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Table 2 Summary of reviews identified

From: Measuring quality of life among people living with HIV: a systematic review of reviews

Paper Aim of the review Dates of search Databases and other sources Search terms Language restriction? No. papers reviewed No. HRQoL measures identified No. generic HRQoL measures No. HIV-specific measures
Carabin et al. (2008) [17] To assist clinicians in choosing the most appropriate instrument to measure health related quality of life among people living with HIV. Not stated OVID, Pubmed and ERIC English language Not stated English and Spanish Not stated 17 6 11
Clayson et al. (2006) [4] To review existing HR-QOL measures reported in the HIV/AIDS literature since 1990 and identify those most worthy of consideration for use in clinical trials. 1990-not stated General abstract databases such as MEDLINE, PsycINFO, INSPEC, EMBASE, CINAHL
PRO instrument databases such as the On-Line Guide to Quality of Life Assessment (OLGA) and the Quality of Life Instruments Database (QOLID)
Not stated Not stated Not stated 34 17 17
Cochrane Library Database
International Society for Quality of Life Research and the International Society for Pharmacoeconomics and Outcomes Research abstracts and conference proceedings
Specific HIV-related journals, including AIDS, AIDS
Care, International Journal of STD & AIDS and Journal of Acquired Immune Deficiency Syndrome.
Colautti et al. (2006) [18] To review validated questionnaires to assess health related quality of life in HIV/AIDS patients Not stated PubMed, Medline and Medscape “HRQL”, “questionnaire” and “HIV” None Not stated 20 9 11
Davis & Pathak (2001) [19] To provide a comparative evaluation of psychometric properties of four HIV disease–specific quality-of-life (QoL) instruments. Not stated MEDLINE, Health Star, International Pharmacy Abstracts, Social Sciences Citation Index, Current Contents
Manual reference list search
Not stated Not stated Not stated 4 0 4
Drewes et al. (2013) [3] To provide a comprehensive summary of the methodological approaches used to study the QOL of people with HIV and AIDS based on published research. To early 2011 PubMed and PsycINFO “HIV/AIDS,” “quality of life,” and related concepts, like “well-being,” “life satisfaction,” and the names of established QOL instruments. English abstract 852 >40 (but only report on the 14 most commonly used QOL measures) 8 6
Gakhar et al. (2013) [12] To provide an overview of the Health Related Quality of Life tools available, the methods used for validation, the impact that ART has had on the HRQOL of HIV-infected people, as well as looking at some of the most important adverse effects of ARVs and co-morbidities. Not stated PubMed, Web of Science, Cochrane, MEDLINE and Scopus.
Manual reference list search
Internet databases to look for other HRQOL tools (http://www.proqolid.org).
Included “HIV,” “HRQOL Measures,” “quality of life” and “health status.” English Not stated 41 23 18
Robberstad & Olsen (2010) [13] To review the existing evidence on health related quality of life in HIV/AIDS patients in sub-Saharan Africa and consider how this information is used in the economic evaluation literature. Not stated PubMed, Embase and ISI
Expert input
“HIV OR AIDS”, “Africa south of the Sahara” AND “health related quality of life” Not stated 29 24 6 18 (only describe 3)
Simpson et al. (2013) [11] To identify and classify PRO instruments used to measure treatment effects in clinical trials evaluating NNRTIs. March 2003–Feb 2013 PubMed
Manual reference list search
Included a combination of MeSH terms for HIV [HIV OR HIV infections], MeSH terms associated with PROs/instruments [questionnaires OR interviews as topic OR quality of life OR patient satisfaction OR self-evaluation programs], Substance Names of NNRTIs [efavirenz OR nevirapine OR delavirdine OR etravirine OR rilpivirine OR efavirenz, emtricitabine, tenofovir disoproxil fumarate drug combination], and clinical trial Publication Types [clinical trial OR clinical trial, phase IV OR clinical trial, phase III OR clinical trial, phase II OR controlled clinical trial OR randomized controlled trial] English 26 8 4 4
Skevington & O’Connell (2003) [20] To address issues surrounding the measurement of quality of life of people living with HIV and AIDS and discuss the properties of suitable instruments Jan 1995–May 2000 EMBASE, MEDLINE, the Web of Science (Version 4.1), PubMed. And Psychlit ‘quality of life’ with ‘HIV’ and/or ‘AIDS’
Names of particular QOL scales (e.g. Euroqol, SF-36) AND HIV/AIDS
Not stated Not stated 21 10 11
Wu et al. (2013) [10] To examine the responsiveness of two health-related quality of life (HRQL) instruments used in clinical trials involving HIV-infected adults: the HIV-targeted Medical Outcomes Study HIV Health Survey (MOS-HIV), and a generic measure, the EuroQol-5D (EQ-5D). 2001–2010 PubMed
Manual reference list search
Included a combination of MeSH terms for HIV [HIV OR HIV infections], instrument names [Euroqol, EQ-5D, MOS-HIV], and clinical trial Publication Types [clinical trial OR clinical trial, phase IV OR clinical trial, phase III OR clinical trial, phase II OR controlled clinical trial OR randomized controlled trial] English 17 2 1 1