233

−0.40***

632

−0.34***

  Physical Functioning Domain

1233

−0.43***

632

−0.41***

  Mental Component Score

1233

−0.40***

632

−0.34***

  Physical Component Score

1233

−0.45***

632

−0.45***

 FACIT-F Total Score

1233

−0.60***

632

−0.60***

 HAQ-DI Total Score

1233

0.49***

632

0.46***

 QIDS-SR16 Total Score

1231

0.37***

632

0.37***

 Patient’s Assessment of Pain

1233

0.69***

632

0.65***

 PtGA

1233

0.64***

632

0.62***

 Tender Joint Count 28

1231

0.32***

630

0.40***

 Swollen Joint Count 28

1231

0.21***

630

0.23***

 PhGA

1224

0.35***

627

0.38***

 hsCRP

1220

0.46***

623

0.49***

  1. Abbreviations: FACIT-F = Functional Assessment of Chronic Illness Therapy-Fatigue; HAQ-DI = Health Assessment Questionnaire-Disability Index; hsCRP = high-sensitivity C-reactive protein; MJS = morning joint stiffness; n = number of patients; PtGA = Patient’s Global Assessment of Disease Activity; PhGA = Physician’s Global Assessment of Disease Activity; QIDS-SR16 = Quick Inventory of Depressive Symptomatology Self-Rated-16; SF-36 = 36-Item Short Form Health Survey version 2 with Acute recall
  2. Pearson correlation coefficients with significance using p-values denoted as: * ≤ 0.05, ** ≤ 0.01, *** ≤ 0.001
  3. aDaily average of seven days preceding visit that contained at least 4 measurements