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Table 2 Key for Tables 1 and 3 Interpreting the direction of effect in included reviews

From: The effectiveness of integrated care interventions in improving patient quality of life (QoL) for patients with chronic conditions. An overview of the systematic review evidence

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Interpretation

↑

At least half of a given review’s included primary studies showed a statistically significant increase in a particular outcome following the intervention (or pooled results from a meta-analysis indicated a statistically significant positive association)

↓

At least half of a given review’s included primary studies showed a statistically significant decrease in a particular outcome following the intervention (or pooled results from a meta-analysis indicated a statistically significant negative association)

↔

A review reported mixed findings i.e. some primary studies may have shown a significant difference between intervention and control groups whereas others showed no significant differences

=

A review where no significant differences between intervention and control groups were reported in any of the included primary studies